Structural basis for inhibition of the insulin receptor by the adaptor protein Grb14
about
Molecular basis of signaling specificity of insulin and IGF receptors: neglected corners and recent advancesForty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysisInhibition of the EGF receptor by binding of MIG6 to an activating kinase domain interfaceGrowth factor receptor-bound protein 14: a new modulator of photoreceptor-specific cyclic-nucleotide-gated channelGrb14 inhibits FGF receptor signaling through the regulation of PLCγ recruitment and activationInteraction with Grb14 results in site-specific regulation of tyrosine phosphorylation of the insulin receptorRegulation of MBK-2/DYRK by CDK-1 and the pseudophosphatases EGG-4 and EGG-5 during the oocyte-to-embryo transitionPhosphorylation of Grb14 BPS domain by GSK-3 correlates with complex forming of Grb14 and insulin receptorGenetics of Insulin Resistance and the Metabolic SyndromeThe role of small adaptor proteins in the control of oncogenic signalingr driven by tyrosine kinases in human cancerRegulation of insulin and type 1 insulin-like growth factor signaling and action by the Grb10/14 and SH2B1/B2 adaptor proteinsGrb7 SH2 domain structure and interactions with a cyclic peptide inhibitor of cancer cell migration and proliferationStructural and functional studies of the Ras-associating and pleckstrin-homology domains of Grb10 and Grb14Structural Basis for the Interaction between the Growth Factor-binding Protein GRB10 and the E3 Ubiquitin Ligase NEDD4SOCS3 binds specific receptor–JAK complexes to control cytokine signaling by direct kinase inhibitionStructural Basis for the Interaction of the Adaptor Protein Grb14 with Activated RasThe language of SH2 domain interactions defines phosphotyrosine-mediated signal transductionCompartmentalization and in vivo insulin-induced translocation of the insulin-signaling inhibitor Grb14 in rat liverThe transcriptome of the bowhead whale Balaena mysticetus reveals adaptations of the longest-lived mammalMolecular determinants of Grb14-mediated inhibition of insulin signaling.Pleiotropic genes for metabolic syndrome and inflammationEGF-induced Grb7 recruits and promotes Ras activity essential for the tumorigenicity of Sk-Br3 breast cancer cells.Dimeric switch of Hakai-truncated monomers during substrate recognition: insights from solution studies and NMR structureThe cell migration protein Grb7 associates with transcriptional regulator FHL2 in a Grb7 phosphorylation-dependent manner.An epigenetic map of age-associated autosomal loci in northern European families at high risk for the metabolic syndromeHow IGF-1 activates its receptor.Phosphorylated Grb14 is an endogenous inhibitor of retinal protein tyrosine phosphatase 1B, and light-dependent activation of Src phosphorylates Grb14.Towards breed formation by island model divergence in Korean cattleMice with a disruption of the imprinted Grb10 gene exhibit altered body composition, glucose homeostasis, and insulin signaling during postnatal life.Genetics of non-conventional lipoprotein fractions.Genome-wide meta-analysis uncovers novel loci influencing circulating leptin levelsThe insulin receptor: both a prototypical and atypical receptor tyrosine kinase.A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistanceReceptor tyrosine kinases: mechanisms of activation and signaling.A Molecular Signature of Myalgia in Myotonic Dystrophy 2Generalization of adiposity genetic loci to US Hispanic women.Novel Grb14-Mediated Cross Talk between Insulin and p62/Nrf2 Pathways Regulates Liver Lipogenesis and Selective Insulin Resistance.The ErbB kinase domain: structural perspectives into kinase activation and inhibition.Dual ablation of Grb10 and Grb14 in mice reveals their combined role in regulation of insulin signaling and glucose homeostasisAn electrostatic selection mechanism controls sequential kinase signaling downstream of the T cell receptor.
P2860
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P2860
Structural basis for inhibition of the insulin receptor by the adaptor protein Grb14
description
2005 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2005
@ast
im Oktober 2005 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
wetenschappelijk artikel (gepubliceerd op 2005/10/28)
@nl
наукова стаття, опублікована в жовтні 2005
@uk
مقالة علمية (نشرت في 28-10-2005)
@ar
name
Structural basis for inhibition of the insulin receptor by the adaptor protein Grb14
@ast
Structural basis for inhibition of the insulin receptor by the adaptor protein Grb14
@en
type
label
Structural basis for inhibition of the insulin receptor by the adaptor protein Grb14
@ast
Structural basis for inhibition of the insulin receptor by the adaptor protein Grb14
@en
prefLabel
Structural basis for inhibition of the insulin receptor by the adaptor protein Grb14
@ast
Structural basis for inhibition of the insulin receptor by the adaptor protein Grb14
@en
P2093
P2860
P921
P3181
P1433
P1476
Structural basis for inhibition of the insulin receptor by the adaptor protein Grb14
@en
P2093
Ilana Gimpelevich
Lowenna J. Holt
Rafael S. Depetris
Roger J. Daly
Stevan R. Hubbard
P2860
P304
P356
10.1016/J.MOLCEL.2005.09.001
P577
2005-10-28T00:00:00Z