Gli2, but not Gli1, is required for initial Shh signaling and ectopic activation of the Shh pathway
about
Activation of the Hedgehog signaling pathway in T-lineage cells inhibits TCR repertoire selection in the thymus and peripheral T-cell activationMediator modulates Gli3-dependent Sonic hedgehog signalingA potential role of alternative splicing in the regulation of the transcriptional activity of human GLI2 in gonadal tissues.The Talpid3 gene (KIAA0586) encodes a centrosomal protein that is essential for primary cilia formationDual function of UNC-51-like kinase 3 (Ulk3) in the Sonic hedgehog signaling pathwayMice deficient in the fused homolog do not exhibit phenotypes indicative of perturbed hedgehog signaling during embryonic developmentGli proteins and the control of spinal-cord patterningA gradient of Gli activity mediates graded Sonic Hedgehog signaling in the neural tubeMIM/BEG4, a Sonic hedgehog-responsive gene that potentiates Gli-dependent transcriptionThe Engrailed homeobox genes determine the different foliation patterns in the vermis and hemispheres of the mammalian cerebellum.The hedgehog pathway in triple-negative breast cancerKey Fibrogenic SignalingThe potential origin of glioblastoma initiating cellsIFT27 links the BBSome to IFT for maintenance of the ciliary signaling compartment.Stromal Hedgehog signalling is downregulated in colon cancer and its restoration restrains tumour growth.Genetic tools for identifying and manipulating fibroblasts in the mouseMouse hitchhiker mutants have spina bifida, dorso-ventral patterning defects and polydactyly: identification of Tulp3 as a novel negative regulator of the Sonic hedgehog pathwaySonic hedgehog signaling regulates Gli2 transcriptional activity by suppressing its processing and degradationThe transcription factor Gli3 regulates differentiation of fetal CD4- CD8- double-negative thymocytes.Phosphorylation of Gli2 by protein kinase A is required for Gli2 processing and degradation and the Sonic Hedgehog-regulated mouse developmentForward genetics uncovers Transmembrane protein 107 as a novel factor required for ciliogenesis and Sonic hedgehog signalingAP-2alpha knockout mice exhibit optic cup patterning defects and failure of optic stalk morphogenesisTubby-like protein 3 (TULP3) regulates patterning in the mouse embryo through inhibition of Hedgehog signalingSonic hedgehog negatively regulates pre-TCR-induced differentiation by a Gli2-dependent mechanismGLI3 repressor controls nephron number via regulation of Wnt11 and Ret in ureteric tip cellsGATA6 is a crucial regulator of Shh in the limb budCilium-independent regulation of Gli protein function by Sufu in Hedgehog signaling is evolutionarily conservedIncreased hedgehog signaling in postnatal kidney results in aberrant activation of nephron developmental programsGas1 is a modifier for holoprosencephaly and genetically interacts with sonic hedgehogThe trafficking protein Tmed2/p24beta(1) is required for morphogenesis of the mouse embryo and placentaThe Shh-independent activator function of the full-length Gli3 protein and its role in vertebrate limb digit patterningGli1 protein participates in Hedgehog-mediated specification of osteoblast lineage during endochondral ossificationProgenitor cell proliferation in the retina is dependent on Notch-independent Sonic hedgehog/Hes1 activityTankyrase 2 poly(ADP-ribose) polymerase domain-deleted mice exhibit growth defects but have normal telomere length and cappingThe expression of Gli3, regulated by HOXD13, may play a role in idiopathic congenital talipes equinovarusPersistent sonic hedgehog signaling in adult brain determines neural stem cell positional identity.Hedgehog/Wnt feedback supports regenerative proliferation of epithelial stem cells in bladderSonic hedgehog signals to multiple prostate stromal stem cells that replenish distinct stromal subtypes during regeneration.Coordinated translocation of mammalian Gli proteins and suppressor of fused to the primary ciliumHuman GLI3 intragenic conserved non-coding sequences are tissue-specific enhancers.
P2860
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P2860
Gli2, but not Gli1, is required for initial Shh signaling and ectopic activation of the Shh pathway
description
2002 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2002
@ast
im Oktober 2002 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2002/10/01)
@sk
vědecký článek publikovaný v roce 2002
@cs
wetenschappelijk artikel (gepubliceerd op 2002/10/01)
@nl
наукова стаття, опублікована в жовтні 2002
@uk
مقالة علمية (نشرت في أكتوبر 2002)
@ar
name
Gli2, but not Gli1, is require ...... activation of the Shh pathway
@ast
Gli2, but not Gli1, is require ...... activation of the Shh pathway
@en
Gli2, but not Gli1, is require ...... activation of the Shh pathway
@nl
type
label
Gli2, but not Gli1, is require ...... activation of the Shh pathway
@ast
Gli2, but not Gli1, is require ...... activation of the Shh pathway
@en
Gli2, but not Gli1, is require ...... activation of the Shh pathway
@nl
prefLabel
Gli2, but not Gli1, is require ...... activation of the Shh pathway
@ast
Gli2, but not Gli1, is require ...... activation of the Shh pathway
@en
Gli2, but not Gli1, is require ...... activation of the Shh pathway
@nl
P2093
P3181
P1433
P1476
Gli2, but not Gli1, is require ...... activation of the Shh pathway
@en
P2093
Alexandra L. Joyner
C. Brian Bai
Daniel Stephen
Joon S. Lee
Wojtek Auerbach
P304
P3181
P407
P577
2002-10-01T00:00:00Z