A novel locus of resistance to severe malaria in a region of ancient balancing selection
about
Expanding the antimalarial toolkit: Targeting host-parasite interactionsRecent advances in malaria genomics and epigenomicsAdmixture into and within sub-Saharan AfricaAsymptomatic Plasmodium infections in 18 villages of southern Savannakhet Province, Lao PDR (Laos)Glycophorins, Blood Groups, and Protection from Severe MalariaPlasmodium falciparum erythrocyte-binding antigen 175 triggers a biophysical change in the red blood cell that facilitates invasionGenetic mutations you want.Malaria hotspots defined by clinical malaria, asymptomatic carriage, PCR and vector numbers in a low transmission area on the Kenyan CoastEnvironmental Correlation Analysis for Genes Associated with Protection against MalariaThe Legacy of Past Pandemics: Common Human Mutations That Protect against Infectious Disease.Characterisation of the opposing effects of G6PD deficiency on cerebral malaria and severe malarial anaemia.NK Cells: Uncertain Allies against Malaria.Structure-Guided Identification of a Family of Dual Receptor-Binding PfEMP1 that Is Associated with Cerebral Malaria.Resistance to malaria through structural variation of red blood cell invasion receptors.EBT: A Statistic Test Identifying Moderate Size of Significant Features with Balanced Power and Precision for Genome-wide Rate Comparisons.The role of the red blood cell in host defence against falciparum malaria: an expanding repertoire of evolutionary alterations.Variant surface antigens of Plasmodium falciparum and their roles in severe malaria.The genomic landscape of African populations in health and disease.Major transcriptional changes observed in the Fulani, an ethnic group less susceptible to malaria.Diversity and inclusion in genomic research: why the uneven progress?High rate of adaptation of mammalian proteins that interact with Plasmodium and related parasites.Long-term balancing selection contributes to adaptation in Arabidopsis and its relatives.Detecting signatures of past pathogen selection on human HLA loci: are there needles in the haystack?Plasmodium reichenowi EBA-140 merozoite ligand binds to glycophorin D on chimpanzee red blood cells, shedding new light on origins of Plasmodium falciparum.Glycophorin alleles link to malaria protection.Evaluating the Causal Link Between Malaria Infection and Endemic Burkitt Lymphoma in Northern Uganda: A Mendelian Randomization Study.Beyond Hemoglobin: Screening for Malaria Host Factors.Novel genetic polymorphisms associated with severe malaria and under selective pressure in North-eastern Tanzania.Two complement receptor one alleles have opposing associations with cerebral malaria and interact with α+thalassaemia.Genomes of all known members of a Plasmodium subgenus reveal paths to virulent human malaria.Risk of nontyphoidal Salmonella bacteraemia in African children is modified by STAT4.Signatures of Long-Term Balancing Selection in Human Genomes.Beta-globin gene haplotypes and selected Malaria-associated variants among black Southern African populations.An in vitro erythrocyte preference assay reveals that Plasmodium falciparum parasites prefer Type O over Type A erythrocytes.Human Genomic Loci Important in Common Infectious Diseases: Role of High-Throughput Sequencing and Genome-Wide Association Studies.Human candidate gene polymorphisms and risk of severe malaria in children in Kilifi, Kenya: a case-control association studyThe Malaria-Protective Human Glycophorin Structural Variant DUP4 Shows Somatic Mosaicism and Association with Hemoglobin Levels
P2860
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P2860
A novel locus of resistance to severe malaria in a region of ancient balancing selection
description
2015 nî lūn-bûn
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2015 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2015 թվականի հոտեմբերին հրատարակված գիտական հոդված
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2015年の論文
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2015年学术文章
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2015年学术文章
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2015年学术文章
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2015年学术文章
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2015年学术文章
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2015年學術文章
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name
A novel locus of resistance to severe malaria in a region of ancient balancing selection
@ast
A novel locus of resistance to severe malaria in a region of ancient balancing selection
@en
A novel locus of resistance to severe malaria in a region of ancient balancing selection
@nl
type
label
A novel locus of resistance to severe malaria in a region of ancient balancing selection
@ast
A novel locus of resistance to severe malaria in a region of ancient balancing selection
@en
A novel locus of resistance to severe malaria in a region of ancient balancing selection
@nl
prefLabel
A novel locus of resistance to severe malaria in a region of ancient balancing selection
@ast
A novel locus of resistance to severe malaria in a region of ancient balancing selection
@en
A novel locus of resistance to severe malaria in a region of ancient balancing selection
@nl
P2860
P50
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P356
P1433
P1476
A novel locus of resistance to severe malaria in a region of ancient balancing selection
@en
P2093
Chris C A Spencer
Kirk A Rockett
P2860
P2888
P3181
P356
10.1038/NATURE15390
P407
P577
2015-10-08T00:00:00Z
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P6179
1048572776