The human DNA repair factor XPC-HR23B distinguishes stereoisomeric benzo[a]pyrenyl-DNA lesions
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Xeroderma pigmentosum group C sensor: unprecedented recognition strategy and tight spatiotemporal regulationNucleotide excision repair in eukaryotesNuclear Magnetic Resonance Studies of an N 2 -Guanine Adduct Derived from the Tumorigen Dibenzo[ a , l ]pyrene in DNA: Impact of Adduct Stereochemistry, Size, and Local DNA Sequence on Solution ConformationsXPC: Going where no DNA damage sensor has gone beforeNucleotide excision repair efficiencies of bulky carcinogen-DNA adducts are governed by a balance between stabilizing and destabilizing interactionsDifferential nucleotide excision repair susceptibility of bulky DNA adducts in different sequence contexts: hierarchies of recognition signalsTwo-stage dynamic DNA quality check by xeroderma pigmentosum group C protein.Exploring damage recognition models in prokaryotic nucleotide excision repair with a benzo[a]pyrene-derived lesion in UvrBEntrapment of a Histone Tail by a DNA Lesion in a Nucleosome Suggests the Lesion Impacts Epigenetic Marking: A Molecular Dynamics Study.Sequential recruitment of the repair factors during NER: the role of XPG in initiating the resynthesis step.Repair of laser-localized DNA interstrand cross-links in G1 phase mammalian cellsOne-electron oxidation of a pyrenyl photosensitizer covalently attached to DNA and competition between its further oxidation and DNA hole injectionThe relationships between XPC binding to conformationally diverse DNA adducts and their excision by the human NER system: is there a correlation?Nucleotide Excision Repair Lesion-Recognition Protein Rad4 Captures a Pre-Flipped Partner Base in a Benzo[a]pyrene-Derived DNA Lesion: How Structure Impacts the Binding PathwayDNA-Destabilizing Agents as an Alternative Approach for Targeting DNA: Mechanisms of Action and Cellular ConsequencesFormation and repair of tobacco carcinogen-derived bulky DNA adductsInefficient nucleotide excision repair in human cell extracts of the N-(deoxyguanosin-8-yl)-6-aminochrysene and 5-(deoxyguanosin-N(2)-yl)-6-aminochrysene adducts derived from 6-nitrochrysene.Chiral toxicology: it's the same thing...only different.Adenine-DNA adduct derived from the nitroreduction of 6-nitrochrysene is more resistant to nucleotide excision repair than guanine-DNA adducts.Resistance of bulky DNA lesions to nucleotide excision repair can result from extensive aromatic lesion-base stacking interactions.Probing for DNA damage with β-hairpins: similarities in incision efficiencies of bulky DNA adducts by prokaryotic and human nucleotide excision repair systems in vitroResistance to Nucleotide Excision Repair of Bulky Guanine Adducts Opposite Abasic Sites in DNA Duplexes and Relationships between Structure and FunctionStructural, energetic and dynamic properties of guanine(C8)-thymine(N3) cross-links in DNA provide insights on susceptibility to nucleotide excision repair.Lack of recognition by global-genome nucleotide excision repair accounts for the high mutagenicity and persistence of aristolactam-DNA adducts.Base and Nucleotide Excision Repair of Oxidatively Generated Guanine Lesions in DNA.Expression and the Peculiar Enzymatic Behavior of the Trypanosoma cruzi NTH1 DNA GlycosylaseNucleotide excision repair of 2-acetylaminofluorene- and 2-aminofluorene-(C8)-guanine adducts: molecular dynamics simulations elucidate how lesion structure and base sequence context impact repair efficienciesThe efficiencies of damage recognition and excision correlate with duplex destabilization induced by acetylaminofluorene adducts in human nucleotide excision repair.DNA repair capacity in peripheral lymphocytes predicts survival of patients with non-small-cell lung cancer treated with first-line platinum-based chemotherapy.Adenine-DNA adducts derived from the highly tumorigenic Dibenzo[a,l]pyrene are resistant to nucleotide excision repair while guanine adducts are notNew synthetic substrates of mammalian nucleotide excision repair systemThe sequence dependence of human nucleotide excision repair efficiencies of benzo[a]pyrene-derived DNA lesions: insights into the structural factors that favor dual incisionsXeroderma pigmentosum complementation group C protein (XPC) serves as a general sensor of damaged DNA.C8-linked bulky guanosine DNA adducts: experimental and computational insights into adduct conformational preferences and resulting mutagenicity.Molecular mechanism of global genome nucleotide excision repair.Removal of oxidatively generated DNA damage by overlapping repair pathways.Repair-Resistant DNA Lesions.Mechanism of error-free replication across benzo[a]pyrene stereoisomers by Rev1 DNA polymerase.Dynamics of a benzo[a]pyrene-derived guanine DNA lesion in TGT and CGC sequence contexts: enhanced mobility in TGT explains conformational heterogeneity, flexible bending, and greater susceptibility to nucleotide excision repair.Human and yeast DNA damage recognition complexes bind with high affinity DNA structures mimicking in size transcription bubble.
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P2860
The human DNA repair factor XPC-HR23B distinguishes stereoisomeric benzo[a]pyrenyl-DNA lesions
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2007 nî lūn-bûn
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2007 թուականի Յունիսին հրատարակուած գիտական յօդուած
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2007 թվականի հունիսին հրատարակված գիտական հոդված
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2007年の論文
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2007年論文
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2007年論文
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2007年論文
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2007年論文
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2007年論文
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2007年论文
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The human DNA repair factor XP ...... ic benzo[a]pyrenyl-DNA lesions
@ast
The human DNA repair factor XP ...... ic benzo[a]pyrenyl-DNA lesions
@en
The human DNA repair factor XP ...... ic benzo[a]pyrenyl-DNA lesions
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label
The human DNA repair factor XP ...... ic benzo[a]pyrenyl-DNA lesions
@ast
The human DNA repair factor XP ...... ic benzo[a]pyrenyl-DNA lesions
@en
The human DNA repair factor XP ...... ic benzo[a]pyrenyl-DNA lesions
@nl
prefLabel
The human DNA repair factor XP ...... ic benzo[a]pyrenyl-DNA lesions
@ast
The human DNA repair factor XP ...... ic benzo[a]pyrenyl-DNA lesions
@en
The human DNA repair factor XP ...... ic benzo[a]pyrenyl-DNA lesions
@nl
P2093
P2860
P3181
P356
P1433
P1476
The human DNA repair factor XP ...... ic benzo[a]pyrenyl-DNA lesions
@en
P2093
Alexander Kolbanovskiy
Angels Tapias
Konstantin Kropachev
Marina Kolbanovskiy
Nicholas E Geacintov
Suse Broyde
P2860
P304
P3181
P356
10.1038/SJ.EMBOJ.7601730
P407
P577
2007-06-20T00:00:00Z