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Disentangling molecular relationships with a causal inference test

Disentangling molecular relationships with a causal inference test

http://www.wikidata.org/entity/Q28742231

about

Pharmacological validation of candidate causal sleep genes identified in an N2 cross Autoimmune diseases - connecting risk alleles with molecular traits of the immune system.Genome-wide significant loci: how important are they? Systems genetics to understand heritability of coronary artery disease and other common complex disorders Genetic Regulation of Adipose Gene Expression and Cardio-Metabolic Traits.Epigenome-wide association of liver methylation patterns and complex metabolic traits in mice Gene bionetworks involved in the epigenetic transgenerational inheritance of altered mate preference: environmental epigenetics and evolutionary biology.Biomarkers for combat-related PTSD: focus on molecular networks from high-dimensional data.Integrative analysis of DNA methylation and gene expression data identifies EPAS1 as a key regulator of COPD.Epigenome-wide association data implicates DNA methylation-mediated genetic risk in psoriasis.Multi-omics approaches to disease.Gene expression network reconstruction by convex feature selection when incorporating genetic perturbations.Sox5 regulates beta-cell phenotype and is reduced in type 2 diabetes Systematic detection of polygenic cis-regulatory evolution.Cis and trans effects of human genomic variants on gene expression.Genome-wide associations between genetic and epigenetic variation influence mRNA expression and insulin secretion in human pancreatic islets.Decision tree-based method for integrating gene expression, demographic, and clinical data to determine disease endotypes.Meditation and vacation effects have an impact on disease-associated molecular phenotypes.Epigenome-wide association data implicate DNA methylation as an intermediary of genetic risk in rheumatoid arthritis.Evolving toward a human-cell based and multiscale approach to drug discovery for CNS disorders.Mediation analysis demonstrates that trans-eQTLs are often explained by cis-mediation: a genome-wide analysis among 1,800 South Asians Inference of gene regulatory networks with sparse structural equation models exploiting genetic perturbations.An integrated epigenomic analysis for type 2 diabetes susceptibility loci in monozygotic twins.Risk of childhood asthma is associated with CpG-site polymorphisms, regional DNA methylation and mRNA levels at the GSDMB/ORMDL3 locus Maternal body mass index in early pregnancy and offspring asthma, rhinitis and eczema up to 16 years of age The causal effect of red blood cell folate on genome-wide methylation in cord blood: a Mendelian randomization approach.Genome-wide association study identifies peanut allergy-specific loci and evidence of epigenetic mediation in US children Identification of causal genes, networks, and transcriptional regulators of REM sleep and wake.A Genome-Wide Association Study of a Biomarker of Nicotine Metabolism.cit: hypothesis testing software for mediation analysis in genomic applications.A Genome-Wide mQTL Analysis in Human Adipose Tissue Identifies Genetic Variants Associated with DNA Methylation, Gene Expression and Metabolic Traits.Limited Contribution of DNA Methylation Variation to Expression Regulation in Arabidopsis thaliana.Layered genetic control of DNA methylation and gene expression: a locus of multiple sclerosis in healthy individuals.Common Genetic Polymorphisms Influence Blood Biomarker Measurements in COPD.Identification of a Putative Quantitative Trait Gene for Resistance to Obesity in Mice Using Transcriptome Analysis and Causal Inference Tests.Modeling causality for pairs of phenotypes in system genetics A systems approach identifies networks and genes linking sleep and stress: implications for neuropsychiatric disorders.Passive and active DNA methylation and the interplay with genetic variation in gene regulation Tissue-Specific and Genetic Regulation of Insulin Sensitivity-Associated Transcripts in African Americans.Integrative genomic analysis of the human immune response to influenza vaccination.The epigenetic basis of common human disease.

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Disentangling molecular relationships with a causal inference test

http://www.wikidata.org/entity/Q28742231

description

2009 nî lūn-bûn

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2009 թուականի Մայիսին հրատարակուած գիտական յօդուած

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2009 թվականի մայիսին հրատարակված գիտական հոդված

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2009年の論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年论文

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name

Disentangling molecular relationships with a causal inference test

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Disentangling molecular relationships with a causal inference test

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Disentangling molecular relationships with a causal inference test

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type

label

Disentangling molecular relationships with a causal inference test

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Disentangling molecular relationships with a causal inference test

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Disentangling molecular relationships with a causal inference test

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prefLabel

Disentangling molecular relationships with a causal inference test

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Disentangling molecular relationships with a causal inference test

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Disentangling molecular relationships with a causal inference test

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Disentangling molecular relationships with a causal inference test

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Bin Zhang

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Eric E Schadt

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Joshua Millstein

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Jun Zhu

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P2860

'Mendelian randomization': can genetic epidemiology contribute to understanding environmental determinants of disease?

Variations in DNA elucidate molecular networks that cause disease

Harnessing naturally randomized transcription to infer regulatory relationships among genes

Mendelian randomization as an instrumental variable approach to causal inference

Genetics of gene expression and its effect on disease

An integrative genomics approach to infer causal associations between gene expression and disease

R/qtl: QTL mapping in experimental crosses

Genetics of gene expression surveyed in maize, mouse and man

A general framework for weighted gene co-expression network analysis

Causal inference of regulator-target pairs by gene mapping of expression phenotypes.

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