Structural determinants in AUF1 required for high affinity binding to A + U-rich elements
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Purification and characterization of beta-adrenergic receptor mRNA-binding proteinsIdentification and cDNA cloning of a novel RNA-binding protein that interacts with the cyclic nucleotide-responsive sequence in the Type-1 plasminogen activator inhibitor mRNAIdentification of domains in apobec-1 complementation factor required for RNA binding and apolipoprotein-B mRNA editing14-3-3sigma is a p37 AUF1-binding protein that facilitates AUF1 transport and AU-rich mRNA decayAssembly of AUF1 with eIF4G-poly(A) binding protein complex suggests a translation function in AU-rich mRNA decayHeterogeneous nuclear ribonucleoprotein D0B is a sequence-specific DNA-binding proteinHighly selective actions of HuR in antagonizing AU-rich element-mediated mRNA destabilizationChaperone Hsp27, a novel subunit of AUF1 protein complexes, functions in AU-rich element-mediated mRNA decayPost-transcriptional control of gene expression by AUF1: mechanisms, physiological targets, and regulationAssembly of AUF1 oligomers on U-rich RNA targets by sequential dimer associationSelective degradation of AU-rich mRNAs promoted by the p37 AUF1 protein isoformTransient CPEB dimerization and translational controlIntracellular localization and interaction of mRNA binding proteins as detected by FRET.The rate of folate receptor alpha (FR alpha) synthesis in folate depleted CHL cells is regulated by a translational mechanism sensitive to media folate levels, while stable overexpression of its mRNA is mediated by gene amplification and an increaseFolding of A+U-rich RNA elements modulates AUF1 binding. Potential roles in regulation of mRNA turnover.Regulation of AUF1 expression via conserved alternatively spliced elements in the 3' untranslated regionVersatile role for hnRNP D isoforms in the differential regulation of cytoplasmic mRNA turnover.Down-regulation of cyclin D1 expression by prostaglandin A(2) is mediated by enhanced cyclin D1 mRNA turnover.Identification of a novel AU-Rich element in the 3' untranslated region of epidermal growth factor receptor mRNA that is the target for regulated RNA-binding proteinsFunctional dissection of hnRNP D suggests that nuclear import is required before hnRNP D can modulate mRNA turnover in the cytoplasmAlternatively expressed domains of AU-rich element RNA-binding protein 1 (AUF1) regulate RNA-binding affinity, RNA-induced protein oligomerization, and the local conformation of bound RNA ligands.RNA-binding protein HuR enhances p53 translation in response to ultraviolet light irradiationUnraveling a cytoplasmic role for hnRNP D in the in vivo mRNA destabilization directed by the AU-rich element.Association of the von Hippel-Lindau protein with AUF1 and posttranscriptional regulation of VEGFA mRNA.AUF1/hnRNP D represses expression of VEGF in macrophages.Nuclear heterogeneous nuclear ribonucleoprotein D is associated with poor prognosis and interactome analysis reveals its novel binding partners in oral cancer.Picornavirus modification of a host mRNA decay protein.Modulation of neoplastic gene regulatory pathways by the RNA-binding factor AUF1The role of AUF1 in regulated mRNA decayPeptides modeled on the RGG domain of AUF1/hnRNP-D regulate 3' UTR-dependent gene expressionCellular mRNA decay protein AUF1 negatively regulates enterovirus and human rhinovirus infections.AUF1 regulation of coding and noncoding RNA.Translation control of TAK1 mRNA by hnRNP K modulates LPS-induced macrophage activation.microRNA-binding proteins: specificity and function.FRET-detectable interactions between the ARE binding proteins, HuR and p37AUF1.Hsp27 and F-box protein β-TrCP promote degradation of mRNA decay factor AUF1.Heterogeneous nuclear ribonucleoprotein D0 contains transactivator and DNA-binding domains.Nuclear import and export functions in the different isoforms of the AUF1/heterogeneous nuclear ribonucleoprotein protein family.Thermodynamics and kinetics of Hsp70 association with A + U-rich mRNA-destabilizing sequences.AUF1(hnRNP D0) dimers bind AU-rich element in 3' UTR of mRNA
P2860
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P2860
Structural determinants in AUF1 required for high affinity binding to A + U-rich elements
description
1997 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Journal of Biological Chemistry
@fr
artículu científicu espublizáu en 1997
@ast
im Oktober 1997 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 1997/10/31)
@sk
vědecký článek publikovaný v roce 1997
@cs
wetenschappelijk artikel (gepubliceerd op 1997/10/31)
@nl
наукова стаття, опублікована в жовтні 1997
@uk
name
Structural determinants in AUF1 required for high affinity binding to A + U-rich elements
@ast
Structural determinants in AUF1 required for high affinity binding to A + U-rich elements
@en
Structural determinants in AUF1 required for high affinity binding to A + U-rich elements
@nl
type
label
Structural determinants in AUF1 required for high affinity binding to A + U-rich elements
@ast
Structural determinants in AUF1 required for high affinity binding to A + U-rich elements
@en
Structural determinants in AUF1 required for high affinity binding to A + U-rich elements
@nl
prefLabel
Structural determinants in AUF1 required for high affinity binding to A + U-rich elements
@ast
Structural determinants in AUF1 required for high affinity binding to A + U-rich elements
@en
Structural determinants in AUF1 required for high affinity binding to A + U-rich elements
@nl
P2093
P2860
P356
P1476
Structural determinants in AUF1 required for high affinity binding to A + U-rich elements
@en
P2093
P2860
P304
27635–27643
P356
10.1074/JBC.272.44.27635
P407
P577
1997-10-31T00:00:00Z