Identification of amino acid residues responsible for the pyrimidine and purine nucleoside specificities of human concentrative Na(+) nucleoside cotransporters hCNT1 and hCNT2
about
Crystal structure of a concentrative nucleoside transporter from Vibrio cholerae at 2.4 ÅStructural basis of nucleoside and nucleoside drug selectivity by concentrative nucleoside transportersSpecificity of human and rat orthologs of the concentrative nucleoside transporter, SPNT.Efficiency of purine utilization by Helicobacter pylori: roles for adenosine deaminase and a NupC homolog.Conserved residues F316 and G476 in the concentrative nucleoside transporter 1 (hCNT1) affect guanosine sensitivity and membrane expression, respectively.Molecular determinants of specificity for synthetic nucleoside analogs in the concentrative nucleoside transporter, CNT2.Cation coupling properties of human concentrative nucleoside transporters hCNT1, hCNT2 and hCNT3.Molecular biology and regulation of nucleoside and nucleobase transporter proteins in eukaryotes and prokaryotes.Nucleoside anticancer drugs: the role of nucleoside transporters in resistance to cancer chemotherapy.A conformationally mobile cysteine residue (Cys-561) modulates Na+ and H+ activation of human CNT3Challenges for the development of ribonucleoside analogues as inducers of error catastrophe.Enhancing Drug Efficacy and Therapeutic Index through Cheminformatics-Based Selection of Small Molecule Binary Weapons That Improve Transporter-Mediated Targeting: A Cytotoxicity System Based on Gemcitabine.Conserved glutamate residues Glu-343 and Glu-519 provide mechanistic insights into cation/nucleoside cotransport by human concentrative nucleoside transporter hCNT3Transporters that translocate nucleosides and structural similar drugs: structural requirements for substrate recognition.A proton-mediated conformational shift identifies a mobile pore-lining cysteine residue (Cys-561) in human concentrative nucleoside transporter 3.Substituted cysteine accessibility method (SCAM) analysis of the transport domain of human concentrative nucleoside transporter 3 (hCNT3) and other family members reveals features of structural and functional importanceA two-step transport pathway allows the mother cell to nurture the developing spore in Bacillus subtilis.Cysteine-accessibility analysis of transmembrane domains 11-13 of human concentrative nucleoside transporter 3.An ancient prevertebrate Na+-nucleoside cotransporter (hfCNT) from the Pacific hagfish (Eptatretus stouti).Electrophysiological characterization of the human Na(+)/nucleoside cotransporter 1 (hCNT1) and role of adenosine on hCNT1 function.Electrophysiological characterization of a recombinant human Na+-coupled nucleoside transporter (hCNT1) produced in Xenopus oocytes.Transport of nucleosides and free purine and pyrimidine bases across the plasma membraneConserved glutamate residues are critically involved in Na+/nucleoside cotransport by human concentrative nucleoside transporter 1 (hCNT1).Concentrative transport (import) of nucleosides plus sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter); member 2Recent molecular advances in studies of the concentrative Na+-dependent nucleoside transporter (CNT) family: identification and characterization of novel human and mouse proteins (hCNT3 and mCNT3) broadly selective for purine and pyrimidine nucleosid
P2860
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P2860
Identification of amino acid residues responsible for the pyrimidine and purine nucleoside specificities of human concentrative Na(+) nucleoside cotransporters hCNT1 and hCNT2
description
1999 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Journal of Biological Chemistry
@fr
artículu científicu espublizáu en 1999
@ast
im August 1999 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 1999/08/27)
@sk
vědecký článek publikovaný v roce 1999
@cs
wetenschappelijk artikel (gepubliceerd op 1999/08/27)
@nl
наукова стаття, опублікована в серпні 1999
@uk
name
Identification of amino acid r ...... cotransporters hCNT1 and hCNT2
@ast
Identification of amino acid r ...... cotransporters hCNT1 and hCNT2
@en
Identification of amino acid r ...... cotransporters hCNT1 and hCNT2
@nl
type
label
Identification of amino acid r ...... cotransporters hCNT1 and hCNT2
@ast
Identification of amino acid r ...... cotransporters hCNT1 and hCNT2
@en
Identification of amino acid r ...... cotransporters hCNT1 and hCNT2
@nl
prefLabel
Identification of amino acid r ...... cotransporters hCNT1 and hCNT2
@ast
Identification of amino acid r ...... cotransporters hCNT1 and hCNT2
@en
Identification of amino acid r ...... cotransporters hCNT1 and hCNT2
@nl
P2093
P2860
P356
P1476
Identification of amino acid r ...... cotransporters hCNT1 and hCNT2
@en
P2093
C. E. Cass
J. D. Young
S. A. Baldwin
S. K. Loewen
P2860
P304
24475–24484
P356
10.1074/JBC.274.35.24475
P407
P577
1999-08-27T00:00:00Z