Mutation of the predicted p34cdc2 phosphorylation sites in NuMA impair the assembly of the mitotic spindle and block mitosis
about
Opposing motor activities are required for the organization of the mammalian mitotic spindle poleNuMA phosphorylation by CDK1 couples mitotic progression with cortical dynein functionCortical dynein and asymmetric membrane elongation coordinately position the spindle in anaphaseCell cycle-regulated membrane binding of NuMA contributes to efficient anaphase chromosome separation.NuMA localization, stability, and function in spindle orientation involve 4.1 and Cdk1 interactions.Mitotic regulation of protein 4.1R involves phosphorylation by cdc2 kinaseComprehensive analysis of NuMA variation in breast cancer.NuMA is required for proper spindle assembly and chromosome alignment in prometaphase.Targeting the cyclin E-Cdk-2 complex represses lung cancer growth by triggering anaphase catastropheNuMA after 30 years: the matrix revisited.Tumor antigen acrosin binding protein normalizes mitotic spindle function to promote cancer cell proliferation.Plk1 regulates the kinesin-13 protein Kif2b to promote faithful chromosome segregation.CDK1 inactivation regulates anaphase spindle dynamics and cytokinesis in vivoSpindle assembly in Xenopus egg extracts: respective roles of centrosomes and microtubule self-organizationQuantitative phosphoproteomics identifies substrates and functional modules of Aurora and Polo-like kinase activities in mitotic cellsOn the inscrutable role of Inscuteable: structural basis and functional implications for the competitive binding of NuMA and Inscuteable to LGN.Cyclin B degradation leads to NuMA release from dynein/dynactin and from spindle poles.Self assembly of NuMA: multiarm oligomers as structural units of a nuclear lattice.Exclusive destruction of mitotic spindles in human cancer cells.NuMA is required for the organization of microtubules into aster-like mitotic arrays.NuMA recruits dynein activity to microtubule minus-ends at mitosis.The nuclear mitotic apparatus protein NuMA controls rDNA transcription and mediates the nucleolar stress response in a p53-independent manner.CCNB1:p-T160-CDK1 phosphorylates NUMA1Translocation of NuMA to the centrosomesG2/M transition of pig oocytes: How do oocytes initiate maturation?Dynein-Dynactin-NuMA clusters generate cortical spindle-pulling forces as a multi-arm ensemblePlk1 regulates spindle orientation by phosphorylating NuMA in human cells
P2860
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P2860
Mutation of the predicted p34cdc2 phosphorylation sites in NuMA impair the assembly of the mitotic spindle and block mitosis
description
1995 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
1995 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 1995
@ast
im Februar 1995 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 1995/02/01)
@sk
vědecký článek publikovaný v roce 1995
@cs
wetenschappelijk artikel (gepubliceerd op 1995/02/01)
@nl
наукова стаття, опублікована в лютому 1995
@uk
مقالة علمية (نشرت في فبراير 1995)
@ar
name
Mutation of the predicted p34c ...... otic spindle and block mitosis
@ast
Mutation of the predicted p34c ...... otic spindle and block mitosis
@en
Mutation of the predicted p34c ...... otic spindle and block mitosis
@nl
type
label
Mutation of the predicted p34c ...... otic spindle and block mitosis
@ast
Mutation of the predicted p34c ...... otic spindle and block mitosis
@en
Mutation of the predicted p34c ...... otic spindle and block mitosis
@nl
prefLabel
Mutation of the predicted p34c ...... otic spindle and block mitosis
@ast
Mutation of the predicted p34c ...... otic spindle and block mitosis
@en
Mutation of the predicted p34c ...... otic spindle and block mitosis
@nl
P1476
Mutation of the predicted p34c ...... otic spindle and block mitosis
@en
P2093
P304
P407
P478
108 ( Pt 2)
P577
1995-02-01T00:00:00Z