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NLRP10 enhances Shigella-induced pro-inflammatory responsesRole of ADAM-9 disintegrin-cysteine-rich domains in human keratinocyte migrationEradication of melanomas by targeted elimination of a minor subset of tumor cellsA role for the human nucleotide-binding domain, leucine-rich repeat-containing family member NLRC5 in antiviral responsesA Disintegrin and Metalloprotease (ADAM): Historical Overview of Their FunctionsPlatelet integrin α6β1 controls lung metastasis through direct binding to cancer cell-derived ADAM9.Gene expression profiling reveals cross-talk between melanoma and fibroblasts: implications for host-tumor interactions in metastasis.Role of the snake venom toxin jararhagin in proinflammatory pathogenesis: in vitro and in vivo gene expression analysis of the effects of the toxin.The invasive potential of human melanoma cell lines correlates with their ability to alter fibroblast gene expression in vitro and the stromal microenvironment in vivo.Proteomic anatomy of human skin.Host response to human breast Invasive Ductal Carcinoma (IDC) as observed by changes in the stromal proteome.Structural decoding of netrin-4 reveals a regulatory function towards mature basement membranesFibroblast-matrix interactions in wound healing and fibrosis.Matrix metalloproteinase 14 is required for fibrous tissue expansionTumor-stroma interactions: their role in the control of tumor cell invasion.Human papillomavirus type 8 E6 oncoprotein inhibits transcription of the PDZ protein syntenin-2.Lack of integrin β5 in Merkel cell carcinomas and derived cell lines is frequently associated with Merkel cell polyomavirus positivityCD30 on extracellular vesicles from malignant Hodgkin cells supports damaging of CD30 ligand-expressing bystander cells with Brentuximab-Vedotin, in vitro.Metalloproteinases in melanoma.Deletion of ADAM-9 in HGF/CDK4 mice impairs melanoma development and metastasis.Primary tumor versus metastasis: new experimental models for studies on cancer cell homing and metastasis in melanoma.Ubiquitin C-terminal hydrolase-L1 potentiates cancer chemosensitivity by stabilizing NOXA.Stromal fibroblast-specific expression of ADAM-9 modulates proliferation and apoptosis in melanoma cells in vitro and in vivo.Role of ADAM-15 in wound healing and melanoma development.The disintegrin-like and cysteine-rich domains of ADAM-9 mediate interactions between melanoma cells and fibroblasts.Transmembrane collagen XVII, an epithelial adhesion protein, is shed from the cell surface by ADAMs.The proteasome inhibitor bortezomib sensitizes melanoma cells toward adoptive CTL attack.Identification and discrimination of extracellularly active cathepsins B and L in high-invasive melanoma cells.Adam-9 expression and regulation in human skin melanoma and melanoma cell lines.Fibroblast-Derived MMP-14 Regulates Collagen Homeostasis in Adult Skin.Evidence for a K+ channel requirement in spreading of rat basophilic leukemia cells on fibronectin-coated surfaces.Epidermal NLRP10 contributes to contact hypersensitivity responses in mice.IAP antagonization promotes inflammatory destruction of vascular endothelium.Deletion of the epidermis derived laminin γ1 chain leads to defects in the regulation of late hair morphogenesis.The reprolysin jararhagin, a snake venom metalloproteinase, functions as a fibrillar collagen agonist involved in fibroblast cell adhesion and signaling.Invasion of melanoma cells into dermal connective tissue in vitro: evidence for an important role of cysteine proteases.Loss of epidermal MMP-14 expression interferes with angiogenesis but not with re-epithelialization.Contact of high-invasive, but not low-invasive, melanoma cells to native collagen I induces the release of mature cathepsin B.Delayed wound healing and epidermal hyperproliferation in mice lacking JunB in the skin.Cell-Populated Collagen Lattice Models.
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P50
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hulumtuese
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հետազոտող
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Paola Zigrino
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Paola Zigrino
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Paola Zigrino
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Paola Zigrino
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Paola Zigrino
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Paola Zigrino
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Paola Zigrino
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Paola Zigrino
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Paola Zigrino
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Paola Zigrino
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Paola Zigrino
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Paola Zigrino
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Paola Zigrino
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Paola Zigrino
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Paola Zigrino
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P214
P106
P21
P214
P31
P496
0000-0002-7470-0064
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