about
Recruitment and activation of PLCgamma1 in T cells: a new insight into old domainsCrucial structural role for the PH and C1 domains of the Vav1 exchange factorEndogenous RhoG is dispensable for integrin-mediated cell spreading but contributes to Rac-independent migration.T-cell receptor- and CD28-induced Vav1 activity is required for the accumulation of primed T cells into antigenic tissue.Dlgh1 coordinates actin polymerization, synaptic T cell receptor and lipid raft aggregation, and effector function in T cellsRegulatory roles for Tiam1, a guanine nucleotide exchange factor for Rac1, in glucose-stimulated insulin secretion in pancreatic beta-cellsSignaling networks that regulate cell migrationThe use of knockout mice reveals a synergistic role of the Vav1 and Rasgrf2 gene deficiencies in lymphomagenesis and metastasisVAV2 and VAV3 as candidate disease genes for spontaneous glaucoma in mice and humansThe Rho/Rac exchange factor Vav2 controls nitric oxide-dependent responses in mouse vascular smooth muscle cells.Heterozygous deficiency of delta-catenin impairs pathological angiogenesis.Vav1 and Rac control chemokine-promoted T lymphocyte adhesion mediated by the integrin alpha4beta1VAV1 and BAFF, via NFκB pathway, are genetic risk factors for myasthenia gravis.Vav protein guanine nucleotide exchange factor regulates CD36 protein-mediated macrophage foam cell formation via calcium and dynamin-dependent processes.Loss of Vav2 proto-oncogene causes tachycardia and cardiovascular disease in mice.Impaired IL-4 and c-Maf expression and enhanced Th1-cell development in Vav1-deficient mice.Vav3 proto-oncogene deficiency leads to sympathetic hyperactivity and cardiovascular dysfunction.The protooncogene Vav1 regulates murine leukemia virus-induced T-cell leukemogenesis.Function of the nucleotide exchange activity of vav1 in T cell development and activation.The N-terminal 20-amino acid region of guanine nucleotide exchange factor Vav1 plays a distinguished role in T cell receptor-mediated calcium signaling.The emerging role of protein kinase Cθ in cytoskeletal signaling.Genomic expression profiling of TNF-alpha-treated BDC2.5 diabetogenic CD4+ T cells.Lymphocyte signaling: beyond knockouts.Rho family GTPases and their regulators in lymphocytes.Targeted cleavage of signaling proteins by caspase 3 inhibits T cell receptor signaling in anergic T cellsRac GTPases play critical roles in early T-cell developmentCoordinate control of cytoskeletal remodeling and calcium mobilization during T-cell activationAge-related changes in lck-Vav signaling pathways in mouse CD4 T cells.Age-related defects in the cytoskeleton signaling pathways of CD4 T cells.Modulation of CTLA-4 and GITR for cancer immunotherapy.Signaling microdomains in T cells.Balanced Vav2 GEF activity regulates neurite outgrowth and branching in vitro and in vivoCpG-induced tyrosine phosphorylation occurs via a TLR9-independent mechanism and is required for cytokine secretion.RTKN2 Induces NF-KappaB Dependent Resistance to Intrinsic Apoptosis in HEK Cells and Regulates BCL-2 Genes in Human CD4(+) Lymphocytes.Activation of Vav/Rho GTPase signaling by CXCL12 controls membrane-type matrix metalloproteinase-dependent melanoma cell invasion.Involvement of the Rac1-IRSp53-Wave2-Arp2/3 Signaling Pathway in HIV-1 Gag Particle Release in CD4 T Cells.Azathioprine suppresses ezrin-radixin-moesin-dependent T cell-APC conjugation through inhibition of Vav guanosine exchange activity on Rac proteins.CD28 dependent Vav1 pathwayActivation of Vav1Activation of RAC1 by VAV_R-HSA-2871796
P2860
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P2860
description
2003 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2003
@ast
scientific journal article
@en
vedecký článok (publikovaný 2003/04/01)
@sk
vědecký článek publikovaný v roce 2003
@cs
wetenschappelijk artikel (gepubliceerd op 2003/04/01)
@nl
наукова стаття, опублікована у квітні 2003
@uk
مقالة علمية (نشرت في أبريل 2003)
@ar
name
Vav1: a key signal transducer downstream of the TCR
@ast
Vav1: a key signal transducer downstream of the TCR
@en
Vav1: a key signal transducer downstream of the TCR
@nl
type
label
Vav1: a key signal transducer downstream of the TCR
@ast
Vav1: a key signal transducer downstream of the TCR
@en
Vav1: a key signal transducer downstream of the TCR
@nl
prefLabel
Vav1: a key signal transducer downstream of the TCR
@ast
Vav1: a key signal transducer downstream of the TCR
@en
Vav1: a key signal transducer downstream of the TCR
@nl
P2093
P1476
Vav1: a key signal transducer downstream of the TCR
@en
P2093
Antonella Prisco
Laurence Ardouin
Lucinda F. Reynolds
Victor L. J. Tybulewicz
P577
2003-04-01T00:00:00Z