PAR1 and PAR2 couple to overlapping and distinct sets of G proteins and linked signaling pathways to differentially regulate cell physiology
about
Blood-brain barrier integrity and glial support: mechanisms that can be targeted for novel therapeutic approaches in strokeSerine proteases, serine protease inhibitors, and protease-activated receptors: roles in synaptic function and behaviorDifferential signaling by protease-activated receptors: implications for therapeutic targeting.Regulation of protease-activated receptor signaling by post-translational modifications.Neutrophil elastase acts as a biased agonist for proteinase-activated receptor-2 (PAR2)Regulator of G protein signaling 2 (RGS2) and RGS4 form distinct G protein-dependent complexes with protease activated-receptor 1 (PAR1) in live cells.Activated protein C: biased for translation.Protease-activated receptor-2 modulates protease-activated receptor-1-driven neointimal hyperplasia.Protease Activated Receptors 1 and 2 Correlate Differently with Breast Cancer Aggressiveness Depending on Tumor ER StatusGenetic targeting of protease activated receptor 2 reduces inflammatory astrogliosis and improves recovery of function after spinal cord injuryInteraction of Protease-Activated Receptor 2 with G Proteins and β-Arrestin 1 Studied by Bioluminescence Resonance Energy Transfer.PAR-2 triggers placenta-derived protease-induced altered VE-cadherin reorganization at endothelial junctions in preeclampsia.Activation of ATP secretion via volume-regulated anion channels by sphingosine-1-phosphate in RAW macrophages.Factor VIIa regulates the expression of caspase-3, MMP-9, and CD44 in SW620 colon cancer cells involving PAR2/MAPKs/NF-κB signaling pathways.Protease-activated-receptor-2 affects protease-activated-receptor-1-driven breast cancer.Palmitoylation of human proteinase-activated receptor-2 differentially regulates receptor-triggered ERK1/2 activation, calcium signalling and endocytosis.Novel role of proline-rich nonreceptor tyrosine kinase 2 in vascular wall remodeling after balloon injuryProtease-activated receptor 1 (PAR1) coupling to G(q/11) but not to G(i/o) or G(12/13) is mediated by discrete amino acids within the receptor second intracellular loop.G protein coupled receptor signaling complexes in live cells.The Role of PAR2 in TGF-β1-Induced ERK Activation and Cell Motility.Astrocytes and the Warning Signs of Intracerebral Hemorrhagic Stroke.SUR1-TRPM4 channel activation and phasic secretion of MMP-9 induced by tPA in brain endothelial cells.
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PAR1 and PAR2 couple to overlapping and distinct sets of G proteins and linked signaling pathways to differentially regulate cell physiology
description
2010 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հունիսին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2010
@ast
im Juni 2010 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2010/06/01)
@sk
vědecký článek publikovaný v roce 2010
@cs
wetenschappelijk artikel (gepubliceerd op 2010/06/01)
@nl
наукова стаття, опублікована в червні 2010
@uk
مقالة علمية (نشرت في يونيو 2010)
@ar
name
PAR1 and PAR2 couple to overla ...... ially regulate cell physiology
@ast
PAR1 and PAR2 couple to overla ...... ially regulate cell physiology
@en
PAR1 and PAR2 couple to overla ...... ially regulate cell physiology
@nl
type
label
PAR1 and PAR2 couple to overla ...... ially regulate cell physiology
@ast
PAR1 and PAR2 couple to overla ...... ially regulate cell physiology
@en
PAR1 and PAR2 couple to overla ...... ially regulate cell physiology
@nl
prefLabel
PAR1 and PAR2 couple to overla ...... ially regulate cell physiology
@ast
PAR1 and PAR2 couple to overla ...... ially regulate cell physiology
@en
PAR1 and PAR2 couple to overla ...... ially regulate cell physiology
@nl
P2093
P2860
P356
P1476
PAR1 and PAR2 couple to overla ...... ially regulate cell physiology
@en
P2093
John R. Hepler
Kelly L. McCoy
Stephen F. Traynelis
P2860
P304
P356
10.1124/MOL.109.062018
P577
2010-06-01T00:00:00Z