Efficient generation of a biallelic knockout in pigs using zinc-finger nucleases
about
Repeatable construction method for engineered zinc finger nuclease based on overlap extension PCR and TA-cloningGenome-scale engineering for systems and synthetic biologyTargeting DNA With Fingers and TALENsPrecision editing of large animal genomesGene targeting, genome editing: from Dolly to editorsEngineering large animal models of human diseaseGenome-editing tools for stem cell biologyKidney xenotransplantationClinical lung xenotransplantation--what donor genetic modifications may be necessary?Genetics in non-genetic model systemsCurrent progress of genetically engineered pig models for biomedical researchTransgenesis for pig modelsUse of the CRISPR/Cas9 system to produce genetically engineered pigs from in vitro-derived oocytes and embryosGeneration of heterozygous fibrillin-1 mutant cloned pigs from genome-edited foetal fibroblastsZFN, TALEN, and CRISPR/Cas-based methods for genome engineeringFactors influencing the efficiency of generating genetically engineered pigs by nuclear transfer: multi-factorial analysis of a large data set.Production of cloned pigs with targeted attenuation of gene expression.Zinc finger nuclease mediated knockout of ADP-dependent glucokinase in cancer cell lines: effects on cell survival and mitochondrial oxidative metabolism.Generation of α-1,3-galactosyltransferase knocked-out transgenic cloned pigs with knocked-in five human genesEngraftment of human iPS cells and allogeneic porcine cells into pigs with inactivated RAG2 and accompanying severe combined immunodeficiency.Production of biallelic CMP-Neu5Ac hydroxylase knock-out pigsProduction of Mutated Porcine Embryos Using Zinc Finger Nucleases and a Reporter-based Cell Enrichment SystemDerivation and characterization of mouse embryonic stem cells from permissive and nonpermissive strains.Double knockout pigs deficient in N-glycolylneuraminic acid and galactose α-1,3-galactose reduce the humoral barrier to xenotransplantation.Reduced binding of human antibodies to cells from GGTA1/CMAH KO pigs.The role of genetically engineered pigs in xenotransplantation research.The production of multi-transgenic pigs: update and perspectives for xenotransplantation.Heritable targeted inactivation of myostatin gene in yellow catfish (Pelteobagrus fulvidraco) using engineered zinc finger nucleases.Targeted gene knockout in chickens mediated by TALENsHigh frequency targeted mutagenesis using engineered endonucleases and DNA-end processing enzymes.Efficient bi-allelic gene knockout and site-specific knock-in mediated by TALENs in pigs.Zinc-finger nuclease mediated disruption of Rag1 in the LEW/Ztm rat.Potential of primary kidney cells for somatic cell nuclear transfer mediated transgenesis in pig.Genetic Dissection of the Host Tropism of Human-Tropic Pathogens.International regulatory landscape and integration of corrective genome editing into in vitro fertilization.Production of multiple transgenic Yucatan miniature pigs expressing human complement regulatory factors, human CD55, CD59, and H-transferase genesHigh efficiency In Vivo genome engineering with a simplified 15-RVD GoldyTALEN designGeneration of interleukin-2 receptor gamma gene knockout pigs from somatic cells genetically modified by zinc finger nuclease-encoding mRNAEfficient generation of gene-modified pigs via injection of zygote with Cas9/sgRNA.Highly efficient generation of GGTA1 biallelic knockout inbred mini-pigs with TALENs
P2860
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P2860
Efficient generation of a biallelic knockout in pigs using zinc-finger nucleases
description
2011 nî lūn-bûn
@nan
2011 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Efficient generation of a biallelic knockout in pigs using zinc-finger nucleases
@ast
Efficient generation of a biallelic knockout in pigs using zinc-finger nucleases
@en
type
label
Efficient generation of a biallelic knockout in pigs using zinc-finger nucleases
@ast
Efficient generation of a biallelic knockout in pigs using zinc-finger nucleases
@en
prefLabel
Efficient generation of a biallelic knockout in pigs using zinc-finger nucleases
@ast
Efficient generation of a biallelic knockout in pigs using zinc-finger nucleases
@en
P2093
P2860
P3181
P356
P1476
Efficient generation of a biallelic knockout in pigs using zinc-finger nucleases
@en
P2093
A. Lucas-Hahn
A.-L. Queisser
B. Petersen
G. J. Cost
H. Niemann
J. Hauschild
J. W. Carnwath
P. D. Gregory
R. Schwinzer
P2860
P304
12013-12017
P3181
P356
10.1073/PNAS.1106422108
P407
P577
2011-07-05T00:00:00Z