Targeting vascular NADPH oxidase 1 blocks tumor angiogenesis through a PPARα mediated mechanism
about
NADPH oxidase inhibitors: a decade of discovery from Nox2ds to HTSTargeting NADPH oxidases for the treatment of cancer and inflammationEvolution of NADPH Oxidase Inhibitors: Selectivity and Mechanisms for Target EngagementBiochemistry, physiology, and pathophysiology of NADPH oxidases in the cardiovascular systemRedox balance dynamically regulates vascular growth and remodelingOxidative stress in cancer and fibrosis: Opportunity for therapeutic intervention with antioxidant compounds, enzymes, and nanoparticlesThe Role of PTEN in Tumor AngiogenesisReactive oxygen species in inflammation and tissue injuryRegulation of NADPH-dependent Nitric Oxide and reactive oxygen species signalling in endothelial and melanoma cells by a photoactive NADPH analogue.Copper Transport Protein Antioxidant-1 Promotes Inflammatory Neovascularization via Chaperone and Transcription Factor Function.NADPH oxidases in vascular pathology.The quest for selective nox inhibitors and therapeutics: challenges, triumphs and pitfallsNADPH oxidase, NOX1, mediates vascular injury in ischemic retinopathy.NADPH oxidase 1 supports proliferation of colon cancer cells by modulating reactive oxygen species-dependent signal transduction.NADPH Oxidases: Insights into Selected Functions and Mechanisms of Action in Cancer and Stem Cells.Roles of Nicotinamide Adenine Dinucleotide Phosphate (NADPH) Oxidase in Angiogenesis: Isoform-Specific EffectsOxidative stress and hepatic Nox proteins in chronic hepatitis C and hepatocellular carcinoma.Evolution of the ferric reductase domain (FRD) superfamily: modularity, functional diversification, and signature motifsUpdates of reactive oxygen species in melanoma etiology and progression.Inhibition of NOX1/4 with GKT137831: a potential novel treatment to attenuate neuroglial cell inflammation in the retina.NADPH oxidase 4 is expressed in pulmonary artery adventitia and contributes to hypertensive vascular remodelingSucrose non-fermenting related kinase enzyme is essential for cardiac metabolismRegulation of NADPH oxidase 5 by protein kinase C isoforms.Rap1 promotes VEGFR2 activation and angiogenesis by a mechanism involving integrin αvβ₃.Relationship between expression of NADPH oxidase 2 and invasion and prognosis of human gastric cancerDeficiency of NOX1 or NOX4 Prevents Liver Inflammation and Fibrosis in Mice through Inhibition of Hepatic Stellate Cell Activation.Redox signaling at invasive microdomains in cancer cells.Nox Inhibitors & Therapies: Rational Design of Peptidic and Small Molecule InhibitorsTransforming growth factor-β1 requires NADPH oxidase 4 for angiogenesis in vitro and in vivoRegulation of NAD(P)H oxidases by AMPK in cardiovascular systemsThe NOX toolbox: validating the role of NADPH oxidases in physiology and disease.Nuclear receptors as modulators of the tumor microenvironment.The role of Nox-mediated oxidation in the regulation of cytoskeletal dynamicsSuppressive effects of the NADPH oxidase inhibitor apocynin on intestinal tumorigenesis in obese KK-A(y) and Apc mutant Min mice.Therapeutic effects of PPARα agonists on diabetic retinopathy in type 1 diabetes modelsNADPH oxidase biology and the regulation of tyrosine kinase receptor signaling and cancer drug cytotoxicityCharacterization of NADPH oxidase 5 expression in human tumors and tumor cell lines with a novel mouse monoclonal antibody.Selective recapitulation of conserved and nonconserved regions of putative NOXA1 protein activation domain confers isoform-specific inhibition of Nox1 oxidase and attenuation of endothelial cell migration.Oxidative stress in angiogenesis and vascular diseaseHemorrhagic transformation after ischemic stroke in animals and humans
P2860
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P2860
Targeting vascular NADPH oxidase 1 blocks tumor angiogenesis through a PPARα mediated mechanism
description
2011 nî lūn-bûn
@nan
2011 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Targeting vascular NADPH oxida ...... ugh a PPARα mediated mechanism
@ast
Targeting vascular NADPH oxida ...... ugh a PPARα mediated mechanism
@en
Targeting vascular NADPH oxida ...... ugh a PPARα mediated mechanism
@nl
type
label
Targeting vascular NADPH oxida ...... ugh a PPARα mediated mechanism
@ast
Targeting vascular NADPH oxida ...... ugh a PPARα mediated mechanism
@en
Targeting vascular NADPH oxida ...... ugh a PPARα mediated mechanism
@nl
prefLabel
Targeting vascular NADPH oxida ...... ugh a PPARα mediated mechanism
@ast
Targeting vascular NADPH oxida ...... ugh a PPARα mediated mechanism
@en
Targeting vascular NADPH oxida ...... ugh a PPARα mediated mechanism
@nl
P2093
P2860
P50
P1433
P1476
Targeting vascular NADPH oxida ...... ugh a PPARα mediated mechanism
@en
P2093
Christine Deffert
Curzio Rüegg
Cédric Szyndralewiez
Freddy Heitz
Jack Arbiser
Karl Heinz Krause
Liliane Michalik
Olivier Basset
Patrick Page
Sarah Garrido-Urbani
P2860
P304
P356
10.1371/JOURNAL.PONE.0014665
P407
P577
2011-02-07T00:00:00Z