Mutant Cu, Zn superoxide dismutase that causes motoneuron degeneration is present in mitochondria in the CNS
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VAPB interacts with the mitochondrial protein PTPIP51 to regulate calcium homeostasisOlesoxime, a cholesterol-like neuroprotectant for the potential treatment of amyotrophic lateral sclerosisMisfolded CuZnSOD and amyotrophic lateral sclerosisALS-associated mutant SOD1G93A causes mitochondrial vacuolation by expansion of the intermembrane space and by involvement of SOD1 aggregation and peroxisomesPrimary glia expressing the G93A-SOD1 mutation present a neuroinflammatory phenotype and provide a cellular system for studies of glial inflammationUltrastructural studies of ALS mitochondria connect altered function and permeability with defects of mitophagy and mitochondriogenesisSOD1 misplacing and mitochondrial dysfunction in amyotrophic lateral sclerosis pathogenesisOxidative stress and cerebral endothelial cells: regulation of the blood-brain-barrier and antioxidant based interventionsMechanisms of mutant SOD1 induced mitochondrial toxicity in amyotrophic lateral sclerosisThe complex molecular biology of amyotrophic lateral sclerosis (ALS)Exploring new pathways of neurodegeneration in ALS: the role of mitochondria quality controlIncreased expression of a proline-rich Akt substrate (PRAS40) in human copper/zinc-superoxide dismutase transgenic rats protects motor neurons from death after spinal cord injuryS-nitrosothiol depletion in amyotrophic lateral sclerosis.Mitochondrial proteomic analysis of a cell line model of familial amyotrophic lateral sclerosis.An in vitro model for Lewy body-like hyaline inclusion/astrocytic hyaline inclusion: induction by ER stress with an ALS-linked SOD1 mutationStem cell-derived motor neurons: applications and challenges in amyotrophic lateral sclerosis.ALS-linked mutant SOD1 damages mitochondria by promoting conformational changes in Bcl-2.Mitochondrial pathobiology in ALS.Mitochondrial dysfunction and intracellular calcium dysregulation in ALSGlutaredoxin 2 prevents aggregation of mutant SOD1 in mitochondria and abolishes its toxicity.Inducible nitric oxide synthase is present in motor neuron mitochondria and Schwann cells and contributes to disease mechanisms in ALS miceMitochondrial and Cell Death Mechanisms in Neurodegenerative Diseases.Programmed cell death in amyotrophic lateral sclerosisFamilial ALS-superoxide dismutases associate with mitochondria and shift their redox potentials.Motor neuron trophic factors: therapeutic use in ALS?Defective mitochondrial dynamics is an early event in skeletal muscle of an amyotrophic lateral sclerosis mouse model.Biochemical properties and in vivo effects of the SOD1 zinc-binding site mutant (H80G)Molecular and cellular pathways of neurodegeneration in motor neurone diseaseThe role of environmental exposures in neurodegeneration and neurodegenerative diseases.Mitochondria as a therapeutic target for aging and neurodegenerative diseases.Familial amyotrophic lateral sclerosis-linked SOD1 mutants perturb fast axonal transport to reduce axonal mitochondria content.Misfolded proteins, endoplasmic reticulum stress and neurodegeneration.An Adaptation to Low Copper in Candida albicans Involving SOD Enzymes and the Alternative Oxidase.Compartment-dependent mitochondrial alterations in experimental ALS, the effects of mitophagy and mitochondriogenesisBiology of mitochondria in neurodegenerative diseases.Selective association of misfolded ALS-linked mutant SOD1 with the cytoplasmic face of mitochondria.Activation of superoxide dismutases: putting the metal to the pedal.Isolated cytochrome c oxidase deficiency in G93A SOD1 mice overexpressing CCS proteinTranscriptome Profiling Following Neuronal and Glial Expression of ALS-Linked SOD1 in Drosophila.Mitochondria in neurodegeneration.
P2860
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P2860
Mutant Cu, Zn superoxide dismutase that causes motoneuron degeneration is present in mitochondria in the CNS
description
2002 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի մարտին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2002
@ast
im März 2002 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2002/03/15)
@sk
vědecký článek publikovaný v roce 2002
@cs
wetenschappelijk artikel (gepubliceerd op 2002/03/15)
@nl
наукова стаття, опублікована в березні 2002
@uk
مقالة علمية (نشرت في 15-3-2002)
@ar
name
Mutant Cu, Zn superoxide dismu ...... ent in mitochondria in the CNS
@ast
Mutant Cu, Zn superoxide dismu ...... ent in mitochondria in the CNS
@en
Mutant Cu, Zn superoxide dismu ...... ent in mitochondria in the CNS
@nl
type
label
Mutant Cu, Zn superoxide dismu ...... ent in mitochondria in the CNS
@ast
Mutant Cu, Zn superoxide dismu ...... ent in mitochondria in the CNS
@en
Mutant Cu, Zn superoxide dismu ...... ent in mitochondria in the CNS
@nl
prefLabel
Mutant Cu, Zn superoxide dismu ...... ent in mitochondria in the CNS
@ast
Mutant Cu, Zn superoxide dismu ...... ent in mitochondria in the CNS
@en
Mutant Cu, Zn superoxide dismu ...... ent in mitochondria in the CNS
@nl
P2093
P1476
Mutant Cu, Zn superoxide dismu ...... ent in mitochondria in the CNS
@en
P2093
Cheolwha Jung
Cynthia M J Higgins
Hongliu Ding
Zuoshang Xu
P356
10.1523/JNEUROSCI.22-06-J0001.2002
P407
P577
2002-03-01T00:00:00Z