Superior antitumoral activity of dimerized targeted single-chain TRAIL fusion proteins under retention of tumor selectivity
about
Onto better TRAILs for cancer treatmentA novel capsid-modified oncolytic recombinant adenovirus type 5 for tumor-targeting gene therapy by intravenous routeAntitumor Activity of a Mesenchymal Stem Cell Line Stably Secreting a Tumor-Targeted TNF-Related Apoptosis-Inducing Ligand Fusion Protein.EGFR-targeted TRAIL and a Smac mimetic synergize to overcome apoptosis resistance in KRAS mutant colorectal cancer cells.Fn14•TRAIL effectively inhibits hepatocellular carcinoma growth.Construction of a linker library with widely controllable flexibility for fusion protein design.An optimized antibody-single-chain TRAIL fusion protein for cancer therapy.Engineered adenovirus fiber shaft fusion homotrimer of soluble TRAIL with enhanced stability and antitumor activity.Targeting cell death signaling in colorectal cancer: current strategies and future perspectives.Targeting of the tumor necrosis factor receptor superfamily for cancer immunotherapy.Genetic delivery of an immunoRNase by an oncolytic adenovirus enhances anticancer activity.Advancing targeted co-stimulation with antibody-fusion proteins by introducing TNF superfamily members in a single-chain format.The plant alkaloid and anti-leukemia drug homoharringtonine sensitizes resistant human colorectal carcinoma cells to TRAIL-induced apoptosis via multiple mechanisms.Death Receptors: New Opportunities in Cancer Therapy.Structural principles of tumor necrosis factor superfamily signaling.Pro-apoptotic effect of TRAIL-transfected endothelial progenitor cells on glioma cells.IgG-single-chain TRAIL fusion proteins for tumour therapy.Targeting scFv-Fc-scTRAIL fusion proteins to tumor cells.Bcl-2-mediated control of TRAIL-induced apoptotic response in the non-small lung cancer cell line NCI-H460 is effective at late caspase processing steps.
P2860
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P2860
Superior antitumoral activity of dimerized targeted single-chain TRAIL fusion proteins under retention of tumor selectivity
description
2012 nî lūn-bûn
@nan
2012 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Superior antitumoral activity ...... retention of tumor selectivity
@ast
Superior antitumoral activity ...... retention of tumor selectivity
@en
Superior antitumoral activity ...... retention of tumor selectivity
@nl
type
label
Superior antitumoral activity ...... retention of tumor selectivity
@ast
Superior antitumoral activity ...... retention of tumor selectivity
@en
Superior antitumoral activity ...... retention of tumor selectivity
@nl
prefLabel
Superior antitumoral activity ...... retention of tumor selectivity
@ast
Superior antitumoral activity ...... retention of tumor selectivity
@en
Superior antitumoral activity ...... retention of tumor selectivity
@nl
P2093
P2860
P3181
P356
P1476
Superior antitumoral activity ...... retention of tumor selectivity
@en
P2093
A K Nussler
K Pfizenmaier
M Siegemund
P2860
P3181
P356
10.1038/CDDIS.2012.29
P407
P577
2012-04-12T00:00:00Z