The Tritope Model for restrictive recognition of antigen by T-cells II. Implications for ontogeny, evolution and physiology
about
sameAs
Contemplating Bretscher's View that the Tritope Model is 'Implausible'Challenging the Tritope Model of T cell receptor structure-function relationships with classical data on 'super' and 'allo-MHC' antigens.On the opposing views of the self-nonself discrimination by the immune system.An in depth analysis of the concept of "polyspecificity" assumed to characterize TCR/BCR recognitionOn the logic of restrictive recognition of peptide by the T-cell antigen receptor.Why rethink the structure-function relationships regulating TCR behavior?What does the T-cell receptor recognize when it docks on an MHC-encoded restricting element?A hypothesis accounting for the paradoxical expression of the D gene segment in the BCR and the TCR.What roles do regulatory T cells play in the control of the adaptive immune response?Signaling interactions predicted by the Tritope model of the TCR.Thoughts on Positive Selection in Thymus.Is the Framework of Cohn's 'Tritope Model' for How T Cell Receptors Recognize Peptide/Self-MHC Complexes and Allo-MHC Plausible?The discussion with Jacques Miller: illustrating the limitations of pure empiricism.On recognizing 'shades-of-gray' (self-nonself discrimination) or 'colour' (Integrity model) by the immune system.
P2860
Q26743441-574CD2AD-B0A2-4DA2-9DFC-1E0903CE4AD7Q30652074-81EAD807-FBCD-4DE1-9AED-15D6CB5BF4B9Q33894534-DE93C96E-D09E-4B71-858B-BCDF7401A5C8Q33944138-51D955B9-8399-4B9C-8C99-7EB9D83E49E0Q34899954-BF551C4F-D763-4E6C-9473-BCF9AB252A57Q35939327-39487931-4A9F-4026-BC44-3C199D766331Q36766201-93BB2ACA-5821-437B-A544-5E4DB2D719D4Q37193981-3645CAE6-765B-42B2-AF70-AC2655274B2BQ37227956-C428BDAA-370D-42E7-B510-D3DD30A03139Q38647558-84E6A170-4E2A-4069-B096-9FE551962007Q38718998-B9B07DE0-305F-4181-97EB-6F8AB1CC1986Q38780187-BC8F00B6-F97D-4191-BA2A-04BE186F0A92Q42758267-A9EE9CCA-4AAA-49C7-96E8-0288676A49A1Q44312779-206562D2-963E-43B3-A110-5BD8ADB74AD8
P2860
The Tritope Model for restrictive recognition of antigen by T-cells II. Implications for ontogeny, evolution and physiology
description
2008 nî lūn-bûn
@nan
2008 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
The Tritope Model for restrict ...... geny, evolution and physiology
@ast
The Tritope Model for restrict ...... geny, evolution and physiology
@en
The Tritope Model for restrict ...... geny, evolution and physiology
@nl
type
label
The Tritope Model for restrict ...... geny, evolution and physiology
@ast
The Tritope Model for restrict ...... geny, evolution and physiology
@en
The Tritope Model for restrict ...... geny, evolution and physiology
@nl
prefLabel
The Tritope Model for restrict ...... geny, evolution and physiology
@ast
The Tritope Model for restrict ...... geny, evolution and physiology
@en
The Tritope Model for restrict ...... geny, evolution and physiology
@nl
P2860
P1433
P1476
The Tritope Model for restrict ...... geny, evolution and physiology
@en
P2093
Melvin Cohn
P2860
P304
P356
10.1016/J.MOLIMM.2006.02.033
P407
P577
2008-02-01T00:00:00Z