Pak1 kinase homodimers are autoinhibited in trans and dissociated upon activation by Cdc42 and Rac1
about
POSH2 is a RING finger E3 ligase with Rac1 binding activity through a partial CRIB domainThe emerging importance of group II PAKsSpatiotemporal regulation of the kinase Mst1 by binding protein RAPL is critical for lymphocyte polarity and adhesionCCM3/PDCD10 heterodimerizes with germinal center kinase III (GCKIII) proteins using a mechanism analogous to CCM3 homodimerizationPak1 and PIX regulate contact inhibition during epithelial wound healingGroup I and II mammalian PAKs have different modes of activation by Cdc42PAK5 kinase is an inhibitor of MARK/Par-1, which leads to stable microtubules and dynamic actin.Nucleocytoplasmic shuttling of Pak5 regulates its antiapoptotic propertiesGGAPs, a new family of bifunctional GTP-binding and GTPase-activating proteinsA walk-through of the yeast mating pheromone response pathwayRegulation of small GTPases by GEFs, GAPs, and GDIsA new genetically encoded single-chain biosensor for Cdc42 based on FRET, useful for live-cell imagingMitotic exit regulation through distinct domains within the protein kinase Cdc15.Cdc42 regulation of kinase activity and signaling by the yeast p21-activated kinase Ste20.Signaling, Regulation, and Specificity of the Type II p21-activated KinasesRegulation of WNK1 by an autoinhibitory domain and autophosphorylationJAK2 tyrosine kinase phosphorylates PAK1 and regulates PAK1 activity and functionsPAK1-mediated MORC2 phosphorylation promotes gastric tumorigenesisThe Role of the Pleckstrin Homology Domain-containing Protein CKIP-1 in Activation of p21-activated Kinase 1 (PAK1)PAK6 targets to cell-cell adhesions through its N-terminus in a Cdc42-dependent manner to drive epithelial colony escapeAn isoform-selective, small-molecule inhibitor targets the autoregulatory mechanism of p21-activated kinaseActivation of p21-activated kinase 6 by MAP kinase kinase 6 and p38 MAP kinaseProtein kinase CK2 phosphorylates and activates p21-activated kinase 1Antioxidant Treatment and Induction of Autophagy Cooperate to Reduce Desmin Aggregation in a Cellular Model of DesminopathyDissecting activation of the PAK1 kinase at protrusions in living cells.Cdc42/Rac1-mediated activation primes PAK2 for superactivation by tyrosine phosphorylation.3D structure analysis of PAKs: A clue to the rational design for affinity reagents and blockers.LAT-independent Erk activation via Bam32-PLC-γ1-Pak1 complexes: GTPase-independent Pak1 activation.Cdc42 induces activation loop phosphorylation and membrane targeting of mixed lineage kinase 3.Identification of phosphorylation sites in betaPIX and PAK1PAK1-Nck regulates cyclin D1 promoter activity in response to prolactinBlocking p21-activated kinase reduces lipopolysaccharide-induced acute lung injury by preventing polymorphonuclear leukocyte infiltration.Improvements to the Kunkel mutagenesis protocol for constructing primary and secondary phage-display libraries.Regulation of insulin signaling by the phosphatidylinositol 3,4,5-triphosphate phosphatase SKIP through the scaffolding function of Pak1Tumor necrosis factor-alpha induced expression of matrix metalloproteinase-9 through p21-activated kinase-1.Interaction with LC8 is required for Pak1 nuclear import and is indispensable for zebrafish developmentReciprocally coupled residues crucial for protein kinase Pak2 activity calculated by statistical coupling analysisThe Rho/Rac exchange factor Vav2 controls nitric oxide-dependent responses in mouse vascular smooth muscle cells.Protein phosphatase 4 is a positive regulator of hematopoietic progenitor kinase 1.Constitutive p21-activated kinase (PAK) activation in breast cancer cells as a result of mislocalization of PAK to focal adhesions
P2860
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P2860
Pak1 kinase homodimers are autoinhibited in trans and dissociated upon activation by Cdc42 and Rac1
description
2002 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի հունվարին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2002
@ast
im Januar 2002 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2002/01/01)
@sk
vědecký článek publikovaný v roce 2002
@cs
wetenschappelijk artikel (gepubliceerd op 2002/01/01)
@nl
наукова стаття, опублікована в січні 2002
@uk
مقالة علمية (نشرت عام 2002)
@ar
name
Pak1 kinase homodimers are aut ...... n activation by Cdc42 and Rac1
@ast
Pak1 kinase homodimers are aut ...... n activation by Cdc42 and Rac1
@en
Pak1 kinase homodimers are aut ...... n activation by Cdc42 and Rac1
@nl
type
label
Pak1 kinase homodimers are aut ...... n activation by Cdc42 and Rac1
@ast
Pak1 kinase homodimers are aut ...... n activation by Cdc42 and Rac1
@en
Pak1 kinase homodimers are aut ...... n activation by Cdc42 and Rac1
@nl
prefLabel
Pak1 kinase homodimers are aut ...... n activation by Cdc42 and Rac1
@ast
Pak1 kinase homodimers are aut ...... n activation by Cdc42 and Rac1
@en
Pak1 kinase homodimers are aut ...... n activation by Cdc42 and Rac1
@nl
P2093
P1433
P1476
Pak1 kinase homodimers are aut ...... n activation by Cdc42 and Rac1
@en
P2093
Bruce J. Mayer
Maria Carla Parrini
Stephen C. Harrison
P356
10.1016/S1097-2765(01)00428-2
P577
2002-01-01T00:00:00Z