Metal ion catalysis during group II intron self-splicing: parallels with the spliceosome - Wikidata - wikimedia - TriplyDB

Metal ion catalysis during group II intron self-splicing: parallels with the spliceosome

Metal ion catalysis during group II intron self-splicing: parallels with the spliceosome

http://www.wikidata.org/entity/Q28776398

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Tertiary architecture of the Oceanobacillus iheyensis group II intron Activity of 3'-thioAMP derivatives as ribosomal P-site substrates.Functional identification of catalytic metal ion binding sites within RNA.Solution structure of domain 5 of a group II intron ribozyme reveals a new RNA motif X-ray Structures of U2 snRNA−Branchpoint Duplexes Containing Conserved Pseudouridines † ‡Coordination of divalent metal ions in the active site of poly(A)-specific ribonuclease Mitochondrial Mg(2+) homeostasis is critical for group II intron splicing in vivo A ribozyme selected from variants of U6 snRNA promotes 2',5'-branch formation Recent advances in the elucidation of the mechanisms of action of ribozymes RNA structure analysis of human spliceosomes reveals a compact 3D arrangement of snRNAs at the catalytic core.RNA-RNA interactions and pre-mRNA mislocalization as drivers of group II intron loss from nuclear genomes.A further investigation and reappraisal of the thio effect in the cleavage reaction catalyzed by a hammerhead ribozyme.Nuclear expression of a group II intron is consistent with spliceosomal intron ancestry.The use of divalent metal ions by type II topoisomerases.A tertiary interaction detected in a human U2-U6 snRNA complex assembled in vitro resembles a genetically proven interaction in yeast.The conserved central domain of yeast U6 snRNA: importance of U2-U6 helix Ia in spliceosome assembly.Characterization of the catalytic activity of U2 and U6 snRNAs New tertiary constraints between the RNA components of active yeast spliceosomes: a photo-crosslinking study.RNA catalyses nuclear pre-mRNA splicing RNA-protein interactions that regulate pre-mRNA splicing.Evidence for a group II intron-like catalytic triplex in the spliceosome A general and efficient approach for the construction of RNA oligonucleotides containing a 5'-phosphorothiolate linkage.Single-molecule analysis of protein-free U2-U6 snRNAs.Use of divalent metal ions in the DNA cleavage reaction of topoisomerase IV.The tertiary structure of group II introns: implications for biological function and evolution Studying metal ion binding properties of a three-way junction RNA by heteronuclear NMR.Human topoisomerase IIalpha uses a two-metal-ion mechanism for DNA cleavage.Conformational heterogeneity of the protein-free human spliceosomal U2-U6 snRNA complex Metal switch-controlled myosin II from Dictyostelium discoideum supports closure of nucleotide pocket during ATP binding coupled to detachment from actin filaments Use of divalent metal ions in the dna cleavage reaction of human type II topoisomerases.A glimpse into the active site of a group II intron and maybe the spliceosome, too.Metal ion interactions in the DNA cleavage/ligation active site of human topoisomerase IIalpha Identification of catalytic metal ion ligands in ribozymes.Metal ion catalysis during the exon-ligation step of nuclear pre-mRNA splicing: extending the parallels between the spliceosome and group II introns Active site constraints in the hydrolysis reaction catalyzed by bacterial RNase P: analysis of precursor tRNAs with a single 3'-S-phosphorothiolate internucleotide linkage Splicing of an intervening sequence by protein-free human snRNAs.Structural Insights into the Mechanism of Group II Intron Splicing.Visualizing the solvent-inaccessible core of a group II intron ribozyme Synthesis and biochemical application of 2'-O-methyl-3'-thioguanosine as a probe to explore group I intron catalysis.The linear form of a group II intron catalyzes efficient autocatalytic reverse splicing, establishing a potential for mobility.

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P2860

Metal ion catalysis during group II intron self-splicing: parallels with the spliceosome

http://www.wikidata.org/entity/Q28776398

description

1999 nî lūn-bûn

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1999 թուականի Յուլիսին հրատարակուած գիտական յօդուած

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1999 թվականի հուլիսին հրատարակված գիտական հոդված

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1999年の論文

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1999年論文

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1999年論文

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1999年論文

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1999年論文

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1999年論文

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1999年论文

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name

Metal ion catalysis during group II intron self-splicing: parallels with the spliceosome

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Metal ion catalysis during group II intron self-splicing: parallels with the spliceosome

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type

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Metal ion catalysis during group II intron self-splicing: parallels with the spliceosome

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Metal ion catalysis during group II intron self-splicing: parallels with the spliceosome

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Metal ion catalysis during group II intron self-splicing: parallels with the spliceosome

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Metal ion catalysis during group II intron self-splicing: parallels with the spliceosome

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Metal ion catalysis during group II intron self-splicing: parallels with the spliceosome

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P2093

E J Sontheimer

http://www.w3.org/2001/XMLSchema#string

J A Piccirilli

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P M Gordon

http://www.w3.org/2001/XMLSchema#string

P2860

A general two-metal-ion mechanism for catalytic RNA

Metal ion catalysis in the Tetrahymena ribozyme reaction

Why genes in pieces?

The recent origins of spliceosomal introns revisited.

The generality of self-splicing RNA: relationship to nuclear mRNA splicing.

Bridging sulfur substitutions in the analysis of pre-mRNA splicing.

Structure and activities of group II introns.

Branch nucleophile selection in pre-mRNA splicing: evidence for the bulged duplex model.

Catalytically critical nucleotide in domain 5 of a group II intron.

Evidence for two active sites in the spliceosome provided by stereochemistry of pre-mRNA splicing.

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13

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