Binding of inositol phosphate to DNA-PK and stimulation of double-strand break repair
about
Cloning and characterisation of hAps1 and hAps2, human diadenosine polyphosphate-metabolising Nudix hydrolasesIdentification and characterization of a novel inositol hexakisphosphate kinaseThe synthesis of inositol hexakisphosphate. Characterization of human inositol 1,3,4,5,6-pentakisphosphate 2-kinaseInvolvement of human polynucleotide kinase in double-strand break repair by non-homologous end joiningSynapsis of DNA ends by DNA-dependent protein kinaseNonhomologous end joining and V(D)J recombination require an additional factorProcessing of DNA for nonhomologous end-joining by cell-free extractArtemis is a phosphorylation target of ATM and ATR and is involved in the G2/M DNA damage checkpoint responseRegulation of immune cell development through soluble inositol-1,3,4,5-tetrakisphosphateEffect of inositol hexakisphosphate kinase 2 on transforming growth factor beta-activated kinase 1 and NF-kappaB activationInositol hexakisphosphate kinase 2 sensitizes ovarian carcinoma cells to multiple cancer therapeuticsInhibition of double-strand break non-homologous end-joining by cisplatin adducts in human cell extractsEffect of ionic strength and oxidation on the P-loop conformation of the protein tyrosine phosphatase-like phytase, PhyAsrInositol 1,3,4,5,6-pentakisphosphate 2-kinase is a distant IPK member with a singular inositide binding site for axial 2-OH recognitionDefining an allosteric circuit in the cysteine protease domain of Clostridium difficile toxinsSubstrate Binding in Protein-tyrosine Phosphatase-like Inositol PolyphosphatasesMHO1, an evolutionarily conserved gene, is synthetic lethal with PLC1; Mho1p has a role in invasive growth.Activation of the DExD/H-box protein Dbp5 by the nuclear-pore protein Gle1 and its coactivator InsP6 is required for mRNA export.Broad Spectrum Anticancer Activity of Myo-Inositol and Inositol HexakisphosphateA human short open reading frame (sORF)-encoded polypeptide that stimulates DNA end joiningBack in the water: the return of the inositol phosphatesNudix hydrolases that degrade dinucleoside and diphosphoinositol polyphosphates also have 5-phosphoribosyl 1-pyrophosphate (PRPP) pyrophosphatase activity that generates the glycolytic activator ribose 1,5-bisphosphateAn essential role for an inositol polyphosphate multikinase, Ipk2, in mouse embryogenesis and second messenger productionNeural tube defects in mice with reduced levels of inositol 1,3,4-trisphosphate 5/6-kinaseThe wavy Mutation Maps to the Inositol 1,4,5-Trisphosphate 3-Kinase 2 (IP3K2) Gene of Drosophila and Interacts with IP3R to Affect Wing DevelopmentActivation of the DNA-dependent protein kinase stimulates nuclear export of the androgen receptor in vitro.Increased transcription in hydroxyurea-treated root meristem cells of Vicia faba.Allosteric regulation of protease activity by small molecules.Expression of inositol 1,3,4-trisphosphate 5/6-kinase (ITPK1) and its role in neural tube defects.Inositol pyrophosphates regulate cell death and telomere length through phosphoinositide 3-kinase-related protein kinasesDisruption of the mouse inositol 1,3,4,5,6-pentakisphosphate 2-kinase gene, associated lethality, and tissue distribution of 2-kinase expressionIn vitro non-homologous DNA end joining assays--the 20th anniversary.Visualization of inositol phosphate-dependent mobility of Ku: depletion of the DNA-PK cofactor InsP6 inhibits Ku mobility.The pathway for the production of inositol hexakisphosphate in human cells.Phosphoinositide 3-kinase inhibition in cancer treatment.RAD51 supports spontaneous non-homologous recombination in mammalian cells, but not the corresponding process induced by topoisomerase inhibitorsOverexpression of the inositol phosphatase SopB in human 293 cells stimulates cellular chloride influx and inhibits nuclear mRNA exportProtective effect of inositol hexaphosphate against UVB damage in HaCaT cells and skin carcinogenesis in SKH1 hairless mice.Inositol and higher inositol phosphates in neural tissues: homeostasis, metabolism and functional significance.Gene deletion of inositol hexakisphosphate kinase 2 predisposes to aerodigestive tract carcinoma.
P2860
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P2860
Binding of inositol phosphate to DNA-PK and stimulation of double-strand break repair
description
2000 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2000
@ast
im September 2000 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2000/09/15)
@sk
vědecký článek publikovaný v roce 2000
@cs
wetenschappelijk artikel (gepubliceerd op 2000/09/15)
@nl
наукова стаття, опублікована у вересні 2000
@uk
مقالة علمية (نشرت في 15-9-2000)
@ar
name
Binding of inositol phosphate to DNA-PK and stimulation of double-strand break repair
@ast
Binding of inositol phosphate to DNA-PK and stimulation of double-strand break repair
@en
Binding of inositol phosphate to DNA-PK and stimulation of double-strand break repair
@nl
type
label
Binding of inositol phosphate to DNA-PK and stimulation of double-strand break repair
@ast
Binding of inositol phosphate to DNA-PK and stimulation of double-strand break repair
@en
Binding of inositol phosphate to DNA-PK and stimulation of double-strand break repair
@nl
prefLabel
Binding of inositol phosphate to DNA-PK and stimulation of double-strand break repair
@ast
Binding of inositol phosphate to DNA-PK and stimulation of double-strand break repair
@en
Binding of inositol phosphate to DNA-PK and stimulation of double-strand break repair
@nl
P2093
P3181
P1433
P1476
Binding of inositol phosphate to DNA-PK and stimulation of double-strand break repair
@en
P2093
C. Chappell
L. A. Hanakahi
M. Bartlet-Jones
S. C. West
P304
P3181
P356
10.1016/S0092-8674(00)00061-1
P407
P577
2000-09-15T00:00:00Z