Molecular evolution of SRP cycle components: functional implications
about
Getting on target: the archaeal signal recognition particleSaccharomyces SRP RNA secondary structures: a conserved S-domain and extended Alu-domain.The trypanosomatid signal recognition particle consists of two RNA molecules, a 7SL RNA homologue and a novel tRNA-like moleculeActivated GTPase movement on an RNA scaffold drives co-translational protein targetingLocalization of signal recognition particle RNA in the nucleolus of mammalian cells'RNA walk' a novel approach to study RNA-RNA interactions between a small RNA and its target.Archaeal protein translocation crossing membranes in the third domain of life.Neisseria gonorrhoeae PilA is an FtsY homologArchaea signal recognition particle shows the way.Protein transport via amino-terminal targeting sequences: common themes in diverse systems.In vivo analysis of an essential archaeal signal recognition particle in its native host.Structure of 4.5S RNA in the signal recognition particle of Escherichia coli as studied by enzymatic and chemical probing.The SRP9/14 subunit of the signal recognition particle (SRP) is present in more than 20-fold excess over SRP in primate cells and exists primarily free but also in complex with small cytoplasmic Alu RNAsA highly conserved nucleotide in the Alu domain of SRP RNA mediates translation arrest through high affinity binding to SRP9/14Expression, purification, and crystallography of the conserved methionine-rich domain of human signal recognition particle 54 kDa protein.All roads lead to Rome (but some may be harder to travel): SRP-independent translocation into the endoplasmic reticulum.Kinetics of cisplatin binding to short r(GG) containing miRNA mimics - influence of Na(+)versus K(+), temperature and hydrophobicity on reactivity.The Srp54 GTPase is essential for protein export in the fission yeast Schizosaccharomyces pombe.Bacillus subtilis histone-like protein, HBsu, is an integral component of a SRP-like particle that can bind the Alu domain of small cytoplasmic RNA.Reconstitution of the signal recognition particle of the halophilic archaeon Haloferax volcanii.The trypanosomatid Leptomonas collosoma 7SL RNA gene. Analysis of elements controlling its expression.Important role of the tetraloop region of 4.5S RNA in SRP binding to its receptor FtsY.The Escherichia coli SRP and SecB targeting pathways converge at the transloconYarrowia lipolytica SRP54 homolog and translocation of Kar2p.Domain structure, GTP-hydrolyzing activity and 7S RNA binding of Acidianus ambivalens ffh-homologous protein suggest an SRP-like complex in archaea.Deletion analysis of yeast Sec65p reveals a central domain that is sufficient for function in vivo.Heat shock inhibits release of the signal recognition particle from the endoplasmic reticulum in barley aleurone layers.Mapping the signal sequence-binding site on SRP reveals a significant role for the NG domain.The functioning of the SRP receptor FtsY in protein-targeting in E. coli is correlated with its ability to bind and hydrolyse GTP.
P2860
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P2860
Molecular evolution of SRP cycle components: functional implications
description
1994 nî lūn-bûn
@nan
1994 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
1994 թվականի հունիսին հրատարակված գիտական հոդված
@hy
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
name
Molecular evolution of SRP cycle components: functional implications
@ast
Molecular evolution of SRP cycle components: functional implications
@en
type
label
Molecular evolution of SRP cycle components: functional implications
@ast
Molecular evolution of SRP cycle components: functional implications
@en
prefLabel
Molecular evolution of SRP cycle components: functional implications
@ast
Molecular evolution of SRP cycle components: functional implications
@en
P2093
P2860
P356
P1476
Molecular evolution of SRP cycle components: functional implications
@en
P2093
P2860
P304
P356
10.1093/NAR/22.11.1933
P407
P577
1994-06-11T00:00:00Z