A molecular clasp in the human immunodeficiency virus (HIV) type 1 TM protein determines the anti-HIV activity of gp41 derivatives: implication for viral fusion
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The Coronavirus Spike Protein Is a Class I Virus Fusion Protein: Structural and Functional Characterization of the Fusion Core ComplexInhibition of human immunodeficiency virus type 1 infectivity by the gp41 core: role of a conserved hydrophobic cavity in membrane fusionStructural and functional analysis of interhelical interactions in the human immunodeficiency virus type 1 gp41 envelope glycoprotein by alanine-scanning mutagenesis.Design of an engineered N-terminal HIV-1 gp41 trimer with enhanced stability and potencyRole of a Putative gp41 Dimerization Domain in Human Immunodeficiency Virus Type 1 Membrane FusionAtomic structure of a thermostable subdomain of HIV-1 gp41Role of human immunodeficiency virus (HIV) type 1 envelope in the anti-HIV activity of the betulinic acid derivative IC9564Design of potent inhibitors of HIV-1 entry from the gp41 N-peptide regionSCH-C (SCH 351125), an orally bioavailable, small molecule antagonist of the chemokine receptor CCR5, is a potent inhibitor of HIV-1 infection in vitro and in vivoEvidence that a prominent cavity in the coiled coil of HIV type 1 gp41 is an attractive drug targetDeterminants of human immunodeficiency virus type 1 resistance to gp41-derived inhibitory peptides.Maraviroc: the evidence for its potential in the management of HIVEvidence that the transition of HIV-1 gp41 into a six-helix bundle, not the bundle configuration, induces membrane fusionThe ectodomain of HIV-1 env subunit gp41 forms a soluble, alpha-helical, rod-like oligomer in the absence of gp120 and the N-terminal fusion peptideEmergence of resistant human immunodeficiency virus type 1 in patients receiving fusion inhibitor (T-20) monotherapy.Development of an HIV-1 Microbicide Based on Caulobacter crescentus: Blocking Infection by High-Density Display of Virus Entry Inhibitors.Closing the door to human immunodeficiency virus.Dilation of the human immunodeficiency virus-1 envelope glycoprotein fusion pore revealed by the inhibitory action of a synthetic peptide from gp41N-substituted pyrrole derivatives as novel human immunodeficiency virus type 1 entry inhibitors that interfere with the gp41 six-helix bundle formation and block virus fusion.Cyanovirin-N binds to gp120 to interfere with CD4-dependent human immunodeficiency virus type 1 virion binding, fusion, and infectivity but does not affect the CD4 binding site on gp120 or soluble CD4-induced conformational changes in gp120.Subdomain folding and biological activity of the core structure from human immunodeficiency virus type 1 gp41: implications for viral membrane fusion.Amino acid 36 in the human immunodeficiency virus type 1 gp41 ectodomain controls fusogenic activity: implications for the molecular mechanism of viral escape from a fusion inhibitorMutations in both gp120 and gp41 are responsible for the broad neutralization resistance of variant human immunodeficiency virus type 1 MN to antibodies directed at V3 and non-V3 epitopes.Mutations in the leucine zipper-like heptad repeat sequence of human immunodeficiency virus type 1 gp41 dominantly interfere with wild-type virus infectivity.Modifications that stabilize human immunodeficiency virus envelope glycoprotein trimers in solution.An antibody directed against the fusion peptide of Junin virus envelope glycoprotein GPC inhibits pH-induced membrane fusion.The role of the third beta strand in gp120 conformation and neutralization sensitivity of the HIV-1 primary isolate DH012Impact of human immunodeficiency virus type 1 gp41 amino acid substitutions selected during enfuvirtide treatment on gp41 binding and antiviral potency of enfuvirtide in vitro.Resistance to N-peptide fusion inhibitors correlates with thermodynamic stability of the gp41 six-helix bundle but not HIV entry kinetics.Genetic evidence that interhelical packing interactions in the gp41 core are critical for transition of the human immunodeficiency virus type 1 envelope glycoprotein to the fusion-active state.Inhibitory activity of synthetic peptide antibiotics on feline immunodeficiency virus infectivity in vitro.HIV entry inhibitors and their potential in HIV therapyHIV-1 envelope proteins complete their folding into six-helix bundles immediately after fusion pore formationInhibition of human immunodeficiency virus type 1 entry by a binding domain of Porphyromonas gingivalis gingipainRole of the envelope genetic context in the development of enfuvirtide resistance in human immunodeficiency virus type 1-infected patientsStructure and immune recognition of trimeric pre-fusion HIV-1 Env.The role of dynamin in HIV type 1 Env-mediated cell-cell fusion.Selection with a peptide fusion inhibitor corresponding to the first heptad repeat of HIV-1 gp41 identifies two genetic pathways conferring cross-resistance to peptide fusion inhibitors corresponding to the first and second heptad repeats (HR1 and HBiophysical characterization of recombinant proteins expressing the leucine zipper-like domain of the human immunodeficiency virus type 1 transmembrane protein gp41Human immunodeficiency virus type 1 envelope glycoprotein oligomerization requires the gp41 amphipathic alpha-helical/leucine zipper-like sequence
P2860
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P2860
A molecular clasp in the human immunodeficiency virus (HIV) type 1 TM protein determines the anti-HIV activity of gp41 derivatives: implication for viral fusion
description
1995 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
1995 թվականի հունիսին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 1995
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im Juni 1995 veröffentlichter wissenschaftlicher Artikel
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scientific journal article
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vedecký článok (publikovaný 1995/06/01)
@sk
vědecký článek publikovaný v roce 1995
@cs
wetenschappelijk artikel (gepubliceerd op 1995/06/01)
@nl
наукова стаття, опублікована в червні 1995
@uk
مقالة علمية (نشرت في يونيو 1995)
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name
A molecular clasp in the human ...... : implication for viral fusion
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A molecular clasp in the human ...... : implication for viral fusion
@en
A molecular clasp in the human ...... : implication for viral fusion
@nl
type
label
A molecular clasp in the human ...... : implication for viral fusion
@ast
A molecular clasp in the human ...... : implication for viral fusion
@en
A molecular clasp in the human ...... : implication for viral fusion
@nl
prefLabel
A molecular clasp in the human ...... : implication for viral fusion
@ast
A molecular clasp in the human ...... : implication for viral fusion
@en
A molecular clasp in the human ...... : implication for viral fusion
@nl
P2093
P2860
P1433
P1476
A molecular clasp in the human ...... : implication for viral fusion
@en
P2093
C. B. McDanal
C. H. Chen
D. P. Bolognesi
M. L. Greenberg
T. J. Matthews
P2860
P304
P577
1995-06-01T00:00:00Z