Identification of hyaluronan-binding domains of aggrecan
about
Structure and interactions of aggrecans: statistical thermodynamic approachDistinct interaction of versican/PG-M with hyaluronan and link proteinSubcellular distribution, calmodulin interaction, and mitochondrial association of the hyaluronan-binding protein RHAMM in rat brainLink protein has greater affinity for versican than aggrecanDevelopment of a peptide inhibitor of hyaluronan-mediated leukocyte trafficking.Expression and purification of functionally active hyaluronan-binding domains from human cartilage link protein, aggrecan and versican: formation of ternary complexes with defined hyaluronan oligosaccharides.Splicing factor 3b subunit 4 binds BMPR-IA and inhibits osteochondral cell differentiation.Synthesis rates and binding kinetics of matrix products in engineered cartilage constructs using chondrocyte-seeded agarose gels.Chondroitin sulfate proteoglycans: structure-function relationship with implication in neural development and brain disordersN-Glycans on the link domain of human HARE/Stabilin-2 are needed for hyaluronan binding to purified ecto-domain, but not for cellular endocytosis of hyaluronanStructure and function of aggrecan.Proteomic analysis of potential keratan sulfate, chondroitin sulfate A, and hyaluronic acid molecular interactions.The different roles of aggrecan interaction domainsTowards a structure for a TSG-6.hyaluronan complex by modeling and NMR spectroscopy: insights into other members of the link module superfamily.TSG-6 interacts with hyaluronan and aggrecan in a pH-dependent manner via a common functional element: implications for its regulation in inflamed cartilage.Involvement of ADAMTS5 and hyaluronidase in aggrecan degradation and release from OSM-stimulated cartilageHyaluronic acid-based nanocarriers for intracellular targeting: interfacial interactions with proteins in cancer.The role of aggrecan in normal and osteoarthritic cartilage.Extracellular superoxide dismutase inhibits inflammation by preventing oxidative fragmentation of hyaluronanHyaluronan: a simple polysaccharide with diverse biological functions.Mining the extracellular matrix for tissue engineering applications.Pathophysiology, diagnosis and prevention of arthropathy in patients with haemophilia.Recombinant production of proteoglycans and their bioactive domains.TM14 is a new member of the fibulin family (fibulin-7) that interacts with extracellular matrix molecules and is active for cell binding.Identification of a major heparin and cell binding site in the LG4 module of the laminin alpha 5 chain.Hyaluronan binding to link module of TSG-6 and to G1 domain of aggrecan is differently regulated by pH.Age-related changes in the composition, the molecular stoichiometry and the stability of proteoglycan aggregates extracted from human articular cartilage.Unbinding of hyaluronan accelerates the enzymatic activity of bee hyaluronidase.Antigen-specific B lymphocytes acquire proteoglycan aggrecan from cartilage extracellular matrix resulting in antigen presentation and CD4+ T-cell activation.Identity of urinary trypsin inhibitor-binding protein to link protein.Normal and shear interactions between hyaluronan-aggrecan complexes mimicking possible boundary lubricants in articular cartilage in synovial jointsRoles of aggrecan domains in biosynthesis, modification by glycosaminoglycans and product secretion.Mapping the hyaluronan-binding site on the link module from human tumor necrosis factor-stimulated gene-6 by site-directed mutagenesis.Direct quantification of the rupture force of single hyaluronan/hyaluronan binding protein bonds.Ophthalmic delivery of sparfloxacin from in situ gel formulation for treatment of experimentally induced bacterial keratitis.Single-Molecule Imaging of Proteoglycans in the Pericellular Matrix.Aggrecan binds Hyaluronan and HAPLN1Endocervical immune mediator production following successful rescue or ultrasound indicated cerclage placement.Identification and characterization of versican/PG-M aggregates in cartilage.
P2860
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P2860
Identification of hyaluronan-binding domains of aggrecan
description
1997 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Journal of Biological Chemistry
@fr
artículu científicu espublizáu en 1997
@ast
im Oktober 1997 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 1997/10/31)
@sk
vědecký článek publikovaný v roce 1997
@cs
wetenschappelijk artikel (gepubliceerd op 1997/10/31)
@nl
наукова стаття, опублікована в жовтні 1997
@uk
name
Identification of hyaluronan-binding domains of aggrecan
@ast
Identification of hyaluronan-binding domains of aggrecan
@en
Identification of hyaluronan-binding domains of aggrecan
@nl
type
label
Identification of hyaluronan-binding domains of aggrecan
@ast
Identification of hyaluronan-binding domains of aggrecan
@en
Identification of hyaluronan-binding domains of aggrecan
@nl
prefLabel
Identification of hyaluronan-binding domains of aggrecan
@ast
Identification of hyaluronan-binding domains of aggrecan
@en
Identification of hyaluronan-binding domains of aggrecan
@nl
P2093
P2860
P356
P1476
Identification of hyaluronan-binding domains of aggrecan
@en
P2093
H. Watanabe
S. C. Cheung
P2860
P304
28057–28065
P356
10.1074/JBC.272.44.28057
P407
P577
1997-10-31T00:00:00Z