Loss of the Birt-Hogg-Dubé tumor suppressor results in apoptotic resistance due to aberrant TGFβ-mediated transcription
about
Genetic characterization of the Drosophila birt-hogg-dubé syndrome geneFolliculin interacts with p0071 (plakophilin-4) and deficiency is associated with disordered RhoA signalling, epithelial polarization and cytokinesisFLCN, a novel autophagy component, interacts with GABARAP and is regulated by ULK1 phosphorylationBirt-Hogg-Dube syndrome: clinicopathological features of the lungRegulation of Bim in Health and DiseaseFolliculin regulates ampk-dependent autophagy and metabolic stress survivalRegulation of mitochondrial oxidative metabolism by tumor suppressor FLCNThe folliculin-FNIP1 pathway deleted in human Birt-Hogg-Dubé syndrome is required for murine B-cell developmentFolliculin controls lung alveolar enlargement and epithelial cell survival through E-cadherin, LKB1, and AMPK.Birt-Hogg-Dubé: tumour suppressor function and signalling dynamics central to folliculin.Folliculin regulates cell-cell adhesion, AMPK, and mTORC1 in a cell-type-specific manner in lung-derived cells.Distinctive expression patterns of glycoprotein non-metastatic B and folliculin in renal tumors in patients with Birt-Hogg-Dubé syndrome.Folliculin-interacting proteins Fnip1 and Fnip2 play critical roles in kidney tumor suppression in cooperation with Flcn.FLCN Maintains the Leucine Level in Lysosome to Stimulate mTORC1.Clinical Features, Genetics and Potential Therapeutic Approaches for Birt-Hogg-Dubé Syndrome.Lst4, the yeast Fnip1/2 orthologue, is a DENN-family protein.Birt-Hogg-Dubé syndrome: from gene discovery to molecularly targeted therapies.Loss of Folliculin Disrupts Hematopoietic Stem Cell Quiescence and Homeostasis Resulting in Bone Marrow Failure.Genetic modification of dividing cells using episomally maintained S/MAR DNA vectors.Recruitment of folliculin to lysosomes supports the amino acid-dependent activation of Rag GTPasesThe folliculin tumor suppressor is a GAP for the RagC/D GTPases that signal amino acid levels to mTORC1.Molecular genetics and clinical features of Birt-Hogg-Dubé syndrome.Birt-Hogg-Dubé syndrome: a case report and a review of the literature.Over-production of nitric oxide by oxidative stress-induced activation of the TGF-β1/PI3K/Akt pathway in mesangial cells cultured in high glucoseFolliculin directs the formation of a Rab34-RILP complex to control the nutrient-dependent dynamic distribution of lysosomes.Oncocytoma-like renal tumor with transformation toward high-grade oncocytic carcinoma: a unique case with morphologic, immunohistochemical, and genomic characterization.Birt-Hogg-Dube syndrome is a novel ciliopathy.Loss of the Birt-Hogg-Dubé gene product folliculin induces longevity in a hypoxia-inducible factor-dependent manner.Recurrent renal cancer in Birt-Hogg-Dubé syndrome: A case report.FLCN: The causative gene for Birt-Hogg-Dubé syndrome.Genomic profiling reveals distinctive molecular relapse patterns in IDH1/2 wild-type glioblastoma.
P2860
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P2860
Loss of the Birt-Hogg-Dubé tumor suppressor results in apoptotic resistance due to aberrant TGFβ-mediated transcription
description
2011 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հունիսին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2011
@ast
im Juni 2011 veröffentlichter wissenschaftlicher Artikel
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scientific journal article
@en
vedecký článok (publikovaný 2011/06/02)
@sk
vědecký článek publikovaný v roce 2011
@cs
wetenschappelijk artikel (gepubliceerd op 2011/06/02)
@nl
наукова стаття, опублікована в червні 2011
@uk
مقالة علمية (نشرت في 2-6-2011)
@ar
name
Loss of the Birt-Hogg-Dubé tum ...... nt TGFβ-mediated transcription
@ast
Loss of the Birt-Hogg-Dubé tum ...... nt TGFβ-mediated transcription
@en
Loss of the Birt-Hogg-Dubé tum ...... nt TGFβ-mediated transcription
@nl
type
label
Loss of the Birt-Hogg-Dubé tum ...... nt TGFβ-mediated transcription
@ast
Loss of the Birt-Hogg-Dubé tum ...... nt TGFβ-mediated transcription
@en
Loss of the Birt-Hogg-Dubé tum ...... nt TGFβ-mediated transcription
@nl
prefLabel
Loss of the Birt-Hogg-Dubé tum ...... nt TGFβ-mediated transcription
@ast
Loss of the Birt-Hogg-Dubé tum ...... nt TGFβ-mediated transcription
@en
Loss of the Birt-Hogg-Dubé tum ...... nt TGFβ-mediated transcription
@nl
P2093
P2860
P3181
P356
P1433
P1476
Loss of the Birt-Hogg-Dubé tum ...... nt TGFβ-mediated transcription
@en
P2093
E. P. Henske
J. J. Gruber
M. C. Simon
T. P. Cash
T. R. Hartman
P2860
P2888
P304
P3181
P356
10.1038/ONC.2010.628
P407
P577
2011-06-02T00:00:00Z
P5875
P6179
1005269709