Powerful bivariate genome-wide association analyses suggest the SOX6 gene influencing both obesity and osteoporosis phenotypes in males
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Evidence for pleiotropic factors in genetics of the musculoskeletal systemHow pleiotropic genetics of the musculoskeletal system can inform genomics and phenomics of agingFuture of osteoporosis genetics: enhancing genome-wide association studiesAssociation between VDR and ESR1 gene polymorphisms with bone and obesity phenotypes in Chinese male nuclear families.Genome-wide association studies identified multiple genetic loci for body size at four growth stages in Chinese Holstein cattleMultivariate generalized multifactor dimensionality reduction to detect gene-gene interactionsGenome wide association studies for milk production traits in Chinese Holstein population.Refined QTLs of osteoporosis-related traits by linkage analysis with genome-wide SNPs: Framingham SHAReSynopsis and meta-analysis of genetic association studies in osteoporosis for the focal adhesion family genes: the CUMAGAS-OSTEOporosis information system.Genome-wide Association Studies for Osteoporosis: A 2013 Update.Bivariate genome-wide association analyses of femoral neck bone geometry and appendicular lean massThe fat mass and obesity associated gene, FTO, is also associated with osteoporosis phenotypesGenetic variants in the SOX6 gene are associated with bone mineral density in both Caucasian and Chinese populations.Genomewide linkage and peakwide association analyses of carotid plaque in Caribbean HispanicsPolymorphisms in the inflammatory genes CIITA, CLEC16A and IFNG influence BMD, bone loss and fracture in elderly women.Bone mineral density-associated polymorphisms are associated with obesity-related traits in Korean adults in a sex-dependent mannerBivariate genome-wide association analyses identified genes with pleiotropic effects for femoral neck bone geometry and age at menarche.The genetics of bone loss: challenges and prospectsGene expression profiles in human and mouse primary cells provide new insights into the differential actions of vitamin D3 metabolites.Variation in the MC4R gene is associated with bone phenotypes in elderly Swedish women.Regulation of Sox6 by cyclin dependent kinase 5 in brainA comparison of multivariate genome-wide association methods.Efficient multiple-trait association and estimation of genetic correlation using the matrix-variate linear mixed model.Sry-box (Sox) transcription factors in gastrointestinal physiology and disease.Genome-wide association study using family-based cohorts identifies the WLS and CCDC170/ESR1 loci as associated with bone mineral density.Molecular genetic studies of gene identification for osteoporosis: the 2009 updateThe genetic pleiotropy of musculoskeletal aging.Endochondral ossification pathway genes and postmenopausal osteoporosis: Association and specific allele related serum bone sialoprotein levels in Han ChineseSuggestion of GLYAT gene underlying variation of bone size and body lean mass as revealed by a bivariate genome-wide association studyGenome-wide approaches for identifying genetic risk factors for osteoporosis.QTL-based association analyses reveal novel genes influencing pleiotropy of metabolic syndrome (MetS).Genome-wide linkage scan for quantitative trait loci underlying normal variation in heel bone ultrasound measures.Association of single nucleotide polymorphism Rs2236518 in PRDM16 gene with BMI in Chinese males.Analysis of multiple related phenotypes in genome-wide association studies.GWAS of DNA methylation variation within imprinting control regions suggests parent-of-origin association.Global developmental delay, progressive relapsing-remitting parkinsonism, and spinal syrinx in a child with SOX6 mutation.A translational approach from an animal model identifies CD80 as a candidate gene for the study of bone phenotypes in postmenopausal women.Identification of Novel Potentially Pleiotropic Variants Associated With Osteoporosis and Obesity Using the cFDR Method.Hierarchical Association Coefficient Algorithm: New Method for Genome-Wide Association Study.Bivariate genome-wide association study suggests that the DARC gene influences lean body mass and age at menarche.
P2860
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P2860
Powerful bivariate genome-wide association analyses suggest the SOX6 gene influencing both obesity and osteoporosis phenotypes in males
description
2009 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique PLoS ONE
@fr
artículu científicu espublizáu en 2009
@ast
im August 2009 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
wetenschappelijk artikel (gepubliceerd op 2009/08/28)
@nl
наукова стаття, опублікована в серпні 2009
@uk
مقالة علمية (نشرت في 28-8-2009)
@ar
name
Powerful bivariate genome-wide ...... teoporosis phenotypes in males
@ast
Powerful bivariate genome-wide ...... teoporosis phenotypes in males
@en
type
label
Powerful bivariate genome-wide ...... teoporosis phenotypes in males
@ast
Powerful bivariate genome-wide ...... teoporosis phenotypes in males
@en
prefLabel
Powerful bivariate genome-wide ...... teoporosis phenotypes in males
@ast
Powerful bivariate genome-wide ...... teoporosis phenotypes in males
@en
P2093
P2860
P50
P921
P1433
P1476
Powerful bivariate genome-wide ...... teoporosis phenotypes in males
@en
P2093
Liang Wang
Robert R. Recker
Xiao-Gang Liu
Yao-Zhong Liu
Yin-Ping Zhang
Yu-Fang Pei
P2860
P356
10.1371/JOURNAL.PONE.0006827
P407
P577
2009-08-28T00:00:00Z