Phosphorylation of acyclovir (acycloguanosine) monophosphate by GMP kinase
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Identification of eIF2Bgamma and eIF2gamma as cofactors of hepatitis C virus internal ribosome entry site-mediated translation using a functional genomics approachThe anti-hepatitis B virus activities, cytotoxicities, and anabolic profiles of the (-) and (+) enantiomers of cis-5-fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]cytosineEfficacies of antiherpesvirus nucleosides against two strains of herpes simplex virus type 1 in Vero and human embryo lung fibroblast cellsMode of action, toxicity, pharmacokinetics, and efficacy of some new antiherpesvirus guanosine analogs related to buciclovirEffect of ganciclovir [9-(1,3-dihydroxy-2-propoxymethyl)guanine] on viral DNA and protein synthesis in cells infected with herpes simplex virusEfficacy of acyclovir against mouse cytomegalovirus in vivo9-([2-hydroxy-1-(hydroxymethyl)ethoxy]methyl)guanine: a selective inhibitor of herpes group virus replicationMode of action of (1'S,2'R)-9-[[1',2'-bis(hydroxymethyl) cycloprop-1'-yl]methyl]guanine (A-5021) against herpes simplex virus type 1 and type 2 and varicella-zoster virus.Characterization of herpes simplex virus type 1 thymidine kinase mutants engineered for improved ganciclovir or acyclovir activity.Fusion enzymes containing HSV-1 thymidine kinase mutants and guanylate kinase enhance prodrug sensitivity in vitro and in vivo.Influence of acyclovir and bucyclovir on nucleotide pools in cells infected with herpes simplex virus type 1.Resistance of herpes simplex viruses to nucleoside analogues: mechanisms, prevalence, and managementEnzyme closure and nucleotide binding structurally lock guanylate kinase.Phosphorylation of acyclovir [9-(2-hydroxyethoxymethyl)guanine] in Epstein-Barr virus-infected lymphoblastoid cell linesEffects of ribonucleotide reductase inhibition on pyrimidine deoxynucleotide metabolism in acyclovir-treated cells infected with herpes simplex virus type 1Resistance of herpesviruses to antiviral drugsAntiviral activities of guanosine analogs in guinea pig embryonic fibroblastsUptake, distribution, and anabolism of acyclovir in herpes simplex virus-infected micePhosphorylation of acyclovir in vitro in activated Burkitt somatic cell hybrids.Antiviral therapy: current concepts and practicesAcyclovir diphosphate dimyristoylglycerol: a phospholipid prodrug with activity against acyclovir-resistant herpes simplex virus.Acyclovir-resistant mutants of herpes simplex virus type 1 express altered DNA polymerase or reduced acyclovir phosphorylating activities.Mutations at serine 37 in mouse guanylate kinase confer resistance to 6-thioguanine.The application of phosphoramidate protide technology to acyclovir confers anti-HIV inhibition.Mechanisms associated with HIV-1 resistance to acyclovir by the V75I mutation in reverse transcriptase.Productive versus unproductive nucleotide binding in yeast guanylate kinase mutants: comparison of R41M with K14M by proton two dimensional transferred NOESY.Creation of drug-specific herpes simplex virus type 1 thymidine kinase mutants for gene therapy.Potentiation of antiherpetic activity of acyclovir by ribonucleotide reductase inhibitionPhosphorylation events during viral infections provide potential therapeutic targets.Kinetics of the interaction of monophosphates of the antiviral nucleosides 2'-fluoro-1-beta-D-arabinofuranosylpyrimidine and (E)-5-(2-bromovinyl)-2'-deoxyuridine with thymidylate kinases from Vero cells and herpes simplex virus types 1 and 2.Plaque autoradiography assay for the detection and quantitation of thymidine kinase-deficient and thymidine kinase-altered mutants of herpes simplex virus in clinical isolates.Metabolism of acyclovir in virus-infected and uninfected cells.Herpes simplex virus type 1 prereplicative sites are a heterogeneous population: only a subset are likely to be precursors to replication compartments.Specific targets for antiviral drugs.Genetic analysis of the susceptibility of mouse cytomegalovirus to acyclovir.Properties of a novel thymidine kinase induced by an acyclovir-resistant herpes simplex virus type 1 mutant.Effects of Acyclovir, Foscarnet, and Ribonucleotides on Herpes Simplex Virus-1 DNA Polymerase: Mechanistic Insights and a Novel Mechanism for Preventing Stable Incorporation of Ribonucleotides into DNA.Novel multipurpose pod-intravaginal ring for the prevention of HIV, HSV, and unintended pregnancy: Pharmacokinetic evaluation in a macaque modelA novel mouse model of depletion of stellate cells clarifies their role in ischemia/reperfusion- and endotoxin-induced acute liver injury.Stereoselective phosphorylation of cyclopropavir by pUL97 and competitive inhibition by maribavir.
P2860
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P2860
Phosphorylation of acyclovir (acycloguanosine) monophosphate by GMP kinase
description
1980 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
1980 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Journal of Biological Chemistry
@fr
artículu científicu espublizáu en 1980
@ast
im August 1980 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 1980/08/10)
@sk
vědecký článek publikovaný v roce 1980
@cs
wetenschappelijk artikel (gepubliceerd op 1980/08/10)
@nl
наукова стаття, опублікована в серпні 1980
@uk
name
Phosphorylation of acyclovir (acycloguanosine) monophosphate by GMP kinase
@ast
Phosphorylation of acyclovir (acycloguanosine) monophosphate by GMP kinase
@en
Phosphorylation of acyclovir (acycloguanosine) monophosphate by GMP kinase
@nl
type
label
Phosphorylation of acyclovir (acycloguanosine) monophosphate by GMP kinase
@ast
Phosphorylation of acyclovir (acycloguanosine) monophosphate by GMP kinase
@en
Phosphorylation of acyclovir (acycloguanosine) monophosphate by GMP kinase
@nl
prefLabel
Phosphorylation of acyclovir (acycloguanosine) monophosphate by GMP kinase
@ast
Phosphorylation of acyclovir (acycloguanosine) monophosphate by GMP kinase
@en
Phosphorylation of acyclovir (acycloguanosine) monophosphate by GMP kinase
@nl
P1476
Phosphorylation of acyclovir (acycloguanosine) monophosphate by GMP kinase
@en
P2093
R L Miller
W H Miller
P304
P407
P577
1980-08-01T00:00:00Z