Structural basis for small molecule targeting of the programmed death ligand 1 (PD-L1)
about
Structural basis of checkpoint blockade by monoclonal antibodies in cancer immunotherapyThe antitumor activity and preliminary modeling on the potential mechanism of action of human peroxiredoxin-5.Design of short peptides to block BTLA/HVEM interactions for promoting anticancer T-cell responses.An unexpected N-terminal loop in PD-1 dominates binding by nivolumab.Discovery of peptide inhibitors targeting human programmed death 1 (PD-1) receptorStructural basis of a novel PD-L1 nanobody for immune checkpoint blockade.Small-molecule antagonists of the immune checkpoint pathways: concept to clinic.Challenges in the design of reliable immuno-oncology mouse models to inform drug development.Relationship between expression of PD-L1 and tumor angiogenesis, proliferation, and invasion in glioma.Inhibitors of programmed cell death 1 (PD-1): a patent review (2010-2015).Crystal clear: visualizing the intervention mechanism of the PD-1/PD-L1 interaction by two cancer therapeutic monoclonal antibodies.Remarkably similar CTLA-4 binding properties of therapeutic ipilimumab and tremelimumab antibodies.Coinhibitory Receptor Expression and Immune Checkpoint Blockade: Maintaining a Balance in CD8+ T Cell Responses to Chronic Viral Infections and Cancer.Small-molecule inhibitors of PD-1/PD-L1 immune checkpoint alleviate the PD-L1-induced exhaustion of T-cells.PD-1/PD-L1 binding studies using microscale thermophoresis.Structural basis of the therapeutic anti-PD-L1 antibody atezolizumab.Distinct PD-L1 binding characteristics of therapeutic monoclonal antibody durvalumab.Bioactive Macrocyclic Inhibitors of the PD-1/PD-L1 Immune Checkpoint.Stabilization of protein-protein interactions in drug discovery.Small Molecules Drive Big Improvements in Immuno-Oncology Therapies.A versatile T cell-based assay to assess therapeutic antigen-specific PD-1-targeted approaches.
P2860
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P2860
Structural basis for small molecule targeting of the programmed death ligand 1 (PD-L1)
description
2016 nî lūn-bûn
@nan
2016 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2016 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2016年の論文
@ja
2016年論文
@yue
2016年論文
@zh-hant
2016年論文
@zh-hk
2016年論文
@zh-mo
2016年論文
@zh-tw
2016年论文
@wuu
name
Structural basis for small molecule targeting of the programmed death ligand 1 (PD-L1)
@ast
Structural basis for small molecule targeting of the programmed death ligand 1 (PD-L1)
@en
type
label
Structural basis for small molecule targeting of the programmed death ligand 1 (PD-L1)
@ast
Structural basis for small molecule targeting of the programmed death ligand 1 (PD-L1)
@en
prefLabel
Structural basis for small molecule targeting of the programmed death ligand 1 (PD-L1)
@ast
Structural basis for small molecule targeting of the programmed death ligand 1 (PD-L1)
@en
P2093
P2860
P50
P3181
P356
P1433
P1476
Structural basis for small molecule targeting of the programmed death ligand 1 (PD-L1)
@en
P2093
Bartosz J Zieba
Bogdan Musielak
Katarzyna Guzik
Krzysztof M Zak
Tad A Holak
P2860
P304
30323-30335
P3181
P356
10.18632/ONCOTARGET.8730
P407
P577
2016-05-01T00:00:00Z