Matrix metalloproteinase-3 releases active heparin-binding EGF-like growth factor by cleavage at a specific juxtamembrane site
about
Epilysin, a novel human matrix metalloproteinase (MMP-28) expressed in testis and keratinocytes and in response to injuryA metalloprotease-disintegrin, MDC9/meltrin-gamma/ADAM9 and PKCdelta are involved in TPA-induced ectodomain shedding of membrane-anchored heparin-binding EGF-like growth factor.N-arginine dibasic convertase is a specific receptor for heparin-binding EGF-like growth factor that mediates cell migration.Collagenase promotes the cellular responses to injury and wound healing in vivoSequential and gamma-secretase-dependent processing of the betacellulin precursor generates a palmitoylated intracellular-domain fragment that inhibits cell growthEctodomain shedding of epidermal growth factor receptor ligands is required for keratinocyte migration in cutaneous wound healingMatrix metalloproteinases in lung biologyMatrix metalloproteinases: old dogs with new tricksInsidious changes in stromal matrix fuel cancer progressionGenetic and teratogenic approaches to craniofacial developmentCleavage of metastasis suppressor gene product KiSS-1 protein/metastin by matrix metalloproteinasesSystemic biomarkers of neutrophilic inflammation, tissue injury and repair in COPD patients with differing levels of disease severityMatrix metalloproteinases and the regulation of tissue remodellingHow matrix metalloproteinases regulate cell behaviorMMP13 mediates cell cycle progression in melanocytes and melanoma cells: in vitro studies of migration and proliferation.Cleavage of syndecan-1 by membrane type matrix metalloproteinase-1 stimulates cell migration.Selective roles for tumor necrosis factor alpha-converting enzyme/ADAM17 in the shedding of the epidermal growth factor receptor ligand family: the juxtamembrane stalk determines cleavage efficiency.The bronchial epithelium as a key regulator of airway inflammation and remodelling in asthma.The stromal proteinase MMP3/stromelysin-1 promotes mammary carcinogenesis.The matrix metalloproteinase stromelysin-1 acts as a natural mammary tumor promoter.TAF4 inactivation in embryonic fibroblasts activates TGF beta signalling and autocrine growth.Expression, regulation and functional characterization of matrix metalloproteinase-3 of human trophoblast.Metalloproteinases and transforming growth factor-alpha mediate substance P-induced mitogen-activated protein kinase activation and proliferation in human colonocytes.ADAM10 mediates ectodomain shedding of the betacellulin precursor activated by p-aminophenylmercuric acetate and extracellular calcium influx.Transmodulation of cell surface regulatory molecules via ectodomain shedding.Protease-mediated human smooth muscle cell proliferation by urokinase requires epidermal growth factor receptor transactivation by triple membrane signaling.Metzincin proteases and their inhibitors: foes or friends in nervous system physiology?HB-EGF directs stromal cell polyploidy and decidualization via cyclin D3 during implantationDistinct mechanisms of receptor and nonreceptor tyrosine kinase activation by reactive oxygen species in vascular smooth muscle cells: role of metalloprotease and protein kinase C-deltaDiscovery of chemokine substrates for matrix metalloproteinases by exosite scanning: a new tool for degradomics.CD44 anchors the assembly of matrilysin/MMP-7 with heparin-binding epidermal growth factor precursor and ErbB4 and regulates female reproductive organ remodelingMT-MMPS as Regulators of Vessel Stability Associated with AngiogenesisDefective valvulogenesis in HB-EGF and TACE-null mice is associated with aberrant BMP signaling.ADAM12 is selectively overexpressed in human glioblastomas and is associated with glioblastoma cell proliferation and shedding of heparin-binding epidermal growth factorInterplay of host microbiota, genetic perturbations, and inflammation promotes local development of intestinal neoplasms in miceThe mitogenic potential of heparin-binding epidermal growth factor in the human endometrium is mediated by the epidermal growth factor receptor and is modulated by tumor necrosis factor-alpha.Mechanism and its regulation of tumor-induced angiogenesis.Mechanotransduction of extracellular signal-regulated kinases 1 and 2 mitogen-activated protein kinase activity in smooth muscle is dependent on the extracellular matrix and regulated by matrix metalloproteinasesMatrix metalloproteinase-2 is required for the switch to the angiogenic phenotype in a tumor modelA secreted MMP is required for reepithelialization during wound healing
P2860
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P2860
Matrix metalloproteinase-3 releases active heparin-binding EGF-like growth factor by cleavage at a specific juxtamembrane site
description
1997 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Journal of Biological Chemistry
@fr
artículu científicu espublizáu en 1997
@ast
im Dezember 1997 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 1997/12/12)
@sk
vědecký článek publikovaný v roce 1997
@cs
wetenschappelijk artikel (gepubliceerd op 1997/12/12)
@nl
наукова стаття, опублікована в грудні 1997
@uk
name
Matrix metalloproteinase-3 rel ...... a specific juxtamembrane site
@ast
Matrix metalloproteinase-3 rel ...... a specific juxtamembrane site
@en
Matrix metalloproteinase-3 rel ...... a specific juxtamembrane site
@nl
type
label
Matrix metalloproteinase-3 rel ...... a specific juxtamembrane site
@ast
Matrix metalloproteinase-3 rel ...... a specific juxtamembrane site
@en
Matrix metalloproteinase-3 rel ...... a specific juxtamembrane site
@nl
prefLabel
Matrix metalloproteinase-3 rel ...... a specific juxtamembrane site
@ast
Matrix metalloproteinase-3 rel ...... a specific juxtamembrane site
@en
Matrix metalloproteinase-3 rel ...... a specific juxtamembrane site
@nl
P2093
P356
P1476
Matrix metalloproteinase-3 rel ...... a specific juxtamembrane site
@en
P2093
C. A. Fernandez
M. A. Moses
M. Klagsbrun
P304
31730–31737
P356
10.1074/JBC.272.50.31730
P407
P577
1997-12-12T00:00:00Z