Sterol regulatory element-binding protein-1 as a key transcription factor for nutritional induction of lipogenic enzyme genes - Wikidata - wikimedia - TriplyDB

Sterol regulatory element-binding protein-1 as a key transcription factor for nutritional induction of lipogenic enzyme genes

Sterol regulatory element-binding protein-1 as a key transcription factor for nutritional induction of lipogenic enzyme genes

http://www.wikidata.org/entity/Q28646399

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Hepatic PCSK9 expression is regulated by nutritional status via insulin and sterol regulatory element-binding protein 1c The sterol-sensing endoplasmic reticulum (ER) membrane protein TRC8 hampers ER to Golgi transport of sterol regulatory element-binding protein-2 (SREBP-2)/SREBP cleavage-activated protein and reduces SREBP-2 cleavage Glucose activates ChREBP by increasing its rate of nuclear entry and relieving repression of its transcriptional activity Selective up-regulation of LXR-regulated genes ABCA1, ABCG1, and APOE in macrophages through increased endogenous synthesis of 24(S),25-epoxycholesterol Mechanisms of nutritional and hormonal regulation of lipogenesis Identification of liver X receptor-retinoid X receptor as an activator of the sterol regulatory element-binding protein 1c gene promoter Regulation of mouse sterol regulatory element-binding protein-1c gene (SREBP-1c) by oxysterol receptors, LXRalpha and LXRbeta Occupancy and function of the -150 sterol regulatory element and -65 E-box in nutritional regulation of the fatty acid synthase gene in living animals Regulation of glucose metabolism from a liver-centric perspective Genetically modified mouse models for the study of nonalcoholic fatty liver disease Dual functions of Insig proteins in cholesterol homeostasis Fat Metabolism Regulates Satiety Behavior in C. elegans.Transcriptional regulation of the murine acetyl-CoA synthetase 1 gene through multiple clustered binding sites for sterol regulatory element-binding proteins and a single neighboring site for Sp1 Regulation of lipogenesis by cyclin-dependent kinase 8-mediated control of SREBP-1 Direct interaction between USF and SREBP-1c mediates synergistic activation of the fatty-acid synthase promoter A role for smooth endoplasmic reticulum membrane cholesterol ester in determining the intracellular location and regulation of sterol-regulatory-element-binding protein-2 Statin-induced inhibition of the Rho-signaling pathway activates PPARalpha and induces HDL apoA-I Distinct roles of insulin and liver X receptor in the induction and cleavage of sterol regulatory element-binding protein-1c Liver X receptors as insulin-mediating factors in fatty acid and cholesterol biosynthesis PKClambda in liver mediates insulin-induced SREBP-1c expression and determines both hepatic lipid content and overall insulin sensitivity Acetyl-coenzyme A synthetase is a lipogenic enzyme controlled by SREBP-1 and energy status PIASy-mediated sumoylation of SREBP1c regulates hepatic lipid metabolism upon fasting signaling Effect of deficiency in SREBP cleavage-activating protein on lipid metabolism during intermittent hypoxia Salt-inducible kinase regulates hepatic lipogenesis by controlling SREBP-1c phosphorylation Maintaining cholesterol homeostasis: sterol regulatory element-binding proteins C elegans: a model for exploring the genetics of fat storage SREBPs: activators of the complete program of cholesterol and fatty acid synthesis in the liver Activation of a metabolic gene regulatory network downstream of mTOR complex 1 Glutathione deficiency down-regulates hepatic lipogenesis in rats.Lupin protein influences the expression of hepatic genes involved in fatty acid synthesis and triacylglycerol hydrolysis of adult rats.Glucose regulation of the acetyl-CoA carboxylase promoter PI in rat hepatocytes.Polyunsaturated fatty acids suppress hepatic sterol regulatory element-binding protein-1 expression by accelerating transcript decay.Nutrient-gene interactions: a single nutrient and hundreds of target genes.High mobility group protein-B1 interacts with sterol regulatory element-binding proteins to enhance their DNA binding.Transcriptome profiling of the feeding-to-fasting transition in chicken liver.Tissue cholesterol content alterations in streptozotocin-induced diabetic rats.Short term feeding of a high fat diet exerts an additive effect on hepatocellular damage and steatosis in liver-specific PTEN knockout mice Metabolic syndrome without obesity: Hepatic overexpression of 11beta-hydroxysteroid dehydrogenase type 1 in transgenic mice The role of hepatic fat accumulation in pathogenesis of non-alcoholic fatty liver disease (NAFLD).Genetic control of de novo lipogenesis: role in diet-induced obesity

