A neutralizing RNA aptamer against EGFR causes selective apoptotic cell death
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Aptamers in TherapeuticsAptamers: A promising chemical antibody for cancer therapyGeneration of Aptamers with an Expanded Chemical RepertoireAptamer-Drug ConjugatesTargeting Insulin Receptor with a Novel Internalizing AptamerAptamer-mediated impairment of EGFR-integrin αvβ3 complex inhibits vasculogenic mimicry and growth of triple-negative breast cancers.Toxicity and efficacy evaluation of multiple targeted polymalic acid conjugates for triple-negative breast cancer treatment.Multifunctional aptamer-miRNA conjugates for targeted cancer therapy.Selection of Nucleic Acid Aptamers Targeting Tumor Cell-Surface Protein BiomarkersDetection and characterization of cancer cells and pathogenic bacteria using aptamer-based nano-conjugatesPeptide-fluorescent bacteria complex as luminescent reagents for cancer diagnosis.Aptamer to ErbB-2/HER2 enhances degradation of the target and inhibits tumorigenic growth.Tetraspanins as regulators of the tumour microenvironment: implications for metastasis and therapeutic strategies.DNA aptamers that target human glioblastoma multiforme cells overexpressing epidermal growth factor receptor variant III in vitro.Selective Targeting to Glioma with Nucleic Acid AptamersAptamer targeting EGFRvIII mutant hampers its constitutive autophosphorylation and affects migration, invasion and proliferation of glioblastoma cells.Identification of sequence-structure RNA binding motifs for SELEX-derived aptamers.Current progress of RNA aptamer-based therapeutics.Targeting Axl with an high-affinity inhibitory aptamer.Systemic Delivery of Anti-miRNA for Suppression of Triple Negative Breast Cancer Utilizing RNA Nanotechnology.Smooth Muscle Cell-targeted RNA Aptamer Inhibits Neointimal Formation.Aptamer-miRNA-212 Conjugate Sensitizes NSCLC Cells to TRAIL.Stable RNA nanoparticles as potential new generation drugs for cancer therapy.Inhibition of receptor signaling and of glioblastoma-derived tumor growth by a novel PDGFRβ aptamer.Aptamers and their potential to selectively target aspects of EGF, Wnt/β-catenin and TGFβ-smad family signaling.Application of aptamers for targeted therapeutics.Oncogenic protein interfaces: small molecules, big challenges.Oligonucleotide aptamers: new tools for targeted cancer therapy.Nucleic acid aptamers in cancer research, diagnosis and therapy.Trends in the Design and Development of Specific Aptamers Against Peptides and Proteins.The promotion of salinomycin delivery to hepatocellular carcinoma cells through EGFR and CD133 aptamers conjugation by PLGA nanoparticles.Advancement of the Emerging Field of RNA Nanotechnology.Controllable Self-Assembly of RNA Tetrahedrons with Precise Shape and Size for Cancer Targeting.Nucleic acids in human glioma treatment: innovative approaches and recent resultsEnhanced EGFR Targeting Activity of Plasmonic Nanostructures with Engineered GE11 Peptide.Aptamers and Glioblastoma: Their Potential Use for Imaging and Therapeutic Applications.Molecular Elucidation of Disease Biomarkers at the Interface of Chemistry and Biology.Epidermal growth factor receptor aptamer-conjugated polymer-lipid hybrid nanoparticles enhance salinomycin delivery to osteosarcoma and cancer stem cells.Favorable biodistribution, specific targeting and conditional endosomal escape of RNA nanoparticles in cancer therapy.Nanoparticle orientation to control RNA loading and ligand display on extracellular vesicles for cancer regression.
P2860
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P2860
A neutralizing RNA aptamer against EGFR causes selective apoptotic cell death
description
2011 nî lūn-bûn
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2011 թուականին հրատարակուած գիտական յօդուած
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2011 թվականին հրատարակված գիտական հոդված
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2011年の論文
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2011年論文
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2011年論文
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2011年論文
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2011年論文
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2011年論文
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2011年论文
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name
A neutralizing RNA aptamer against EGFR causes selective apoptotic cell death
@ast
A neutralizing RNA aptamer against EGFR causes selective apoptotic cell death
@en
A neutralizing RNA aptamer against EGFR causes selective apoptotic cell death
@nl
type
label
A neutralizing RNA aptamer against EGFR causes selective apoptotic cell death
@ast
A neutralizing RNA aptamer against EGFR causes selective apoptotic cell death
@en
A neutralizing RNA aptamer against EGFR causes selective apoptotic cell death
@nl
prefLabel
A neutralizing RNA aptamer against EGFR causes selective apoptotic cell death
@ast
A neutralizing RNA aptamer against EGFR causes selective apoptotic cell death
@en
A neutralizing RNA aptamer against EGFR causes selective apoptotic cell death
@nl
P2093
P2860
P50
P3181
P1433
P1476
A neutralizing RNA aptamer against EGFR causes selective apoptotic cell death
@en
P2093
Andrea Affuso
Immacolata Longobardo
Laura Cerchia
Vittorio de Franciscis
P2860
P304
P3181
P356
10.1371/JOURNAL.PONE.0024071
P407
P577
2011-01-01T00:00:00Z