Further studies on the reconstitution of glucosylceramidase activity by Sap C and anionic phospholipids

Further studies on the reconstitution of glucosylceramidase activity by Sap C and anionic phospholipids

Item
http://www.wikidata.org/entity/Q28631613
Crystal structures of saposins A and CReduced cathepsins B and D cause impaired autophagic degradation that can be almost completely restored by overexpression of these two proteases in Sap C-deficient fibroblastsGlucosylceramidase mass and subcellular localization are modulated by cholesterol in Niemann-Pick disease type C.Biosynthesis and degradation of mammalian glycosphingolipids.Saposins utilize two strategies for lipid transfer and CD1 antigen presentationGlucocerebrosidase activity in Parkinson's disease with and without GBA mutationsThe N370S (Asn370-->Ser) mutation affects the capacity of glucosylceramidase to interact with anionic phospholipid-containing membranes and saposin CMembrane lipids regulate ganglioside GM2 catabolism and GM2 activator protein activityInteraction of saposin D with membranes: effect of anionic phospholipids and sphingolipids.Saposin C mutations in Gaucher disease patients resulting in lysosomal lipid accumulation, saposin C deficiency, but normal prosaposin processing and sorting.Saposin B binds and transfers phospholipids.Glucosylceramidase cleaves the glucosidic bond of glucocerebroside to form ceramide
P2860

Further studies on the reconstitution of glucosylceramidase activity by Sap C and anionic phospholipids

Item
http://www.wikidata.org/entity/Q28631613
description
2000 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2000
@ast
im April 2000 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2000/04/21)
@sk
vědecký článek publikovaný v roce 2000
@cs
wetenschappelijk artikel (gepubliceerd op 2000/04/21)
@nl
наукова стаття, опублікована у квітні 2000
@uk
مقالة علمية (نشرت في 21-4-2000)
@ar
name
Further studies on the reconst ...... ap C and anionic phospholipids
@ast
Further studies on the reconst ...... ap C and anionic phospholipids
@en
Further studies on the reconst ...... ap C and anionic phospholipids
@nl
type
label
Further studies on the reconst ...... ap C and anionic phospholipids
@ast
Further studies on the reconst ...... ap C and anionic phospholipids
@en
Further studies on the reconst ...... ap C and anionic phospholipids
@nl
prefLabel
Further studies on the reconst ...... ap C and anionic phospholipids
@ast
Further studies on the reconst ...... ap C and anionic phospholipids
@en
Further studies on the reconst ...... ap C and anionic phospholipids
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
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P478
P577
P5875
P698
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P1433
P1476
Further studies on the reconst ...... ap C and anionic phospholipids
@en
P2093
P2860
P304
P31
P356
10.1016/S0014-5793(00)01417-4
P407
P433
P478
P577
P5875
P698