Acetylation of human prostaglandin endoperoxide synthase-2 (cyclooxygenase-2) by aspirin
about
Aspirin triggers previously undescribed bioactive eicosanoids by human endothelial cell-leukocyte interactionsIdentification and absolute configuration of dihydroxy-arachidonic acids formed by oxygenation of 5S-HETE by native and aspirin-acetylated COX-2Carbocations in the synthesis of prostaglandins by the cyclooxygenase of PGH synthase? A radical departure!A fluorescence microscopy method for quantifying the detection of prostaglandin endoperoxide H synthase-1 and CD-41 in MEG-01 cellsStructural Basis of Fatty Acid Substrate Binding to Cyclooxygenase-2Release of tumor necrosis factor-alpha and prostanoids in whole blood cultures after in vivo exposure to low-dose aspirinDiscovery of a new function of cyclooxygenase (COX)-2: COX-2 is a cardioprotective protein that alleviates ischemia/reperfusion injury and mediates the late phase of preconditioningMolecular dynamics simulations of arachidonic acid complexes with COX-1 and COX-2: insights into equilibrium behaviorEvidence that 5-lipoxygenase and acetylated cyclooxygenase 2-derived eicosanoids regulate leukocyte-endothelial adherence in response to aspirinCOX-2-dependent and -independent biosynthesis of dihydroxy-arachidonic acids in activated human leukocytesBiosynthesis, biological effects, and receptors of hydroxyeicosatetraenoic acids (HETEs) and oxoeicosatetraenoic acids (oxo-ETEs) derived from arachidonic acidA three-step kinetic mechanism for selective inhibition of cyclo-oxygenase-2 by diarylheterocyclic inhibitorsStructural basis for certain naturally occurring bioflavonoids to function as reducing co-substrates of cyclooxygenase I and IIOxygenation by COX-2 (cyclo-oxygenase-2) of 3-HETE (3-hydroxyeicosatetraenoic acid), a fungal mimetic of arachidonic acid, produces a cascade of novel bioactive 3-hydroxyeicosanoidsSpecialized pro-resolving lipid mediators in the inflammatory response: An updateAsymmetric acetylation of the cyclooxygenase-2 homodimer by aspirin and its effects on the oxygenation of arachidonic, eicosapentaenoic, and docosahexaenoic acids.Plasma prostaglandin E2 concentrations after single dose administration of ketorolac tromethamine (Toradol) in dogsThe origin of 15R-prostaglandins in the Caribbean coral Plexaura homomalla: molecular cloning and expression of a novel cyclooxygenase.The mode of action of aspirin-like drugs: effect on inducible nitric oxide synthase.Phospholipase A2 regulates eicosanoid class switching during inflammasome activationPharmacologic considerations in the treatment of injured athletes with nonsteroidal anti-inflammatory drugs.Anti-inflammatory function of arctiin by inhibiting COX-2 expression via NF-κB pathways.Problem of the atherothrombotic potential of non-steroidal anti-inflammatory drugs.Augmented expression of cyclooxygenase-2 in human atherosclerotic lesions.Applications of stereospecifically-labeled Fatty acids in oxygenase and desaturase biochemistryLow-dose aspirin (acetylsalicylate) prevents increases in brain PGE2, 15-epi-lipoxin A4 and 8-isoprostane concentrations in 9 month-old HIV-1 transgenic rats, a model for HIV-1 associated neurocognitive disorders.Emerging roles for cyclooxygenase-2 in gastrointestinal mucosal defense.Synthesis of 7-thiaarachidonic acid as a mechanistic probe of prostaglandin H synthase-2.Cyclooxygenase-2 and its regulation in inflammation.Crystal Structure of Aspirin-Acetylated Human Cyclooxygenase-2: Insight into the Formation of Products with Reversed Stereochemistry.Control of oxygenation in lipoxygenase and cyclooxygenase catalysisPre-existent asymmetry in the human cyclooxygenase-2 sequence homodimer.Acetylation of prostaglandin H2 synthases by aspirin is inhibited by redox cycling of the peroxidase.Aspirin-induced Bcl-2 translocation and its phosphorylation in the nucleus trigger apoptosis in breast cancer cellsGrape Seed Extract Attenuates Hepatitis C Virus Replication and Virus-Induced Inflammation.Polyunsaturated Fatty Acid-derived lipid mediators and T cell function.Cyclooxygenase-2 Mediated Oxidation of 2-Arachidonoyl-Lysophospholipids Identifies Unknown Lipid Signaling Pathways.Cyclooxygenase-2 catalysis and inhibition in lipid bilayer nanodiscsAspirin Suppresses Growth in PI3K-Mutant Breast Cancer by Activating AMPK and Inhibiting mTORC1 Signaling.Acetylsalicylic acid (aspirin) reduces damage to reconstituted human tissues infected with Candida species by inhibiting extracellular fungal lipases
P2860
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P2860
Acetylation of human prostaglandin endoperoxide synthase-2 (cyclooxygenase-2) by aspirin
description
1994 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
1994 թվականի մայիսին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Journal of Biological Chemistry
@fr
artículu científicu espublizáu en 1994
@ast
im Mai 1994 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 1994/05/06)
@sk
vědecký článek publikovaný v roce 1994
@cs
wetenschappelijk artikel (gepubliceerd op 1994/05/06)
@nl
наукова стаття, опублікована в травні 1994
@uk
name
Acetylation of human prostaglandin endoperoxide synthase-2 (cyclooxygenase-2) by aspirin
@ast
Acetylation of human prostaglandin endoperoxide synthase-2 (cyclooxygenase-2) by aspirin
@en
Acetylation of human prostaglandin endoperoxide synthase-2 (cyclooxygenase-2) by aspirin
@nl
type
label
Acetylation of human prostaglandin endoperoxide synthase-2 (cyclooxygenase-2) by aspirin
@ast
Acetylation of human prostaglandin endoperoxide synthase-2 (cyclooxygenase-2) by aspirin
@en
Acetylation of human prostaglandin endoperoxide synthase-2 (cyclooxygenase-2) by aspirin
@nl
prefLabel
Acetylation of human prostaglandin endoperoxide synthase-2 (cyclooxygenase-2) by aspirin
@ast
Acetylation of human prostaglandin endoperoxide synthase-2 (cyclooxygenase-2) by aspirin
@en
Acetylation of human prostaglandin endoperoxide synthase-2 (cyclooxygenase-2) by aspirin
@nl
P2093
P3181
P1476
Acetylation of human prostaglandin endoperoxide synthase-2 (cyclooxygenase-2) by aspirin
@en
P2093
D. L. DeWitt
M. Lecomte
O. Laneuville
W. L. Smith
P304
13207–13215
P3181
P407
P577
1994-05-06T00:00:00Z