Metal ion catalysis during group II intron self-splicing: parallels with the spliceosome
about
Tertiary architecture of the Oceanobacillus iheyensis group II intronActivity of 3'-thioAMP derivatives as ribosomal P-site substrates.Functional identification of catalytic metal ion binding sites within RNA.Solution structure of domain 5 of a group II intron ribozyme reveals a new RNA motifX-ray Structures of U2 snRNA−Branchpoint Duplexes Containing Conserved Pseudouridines † ‡Coordination of divalent metal ions in the active site of poly(A)-specific ribonucleaseMitochondrial Mg(2+) homeostasis is critical for group II intron splicing in vivoA ribozyme selected from variants of U6 snRNA promotes 2',5'-branch formationRecent advances in the elucidation of the mechanisms of action of ribozymesRNA structure analysis of human spliceosomes reveals a compact 3D arrangement of snRNAs at the catalytic core.RNA-RNA interactions and pre-mRNA mislocalization as drivers of group II intron loss from nuclear genomes.A further investigation and reappraisal of the thio effect in the cleavage reaction catalyzed by a hammerhead ribozyme.Nuclear expression of a group II intron is consistent with spliceosomal intron ancestry.The use of divalent metal ions by type II topoisomerases.A tertiary interaction detected in a human U2-U6 snRNA complex assembled in vitro resembles a genetically proven interaction in yeast.The conserved central domain of yeast U6 snRNA: importance of U2-U6 helix Ia in spliceosome assembly.Characterization of the catalytic activity of U2 and U6 snRNAsNew tertiary constraints between the RNA components of active yeast spliceosomes: a photo-crosslinking study.RNA catalyses nuclear pre-mRNA splicingRNA-protein interactions that regulate pre-mRNA splicing.Evidence for a group II intron-like catalytic triplex in the spliceosomeA general and efficient approach for the construction of RNA oligonucleotides containing a 5'-phosphorothiolate linkage.Single-molecule analysis of protein-free U2-U6 snRNAs.Use of divalent metal ions in the DNA cleavage reaction of topoisomerase IV.The tertiary structure of group II introns: implications for biological function and evolutionStudying metal ion binding properties of a three-way junction RNA by heteronuclear NMR.Human topoisomerase IIalpha uses a two-metal-ion mechanism for DNA cleavage.Conformational heterogeneity of the protein-free human spliceosomal U2-U6 snRNA complexMetal switch-controlled myosin II from Dictyostelium discoideum supports closure of nucleotide pocket during ATP binding coupled to detachment from actin filamentsUse of divalent metal ions in the dna cleavage reaction of human type II topoisomerases.A glimpse into the active site of a group II intron and maybe the spliceosome, too.Metal ion interactions in the DNA cleavage/ligation active site of human topoisomerase IIalphaIdentification of catalytic metal ion ligands in ribozymes.Metal ion catalysis during the exon-ligation step of nuclear pre-mRNA splicing: extending the parallels between the spliceosome and group II intronsActive site constraints in the hydrolysis reaction catalyzed by bacterial RNase P: analysis of precursor tRNAs with a single 3'-S-phosphorothiolate internucleotide linkageSplicing of an intervening sequence by protein-free human snRNAs.Structural Insights into the Mechanism of Group II Intron Splicing.Visualizing the solvent-inaccessible core of a group II intron ribozymeSynthesis and biochemical application of 2'-O-methyl-3'-thioguanosine as a probe to explore group I intron catalysis.The linear form of a group II intron catalyzes efficient autocatalytic reverse splicing, establishing a potential for mobility.
P2860
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P2860
Metal ion catalysis during group II intron self-splicing: parallels with the spliceosome
description
1999 nî lūn-bûn
@nan
1999 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Metal ion catalysis during group II intron self-splicing: parallels with the spliceosome
@ast
Metal ion catalysis during group II intron self-splicing: parallels with the spliceosome
@en
type
label
Metal ion catalysis during group II intron self-splicing: parallels with the spliceosome
@ast
Metal ion catalysis during group II intron self-splicing: parallels with the spliceosome
@en
prefLabel
Metal ion catalysis during group II intron self-splicing: parallels with the spliceosome
@ast
Metal ion catalysis during group II intron self-splicing: parallels with the spliceosome
@en
P2093
P2860
P356
P1433
P1476
Metal ion catalysis during group II intron self-splicing: parallels with the spliceosome
@en
P2093
E J Sontheimer
J A Piccirilli
P M Gordon
P2860
P304
P356
10.1101/GAD.13.13.1729
P407
P577
1999-07-01T00:00:00Z