ELMO domains, evolutionary and functional characterization of a novel GTPase-activating protein (GAP) domain for Arf protein family GTPases
about
An alteration in ELMOD3, an Arl2 GTPase-activating protein, is associated with hearing impairment in humansCharacterization of recombinant ELMOD (cell engulfment and motility domain) proteins as GTPase-activating proteins (GAPs) for ARF family GTPases.Tracing the Archaeal Origins of Eukaryotic Membrane-Trafficking System Building Blocks.The ARL2 GTPase is required for mitochondrial morphology, motility, and maintenance of ATP levels.ELMOD2 is anchored to lipid droplets by palmitoylation and regulates adipocyte triglyceride lipase recruitment.Proteomic analysis of murine testes lipid droplets.The abundance of the ARL2 GTPase and its GAP, ELMOD2, at mitochondria are modulated by the fusogenic activity of mitofusins and stressors.Ancient complexity, opisthokont plasticity, and discovery of the 11th subfamily of Arf GAP proteins.Loss-of-Function Mutations in ELMO2 Cause Intraosseous Vascular Malformation by Impeding RAC1 SignalingHigher order signaling: ARL2 as regulator of both mitochondrial fusion and microtubule dynamics allows integration of 2 essential cell functions.Arl13b regulates Shh signaling from both inside and outside the cilium.Knockdown of ELMO3 Suppresses Growth, Invasion and Metastasis of Colorectal Cancer.ELMO proteins transduce G protein-coupled receptor signal to control reorganization of actin cytoskeleton in chemotaxis of eukaryotic cells.Unexpected ancient paralogs and an evolutionary model for the COPII coat complex.ARF6 mediates nephrin tyrosine phosphorylation-induced podocyte cellular dynamicsSorting of lipidated cargo by the Arl2/Arl3 systemA barley Engulfment and Motility domain containing protein modulates Rho GTPase activating protein HvMAGAP1 function in the barley powdery mildew interaction.ELMOD1 stimulates ARF6-GTP hydrolysis to stabilize apical structures in developing vestibular hair cells.The ARL2 GTPase regulates mitochondrial fusion from the intermembrane space.GTPase-activating protein Elmod2 is essential for meiotic progression in mouse oocytes.Silencing ELMO3 Inhibits the Growth, Invasion, and Metastasis of Gastric Cancer
P2860
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P2860
ELMO domains, evolutionary and functional characterization of a novel GTPase-activating protein (GAP) domain for Arf protein family GTPases
description
2012 nî lūn-bûn
@nan
2012 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
ELMO domains, evolutionary and ...... for Arf protein family GTPases
@ast
ELMO domains, evolutionary and ...... for Arf protein family GTPases
@en
ELMO domains, evolutionary and ...... for Arf protein family GTPases
@nl
type
label
ELMO domains, evolutionary and ...... for Arf protein family GTPases
@ast
ELMO domains, evolutionary and ...... for Arf protein family GTPases
@en
ELMO domains, evolutionary and ...... for Arf protein family GTPases
@nl
prefLabel
ELMO domains, evolutionary and ...... for Arf protein family GTPases
@ast
ELMO domains, evolutionary and ...... for Arf protein family GTPases
@en
ELMO domains, evolutionary and ...... for Arf protein family GTPases
@nl
P2093
P2860
P356
P1476
ELMO domains, evolutionary and ...... for Arf protein family GTPases
@en
P2093
J Bradford Bowzard
Michael P East
Richard A Kahn
P2860
P304
39538-39553
P356
10.1074/JBC.M112.417477
P407
P577
2012-09-26T00:00:00Z