The integrin alpha(9)beta(1) binds to a novel recognition sequence (SVVYGLR) in the thrombin-cleaved amino-terminal fragment of osteopontin
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The lymphangiogenic vascular endothelial growth factors VEGF-C and -D are ligands for the integrin alpha9beta1Osteopontin as a means to cope with environmental insults: regulation of inflammation, tissue remodeling, and cell survivalSpermidine/spermine N1-acetyltransferase specifically binds to the integrin alpha9 subunit cytoplasmic domain and enhances cell migrationRole of Osteopontin in Liver DiseasesMolecular Basis of Recognition of Human Osteopontin by 23C3, a Potential Therapeutic Antibody for Treatment of Rheumatoid ArthritisFertilin beta and other ADAMs as integrin ligands: insights into cell adhesion and fertilizationRole of osteopontin in regulating hepatic inflammatory responses and toxic liver injuryOsteopontin expression by CD103- dendritic cells drives intestinal inflammationOsteopontin undergoes polymerization in vivo and gains chemotactic activity for neutrophils mediated by integrin alpha9beta1.Localization and expression of prothrombin in rodent osteoclasts and long bonesThe isolation and characterization of glycosylated phosphoproteins from herring fish bonesIdentification of the peptide sequences within the EIIIA (EDA) segment of fibronectin that mediate integrin alpha9beta1-dependent cellular activities.Polymeric osteopontin employs integrin alpha9beta1 as a receptor and attracts neutrophils by presenting a de novo binding siteIntegrin α9β1 in airway smooth muscle suppresses exaggerated airway narrowing.Inhibition of breast cancer cell adhesion and bone metastasis by the extracellular adherence protein of Staphylococcus aureusThrombin hydrolysis of human osteopontin is dependent on thrombin anion-binding exosites.Controlled spatial and conformational display of immobilised bone morphogenetic protein-2 and osteopontin signalling motifs regulates osteoblast adhesion and differentiation in vitro.Osteopontin is cleaved at multiple sites close to its integrin-binding motifs in milk and is a novel substrate for plasmin and cathepsin D.Osteopontin, inflammation and myogenesis: influencing regeneration, fibrosis and size of skeletal muscleRGD-independent binding of integrin alpha9beta1 to the ADAM-12 and -15 disintegrin domains mediates cell-cell interaction.Fatal bilateral chylothorax in mice lacking the integrin alpha9beta1.Elevation of osteopontin levels in brain tumor cells reduces burden and promotes survival through the inhibition of cell dispersalSecreted osteopontin is highly polymerized in human airways and fragmented in asthmatic airway secretionsProtein targets of inflammatory serine proteases and cardiovascular disease.Osteopontin: a key cytokine in cell-mediated and granulomatous inflammation.Geometrical microfeature cues for directing tubulogenesis of endothelial cellsOsteopontin level in synovial fluid is associated with the severity of joint pain and cartilage degradation after anterior cruciate ligament rupture.Duplication and diversification of the spermidine/spermine N1-acetyltransferase 1 genes in zebrafishA novel cryptic binding motif, LRSKSRSFQVSDEQY, in the C-terminal fragment of MMP-3/7-cleaved osteopontin as a novel ligand for α9β1 integrin is involved in the anti-type II collagen antibody-induced arthritis.Pre- and post-translational regulation of osteopontin in cancer.Thrombin-activatable carboxypeptidase B cleavage of osteopontin regulates neutrophil survival and synoviocyte binding in rheumatoid arthritisShort form of α9 promotes α9β1 integrin-dependent cell adhesion by modulating the function of the full-length α9 subunit.Essential role of the cryptic epitope SLAYGLR within osteopontin in a murine model of rheumatoid arthritisRole of the integrin-binding protein osteopontin in lymphatic metastasis of breast cancer.Association of p75(NTR) and α9β1 integrin modulates NGF-dependent cellular responses.Integrin alpha9 (ITGA9) expression and epigenetic silencing in human breast tumorsInhibition of Cellular Adhesion by Immunological Targeting of Osteopontin Neoepitopes Generated through Matrix Metalloproteinase and Thrombin CleavageOsteopontin regulates proliferation, apoptosis, and migration of murine claudin-low mammary tumor cells.Polydom/SVEP1 is a ligand for integrin α9β1.Osteopontin (OPN/SPP1) isoforms collectively enhance tumor cell invasion and dissemination in esophageal adenocarcinoma.
P2860
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P2860
The integrin alpha(9)beta(1) binds to a novel recognition sequence (SVVYGLR) in the thrombin-cleaved amino-terminal fragment of osteopontin
description
1999 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Journal of Biological Chemistry
@fr
artículu científicu espublizáu en 1999
@ast
im Dezember 1999 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 1999/12/17)
@sk
vědecký článek publikovaný v roce 1999
@cs
wetenschappelijk artikel (gepubliceerd op 1999/12/17)
@nl
наукова стаття, опублікована в грудні 1999
@uk
name
The integrin alpha(9)beta(1) b ...... rminal fragment of osteopontin
@ast
The integrin alpha(9)beta(1) b ...... rminal fragment of osteopontin
@en
The integrin alpha(9)beta(1) b ...... rminal fragment of osteopontin
@nl
type
label
The integrin alpha(9)beta(1) b ...... rminal fragment of osteopontin
@ast
The integrin alpha(9)beta(1) b ...... rminal fragment of osteopontin
@en
The integrin alpha(9)beta(1) b ...... rminal fragment of osteopontin
@nl
prefLabel
The integrin alpha(9)beta(1) b ...... rminal fragment of osteopontin
@ast
The integrin alpha(9)beta(1) b ...... rminal fragment of osteopontin
@en
The integrin alpha(9)beta(1) b ...... rminal fragment of osteopontin
@nl
P2093
P3181
P356
P1476
The integrin alpha(9)beta(1) b ...... rminal fragment of osteopontin
@en
P2093
D. Sheppard
H. Schneider
I. Murakami
M. Yamakido
N. Matsuura
S. Higashiyama
Y. Yokosaki
P304
36328–36334
P3181
P356
10.1074/JBC.274.51.36328
P407
P577
1999-12-17T00:00:00Z