Inactivation of the p34cdc2-cyclin B complex by the human WEE1 tyrosine kinase
about
Cooperative and individualistic functions of the microRNAs in the miR-23a~27a~24-2 cluster and its implication in human diseasesCyclin B1-Cdk1 activation continues after centrosome separation to control mitotic progressionOverproduction of human Myt1 kinase induces a G2 cell cycle delay by interfering with the intracellular trafficking of Cdc2-cyclin B1 complexesp53 regulation of G(2) checkpoint is retinoblastoma protein dependentPhosphorylation of WASP by the Cdc42-associated kinase ACK1: dual hydroxyamino acid specificity in a tyrosine kinaseTAO kinases mediate activation of p38 in response to DNA damageThe human Myt1 kinase preferentially phosphorylates Cdc2 on threonine 14 and localizes to the endoplasmic reticulum and Golgi complexCDK1 promotes cell proliferation and survival via phosphorylation and inhibition of FOXO1 transcription factorCell cycle regulation of human WEE1PPM1D dephosphorylates Chk1 and p53 and abrogates cell cycle checkpointsThe p53-inducible TSAP6 gene product regulates apoptosis and the cell cycle and interacts with Nix and the Myt1 kinaseCdc25M2 activation of cyclin-dependent kinases by dephosphorylation of threonine-14 and tyrosine-15Regulation of the human WEE1Hu CDK tyrosine 15-kinase during the cell cycleThe Saccharomyces cerevisiae checkpoint gene BUB1 encodes a novel protein kinaseUltrasensitivity in the Regulation of Cdc25C by Cdk1Mechanisms of G2 arrest in response to overexpression of p53Targeting the Checkpoint to Kill Cancer CellsCircadian disruption and breast cancer: an epigenetic link?Targeting cyclin-dependent kinases in human cancers: from small molecules to Peptide inhibitorsEmerging Treatment Paradigms in Radiation OncologyChanges in oscillatory dynamics in the cell cycle of early Xenopus laevis embryosHow Does the Xenopus laevis Embryonic Cell Cycle Avoid Spatial Chaos?A haploid genetic screen identifies the G1/S regulatory machinery as a determinant of Wee1 inhibitor sensitivity.SPK1 is an essential S-phase-specific gene of Saccharomyces cerevisiae that encodes a nuclear serine/threonine/tyrosine kinase.Cell cycle checkpoint in cancer: a therapeutically targetable double-edged swordYeast homolog of human SAG/ROC2/Rbx2/Hrt2 is essential for cell growth, but not for germination: chip profiling implicates its role in cell cycle regulationThe Chk1 protein kinase and the Cdc25C regulatory pathways are targets of the anticancer agent UCN-01A mammalian homolog of fission yeast Cdc5 regulates G2 progression and mitotic entryDephosphorylation of human p34cdc2 kinase on both Thr-14 and Tyr-15 by human cdc25B phosphataseFunctional association of TGF-beta receptor II with cyclin BThe protein-tyrosine kinase Lck associates with and is phosphorylated by Cdc2Identifying causal genes and dysregulated pathways in complex diseasesIsocorydine inhibits cell proliferation in hepatocellular carcinoma cell lines by inducing G2/m cell cycle arrest and apoptosisCdc25A is a novel phosphatase functioning early in the cell cycleEmbryonic poly(A)-binding protein (EPAB) is required for oocyte maturation and female fertility in miceCytoplasmic localization of human cdc25C during interphase requires an intact 14-3-3 binding siteOverexpression of LIM and SH3 Protein 1 leading to accelerated G2/M phase transition contributes to enhanced tumourigenesis in oral cancerPhysical and functional interactions between Lyn and p34cdc2 kinases in irradiated human B-cell precursors.Extensive crosstalk between O-GlcNAcylation and phosphorylation regulates cytokinesisFine tuning the cell cycle: activation of the Cdk1 inhibitory phosphorylation pathway during mitotic exit.
P2860
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P2860
Inactivation of the p34cdc2-cyclin B complex by the human WEE1 tyrosine kinase
description
1992 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
1992 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Science
@fr
artículu científicu espublizáu en 1992
@ast
im September 1992 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 1992/09/25)
@sk
vědecký článek publikovaný v roce 1992
@cs
wetenschappelijk artikel (gepubliceerd op 1992/09/25)
@nl
наукова стаття, опублікована у вересні 1992
@uk
name
Inactivation of the p34cdc2-cyclin B complex by the human WEE1 tyrosine kinase
@ast
Inactivation of the p34cdc2-cyclin B complex by the human WEE1 tyrosine kinase
@en
Inactivation of the p34cdc2-cyclin B complex by the human WEE1 tyrosine kinase
@nl
type
label
Inactivation of the p34cdc2-cyclin B complex by the human WEE1 tyrosine kinase
@ast
Inactivation of the p34cdc2-cyclin B complex by the human WEE1 tyrosine kinase
@en
Inactivation of the p34cdc2-cyclin B complex by the human WEE1 tyrosine kinase
@nl
prefLabel
Inactivation of the p34cdc2-cyclin B complex by the human WEE1 tyrosine kinase
@ast
Inactivation of the p34cdc2-cyclin B complex by the human WEE1 tyrosine kinase
@en
Inactivation of the p34cdc2-cyclin B complex by the human WEE1 tyrosine kinase
@nl
P3181
P356
P1433
P1476
Inactivation of the p34cdc2-cyclin B complex by the human WEE1 tyrosine kinase
@en
P2093
H. Piwnica-Worms
L. L. Parker
P304
P3181
P356
10.1126/SCIENCE.1384126
P407
P577
1992-09-25T00:00:00Z