Altered expression of insulin receptor isoforms in breast cancer
about
Understanding the Key to Targeting the IGF Axis in Cancer: A Biomarker AssessmentA framework for the in vitro evaluation of cancer-relevant molecular characteristics and mitogenic potency of insulin analogues.Hyperinsulinemia promotes metastasis to the lung in a mouse model of Her2-mediated breast cancer.Reduced insulin-like growth factor I receptor and altered insulin receptor isoform mRNAs in normal mucosa predict colorectal adenoma risk.Insulin receptor (IR) and insulin-like growth factor receptor 1 (IGF-1R) signaling systems: novel treatment strategies for cancer.Increased IR-A/IR-B ratio in non-small cell lung cancers associates with lower epithelial-mesenchymal transition signature and longer survival in squamous cell lung carcinomaTranscriptome-wide landscape of pre-mRNA alternative splicing associated with metastatic colonizationHighly specific role of the insulin receptor in breast cancer progression.Phase I dose-escalation study of MEDI-573, a bispecific, antiligand monoclonal antibody against IGFI and IGFII, in patients with advanced solid tumorsQuantifying insulin receptor isoform expression in FFPE breast tumorsObesity and intestinal epithelial deletion of the insulin receptor, but not the IGF 1 receptor, affect radiation-induced apoptosis in colon.IGF1R inhibition in mammary epithelia promotes canonical Wnt signaling and Wnt1-driven tumorsA twenty-first century cancer epidemic caused by obesity: the involvement of insulin, diabetes, and insulin-like growth factorsInsulin receptor isoform switching in intestinal stem cells, progenitors, differentiated lineages and tumors: evidence that IR-B limits proliferation.Epidemiology and molecular mechanisms tying obesity, diabetes, and the metabolic syndrome with cancer.Pro-angiogenic Role of Insulin: From Physiology to Pathology.Insulin and IGFs in obesity-related breast cancer.Obesity, diabetes and cancer: insight into the relationship from a cohort with growth hormone receptor deficiency.Insulin receptor isoforms: an integrated view focused on gestational diabetes mellitus.Obesity and Cancer Mechanisms: Cancer Metabolism.Oncogenic functions of IGF1R and INSR in prostate cancer include enhanced tumor growth, cell migration and angiogenesis.A dual-specific IGF-I/II human engineered antibody domain inhibits IGF signaling in breast cancer cells.
P2860
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P2860
Altered expression of insulin receptor isoforms in breast cancer
description
2011 nî lūn-bûn
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2011 թուականին հրատարակուած գիտական յօդուած
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2011 թվականին հրատարակված գիտական հոդված
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2011年の論文
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2011年論文
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2011年論文
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2011年論文
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2011年論文
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2011年論文
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2011年论文
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name
Altered expression of insulin receptor isoforms in breast cancer
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Altered expression of insulin receptor isoforms in breast cancer
@en
Altered expression of insulin receptor isoforms in breast cancer
@nl
type
label
Altered expression of insulin receptor isoforms in breast cancer
@ast
Altered expression of insulin receptor isoforms in breast cancer
@en
Altered expression of insulin receptor isoforms in breast cancer
@nl
prefLabel
Altered expression of insulin receptor isoforms in breast cancer
@ast
Altered expression of insulin receptor isoforms in breast cancer
@en
Altered expression of insulin receptor isoforms in breast cancer
@nl
P2093
P2860
P1433
P1476
Altered expression of insulin receptor isoforms in breast cancer
@en
P2093
Anmarie Boutrin
Bahija Jallal
Chris Morehouse
Jaye Viner
Jiaqi Huang
Katie Streicher
Laura Richman
Meggan Czapiga
Philip Brohawn
P2860
P304
P356
10.1371/JOURNAL.PONE.0026177
P407
P577
2011-01-01T00:00:00Z