Expression, localization, and biochemical characterization of nicotinamide mononucleotide adenylyltransferase 2
about
The Highwire ubiquitin ligase promotes axonal degeneration by tuning levels of Nmnat proteinTwo for the Price of One: A Neuroprotective Chaperone Kit within NAD Synthase Protein NMNAT2The biochemical pathways of central nervous system neural degeneration in niacin deficiency.Nicotinamide mononucleotide adenylyltransferase 2 (Nmnat2) regulates axon integrity in the mouse embryo.Simultaneous single-sample determination of NMNAT isozyme activities in mouse tissues.Identification of palmitoyltransferase and thioesterase enzymes that control the subcellular localization of axon survival factor nicotinamide mononucleotide adenylyltransferase 2 (NMNAT2)Subcellular localization determines the stability and axon protective capacity of axon survival factor Nmnat2.CREB-activity and nmnat2 transcription are down-regulated prior to neurodegeneration, while NMNAT2 over-expression is neuroprotective, in a mouse model of human tauopathyImpact of Genetic Reduction of NMNAT2 on Chemotherapy-Induced Losses in Cell Viability In Vitro and Peripheral Neuropathy In VivoNMNAT2:HSP90 Complex Mediates Proteostasis in Proteinopathies.Screening with an NMNAT2-MSD platform identifies small molecules that modulate NMNAT2 levels in cortical neurons.SIRT3 regulates cell proliferation and apoptosis related to energy metabolism in non-small cell lung cancer cells through deacetylation of NMNAT2NMNATs, evolutionarily conserved neuronal maintenance factors.Axonal trafficking of NMNAT2 and its roles in axon growth and survival in vivo.MAPK signaling promotes axonal degeneration by speeding the turnover of the axonal maintenance factor NMNAT2.Diversification of NAD biological role: the importance of location.Decreased SMG7 expression associates with lupus-risk variants and elevated antinuclear antibody productionUbiquitously expressed genes participate in cell-specific functions via alternative promoter usage.Lack of nicotinamide mononucleotide adenylyltransferase 2 (Nmnat2): consequences for mouse bladder development and function.An expanded toolkit for gene tagging based on MiMIC and scarless CRISPR tagging inDownregulated SIRT6 and upregulated NMNAT2 are associated with the presence, depth and stage of colorectal cancer
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P2860
Expression, localization, and biochemical characterization of nicotinamide mononucleotide adenylyltransferase 2
description
2010 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Journal of Biological Chemistry
@fr
artículu científicu espublizáu en 2010
@ast
im Dezember 2010 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2010/12/17)
@sk
vědecký článek publikovaný v roce 2010
@cs
wetenschappelijk artikel (gepubliceerd op 2010/12/17)
@nl
наукова стаття, опублікована в грудні 2010
@uk
name
Expression, localization, and ...... cleotide adenylyltransferase 2
@ast
Expression, localization, and ...... cleotide adenylyltransferase 2
@en
Expression, localization, and ...... cleotide adenylyltransferase 2
@nl
type
label
Expression, localization, and ...... cleotide adenylyltransferase 2
@ast
Expression, localization, and ...... cleotide adenylyltransferase 2
@en
Expression, localization, and ...... cleotide adenylyltransferase 2
@nl
prefLabel
Expression, localization, and ...... cleotide adenylyltransferase 2
@ast
Expression, localization, and ...... cleotide adenylyltransferase 2
@en
Expression, localization, and ...... cleotide adenylyltransferase 2
@nl
P2093
P2860
P921
P3181
P356
P1476
Expression, localization, and ...... cleotide adenylyltransferase 2
@en
P2093
Colleen M. Dewey
Daniel R. Dries
Hong Zhang
Nian Huang
Paul R. Mayer
P2860
P304
40387–40396
P3181
P356
10.1074/JBC.M110.178913
P407
P577
2010-12-17T00:00:00Z