Phosphorylation of the transcription factor NFATp inhibits its DNA binding activity in cyclosporin A-treated human B and T cells
about
Essential role of ROS-mediated NFAT activation in TNF-alpha induction by crystalline silica exposureCharacterization of a new isoform of the NFAT (nuclear factor of activated T cells) gene family member NFATcRecombinant NFAT1 (NFATp) is regulated by calcineurin in T cells and mediates transcription of several cytokine genesExpression of NFAT-family proteins in normal human T cellsControl of NFATx1 nuclear translocation by a calcineurin-regulated inhibitory domainCalcineurin-dependent nuclear translocation of a murine transcription factor NFATx: molecular cloning and functional characterizationCalcineurin binds the transcription factor NFAT1 and reversibly regulates its activityInteraction of calcineurin with a domain of the transcription factor NFAT1 that controls nuclear importRegulation of FOXC1 stability and transcriptional activity by an epidermal growth factor-activated mitogen-activated protein kinase signaling cascadeGlycogen synthase kinase-3 inhibits the DNA binding activity of NFATc.Calcineurin. Structure, function, and inhibition.NFAT and CREB regulate Kaposi's sarcoma-associated herpesvirus-induced cyclooxygenase 2 (COX-2)Immunosuppressive drugs prevent a rapid dephosphorylation of transcription factor NFAT1 in stimulated immune cellsRegulated nuclear localization of stress-responsive factors: how the nuclear trafficking of protein kinases and transcription factors contributes to cell survival.Induction of endoplasmic reticulum calcium pump expression during early leukemic B cell differentiation.Partners in transcription: NFAT and AP-1.The calcium/calmodulin-dependent protein phosphatase calcineurin is the major Elk-1 phosphatase.Calcineurin-dependent regulation of Crz1p nuclear export requires Msn5p and a conserved calcineurin docking site.Calcineurin phosphatase activity and immunosuppression. A review on the role of calcineurin phosphatase activity and the immunosuppressive effect of cyclosporin A and tacrolimus.Fibroblast growth factor receptor-1 interacts with the T-cell receptor signalling pathway.The Wnt5A/protein kinase C pathway mediates motility in melanoma cells via the inhibition of metastasis suppressors and initiation of an epithelial to mesenchymal transition.KARP-1 is induced by DNA damage in a p53- and ataxia telangiectasia mutated-dependent fashion.Akirin2 regulates proliferation and differentiation of porcine skeletal muscle satellite cells via ERK1/2 and NFATc1 signaling pathways.Role in calcineurin inhibitors for inflammatory bowel disease in the biologics era: when and how to use.Vascular endothelial growth factor activates nuclear factor of activated T cells in human endothelial cells: a role for tissue factor gene expression.T-cell receptor stimulation elicits an early phase of activation and a later phase of deactivation of the transcription factor NFAT1.Overexpression of c-myc in pancreatic cancer caused by ectopic activation of NFATc1 and the Ca2+/calcineurin signaling pathway.The therapeutic potential of targeting drugs at transcription factors.Protein kinase A negatively modulates the nuclear accumulation of NF-ATc1 by priming for subsequent phosphorylation by glycogen synthase kinase-3.NFATc1 as a therapeutic target in FLT3-ITD-positive AML.Involvement of NF-AT in type I human T-cell leukemia virus Tax-mediated Fas ligand promoter transactivation.Nucleocytoplasmic shuttling factors including Ran and CRM1 mediate nuclear export of NFAT In vitrop53 transactivation of the HIV-1 long terminal repeat is blocked by PD 144795, a calcineurin-inhibitor with anti-HIV properties.Evidence for cyclin D3 as a novel target of rapamycin in human T lymphocytes.Pancreatic β-Cell-Derived IP-10/CXCL10 Isletokine Mediates Early Loss of Graft Function in Islet Cell Transplantation.Constitutive dephosphorylation and activation of a member of the nuclear factor of activated T cells, NF-AT1, in Tax-expressing and type I human T-cell leukemia virus-infected human T cells.NFATc2 Modulates Microglial Activation in the AβPP/PS1 Mouse Model of Alzheimer's Disease.Calcineurin dephosphorylates NFATC1;2;3
P2860
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P2860
Phosphorylation of the transcription factor NFATp inhibits its DNA binding activity in cyclosporin A-treated human B and T cells
description
1995 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
1995 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Journal of Biological Chemistry
@fr
artículu científicu espublizáu en 1995
@ast
im September 1995 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 1995/09/01)
@sk
vědecký článek publikovaný v roce 1995
@cs
wetenschappelijk artikel (gepubliceerd op 1995/09/01)
@nl
наукова стаття, опублікована у вересні 1995
@uk
name
Phosphorylation of the transcr ...... A-treated human B and T cells
@ast
Phosphorylation of the transcr ...... A-treated human B and T cells
@en
Phosphorylation of the transcr ...... A-treated human B and T cells
@nl
type
label
Phosphorylation of the transcr ...... A-treated human B and T cells
@ast
Phosphorylation of the transcr ...... A-treated human B and T cells
@en
Phosphorylation of the transcr ...... A-treated human B and T cells
@nl
prefLabel
Phosphorylation of the transcr ...... A-treated human B and T cells
@ast
Phosphorylation of the transcr ...... A-treated human B and T cells
@en
Phosphorylation of the transcr ...... A-treated human B and T cells
@nl
P2093
P2860
P356
P1476
Phosphorylation of the transcr ...... A-treated human B and T cells
@en
P2093
P2860
P304
20653–20659
P356
10.1074/JBC.270.35.20653
P407
P577
1995-09-01T00:00:00Z