Acceleration of polycystic kidney disease progression in cpk mice carrying a deletion in the homeodomain protein Cux1

Acceleration of polycystic kidney disease progression in cpk mice carrying a deletion in the homeodomain protein Cux1

Item
http://www.wikidata.org/entity/Q28594958
Kidney: polycystic kidney disease.Cut-like homeobox 1 (CUX1) regulates expression of the fat mass and obesity-associated and retinitis pigmentosa GTPase regulator-interacting protein-1-like (RPGRIP1L) genes and coordinates leptin receptor signaling.Ectopic expression of Cux1 is associated with reduced p27 expression and increased apoptosis during late stage cyst progression upon inactivation of Pkd1 in collecting ducts.Cell cycle arrest in node cells governs ciliogenesis at the node to break left-right symmetry.Ouabain activates the Na-K-ATPase signalosome to induce autosomal dominant polycystic kidney disease cell proliferation.Glycogen synthase kinase-3β promotes cyst expansion in polycystic kidney diseaseA cAMP and CREB-mediated feed-forward mechanism regulates GSK3β in polycystic kidney disease.Specialized roles for cysteine cathepsins in health and disease.Functional Diversity of Ciliary Proteins in Bone Development and Disease.Insights into autosomal dominant polycystic kidney disease by quantitative mass spectrometry-based proteomics.Chronic cathepsin inhibition by E-64 in Dahl salt-sensitive rats.Cathepsin K activity controls injury-related vascular repair in mice.CUX1 transcription factor is required for optimal ATM/ATR-mediated responses to DNA damage.The roles of CUX1 homeodomain proteins in the establishment of a transcriptional program required for cell migration and invasion.Cux1 promotes cell proliferation and polycystic kidney disease progression in an ADPKD mouse model.Urine peptidome analysis predicts risk of end-stage renal disease and reveals proteolytic pathways involved in autosomal dominant polycystic kidney disease progression.
P2860

Acceleration of polycystic kidney disease progression in cpk mice carrying a deletion in the homeodomain protein Cux1

Item
http://www.wikidata.org/entity/Q28594958
description
2008 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2008
@ast
im Dezember 2008 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2008/12/01)
@sk
vědecký článek publikovaný v roce 2008
@cs
wetenschappelijk artikel (gepubliceerd op 2008/12/01)
@nl
наукова стаття, опублікована в грудні 2008
@uk
مقالة علمية (نشرت في ديسمبر 2008)
@ar
name
Acceleration of polycystic kid ...... n the homeodomain protein Cux1
@ast
Acceleration of polycystic kid ...... n the homeodomain protein Cux1
@en
Acceleration of polycystic kid ...... n the homeodomain protein Cux1
@nl
type
label
Acceleration of polycystic kid ...... n the homeodomain protein Cux1
@ast
Acceleration of polycystic kid ...... n the homeodomain protein Cux1
@en
Acceleration of polycystic kid ...... n the homeodomain protein Cux1
@nl
prefLabel
Acceleration of polycystic kid ...... n the homeodomain protein Cux1
@ast
Acceleration of polycystic kid ...... n the homeodomain protein Cux1
@en
Acceleration of polycystic kid ...... n the homeodomain protein Cux1
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P433
P478
P50
P577
P5875
P698
P921
P932
P356
P1433
P1476
Acceleration of polycystic kid ...... n the homeodomain protein Cux1
@en
P2093
P2860
P304
P31
P356
10.1152/AJPRENAL.90420.2008
P433
P478
P50
P577
P5875
P698
P921
P932