RasGRP1 and RasGRP3 regulate B cell proliferation by facilitating B cell receptor-Ras signaling
about
Structural analysis of autoinhibition in the Ras-specific exchange factor RasGRP1Expression of sprouty2 inhibits B-cell proliferation and is epigenetically silenced in mouse and human B-cell lymphomasLipid rafts and B cell signalingUnusual interplay of two types of Ras activators, RasGRP and SOS, establishes sensitive and robust Ras activation in lymphocytesThe Immunomodulatory Functions of Diacylglycerol Kinase ζGenome-wide analysis reveals adaptation to high altitudes in Tibetan sheepA genome-wide association study identifies GRK5 and RASGRP1 as type 2 diabetes loci in Chinese Hans.Molecular characterization of in vivo adjuvant activity in ferrets vaccinated against influenza virusRegulation of RasGRP1 function in T cell development and activation by its unique tail domain.Upregulation of RASGRP3 expression in prostate cancer correlates with aggressive capabilities and predicts biochemical recurrence after radical prostatectomyDifferent populations of CD11b+ dendritic cells drive Th2 responses in the small intestine and colonDiacylglycerol kinase ζ limits B cell antigen receptor-dependent activation of ERK signaling to inhibit early antibody responsesThe Ras activator RasGRP3 mediates diabetes-induced embryonic defects and affects endothelial cell migration.RasGRP3 contributes to formation and maintenance of the prostate cancer phenotype.Molecular underpinning of B-cell anergy.RasGRP1, but not RasGRP3, is required for efficient thymic β-selection and ERK activation downstream of CXCR4Phorbol ester stimulation of RasGRP1 regulates the sodium-chloride cotransporter by a PKC-independent pathway.Ontology based molecular signatures for immune cell types via gene expression analysisGrb2 regulates B-cell maturation, B-cell memory responses and inhibits B-cell Ca2+ signalling.Regulation and Function of the RasGRP Family of Ras Activators in Blood CellsCD117+ Dendritic and Mast Cells Are Dependent on RasGRP4 to Function as Accessory Cells for Optimal Natural Killer Cell-Mediated Responses to Lipopolysaccharide.Coordinated loss of microRNA group causes defenseless signaling in malignant lymphoma.Dysregulation of RasGRP1 in rheumatoid arthritis and modulation of RasGRP3 as a biomarker of TNFα inhibitors.Phospholipase C-gamma2 and Vav cooperate within signaling microclusters to propagate B cell spreading in response to membrane-bound antigenThe RAS guanyl nucleotide-releasing protein RasGRP1 is involved in lymphatic development in zebrafish.Phospholipids: "greasing the wheels" of humoral immunityCa(2+) signaling in antigen receptor-activated B lymphocytes.N-methyl-substituted fluorescent DAG-indololactone isomers exhibit dramatic differences in membrane interactions and biological activityAutoantibody-Mediated Pulmonary Alveolar Proteinosis in Rasgrp1-Deficient Mice.RasGRP1 overexpression in the epidermis of transgenic mice contributes to tumor progression during multistage skin carcinogenesis.A proapoptotic signaling pathway involving RasGRP, Erk, and Bim in B cells.Rasgrp1 mutation increases naive T-cell CD44 expression and drives mTOR-dependent accumulation of Helios⁺ T cells and autoantibodies.RasGRP1 promotes amphetamine-induced motor behavior through a Rhes interaction network ("Rhesactome") in the striatum.Increased CD40 Ligation and Reduced BCR Signalling Leads to Higher IL-10 Production in B Cells From Tolerant Kidney Transplant Patients.The B-lymphoid Grb2 interaction code.The roles of Dok family adapters in immunoreceptor signaling.RasGRP3, a Ras activator, contributes to signaling and the tumorigenic phenotype in human melanoma.Besides an ITIM/SHP-1-dependent pathway, CD22 collaborates with Grb2 and plasma membrane calcium-ATPase in an ITIM/SHP-1-independent pathway of attenuation of Ca2+i signal in B cells.Systemic Lupus Erythematosus: Old and New Susceptibility Genes versus Clinical Manifestations.Regulation of ras exchange factors and cellular localization of ras activation by lipid messengers in T cells.
P2860
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P2860
RasGRP1 and RasGRP3 regulate B cell proliferation by facilitating B cell receptor-Ras signaling
description
2005 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2005
@ast
im Dezember 2005 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2005/12/01)
@sk
vědecký článek publikovaný v roce 2005
@cs
wetenschappelijk artikel (gepubliceerd op 2005/12/01)
@nl
наукова стаття, опублікована в грудні 2005
@uk
مقالة علمية (نشرت في ديسمبر 2005)
@ar
name
RasGRP1 and RasGRP3 regulate B ...... B cell receptor-Ras signaling
@ast
RasGRP1 and RasGRP3 regulate B ...... B cell receptor-Ras signaling
@en
RasGRP1 and RasGRP3 regulate B ...... B cell receptor-Ras signaling
@nl
type
label
RasGRP1 and RasGRP3 regulate B ...... B cell receptor-Ras signaling
@ast
RasGRP1 and RasGRP3 regulate B ...... B cell receptor-Ras signaling
@en
RasGRP1 and RasGRP3 regulate B ...... B cell receptor-Ras signaling
@nl
prefLabel
RasGRP1 and RasGRP3 regulate B ...... B cell receptor-Ras signaling
@ast
RasGRP1 and RasGRP3 regulate B ...... B cell receptor-Ras signaling
@en
RasGRP1 and RasGRP3 regulate B ...... B cell receptor-Ras signaling
@nl
P2093
P3181
P1476
RasGRP1 and RasGRP3 regulate B ...... B cell receptor-Ras signaling
@en
P2093
James C. Stone
Jason J. Coughlin
Nancy A. Dower
Stacey L. Stang
P304
P3181
P356
10.4049/JIMMUNOL.175.11.7179
P407
P577
2005-12-01T00:00:00Z