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Sterol regulatory element-binding protein-1 as a key transcription factor for nutritional induction of lipogenic enzyme genes

http://www.wikidata.org/entity/Q28646399

description

1999 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

1999 թվականի դեկտեմբերին հրատարակված գիտական հոդված

@hy

article publié dans la revue scientifique Journal of Biological Chemistry

@fr

artículu científicu espublizáu en 1999

@ast

im Dezember 1999 veröffentlichter wissenschaftlicher Artikel

@de

scientific journal article

@en

vedecký článok (publikovaný 1999/12/10)

@sk

vědecký článek publikovaný v roce 1999

@cs

wetenschappelijk artikel (gepubliceerd op 1999/12/10)

@nl

наукова стаття, опублікована в грудні 1999

@uk

name

Sterol regulatory element-bind ...... tion of lipogenic enzyme genes

@ast

Sterol regulatory element-bind ...... tion of lipogenic enzyme genes

@en

Sterol regulatory element-bind ...... tion of lipogenic enzyme genes

@nl

type

label

Sterol regulatory element-bind ...... tion of lipogenic enzyme genes

@ast

Sterol regulatory element-bind ...... tion of lipogenic enzyme genes

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Sterol regulatory element-bind ...... tion of lipogenic enzyme genes

@nl

prefLabel

Sterol regulatory element-bind ...... tion of lipogenic enzyme genes

@ast

Sterol regulatory element-bind ...... tion of lipogenic enzyme genes

@en

Sterol regulatory element-bind ...... tion of lipogenic enzyme genes

@nl

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JBC.274.50.35832

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Journal of Biological Chemistry

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Sterol regulatory element-bind ...... tion of lipogenic enzyme genes

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F Shionoiri

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H Shimano

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J Osuga

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K Harada

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K Ohashi

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M Amemiya-Kudo

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N Yamada

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S Ishibashi

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T Gotoda

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Y Iizuka

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P2860

SREBP-2, a second basic-helix-loop-helix-leucine zipper protein that stimulates transcription by binding to a sterol regulatory element

Differential expression of exons 1a and 1c in mRNAs for sterol regulatory element binding protein-1 in human and mouse organs and cultured cells

Co-crystal structure of sterol regulatory element binding protein 1a at 2.3 A resolution

The SREBP pathway: regulation of cholesterol metabolism by proteolysis of a membrane-bound transcription factor

SREBP-1, a basic-helix-loop-helix-leucine zipper protein that controls transcription of the low density lipoprotein receptor gene

Molecular cloning and functional analysis of the promoter of the human squalene synthase gene

Elevated levels of SREBP-2 and cholesterol synthesis in livers of mice homozygous for a targeted disruption of the SREBP-1 gene

Essential role in vivo of upstream stimulatory factors for a normal dietary response of the fatty acid synthase gene in the liver

Differential stimulation of cholesterol and unsaturated fatty acid biosynthesis in cells expressing individual nuclear sterol regulatory element-binding proteins

Sterol regulatory element binding protein binds to a cis element in the promoter of the farnesyl diphosphate synthase gene.

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35832-35839

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50

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274

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Alyssa H. Hasty

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1999-12-01T00:00:00Z

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