Elf5 inhibits the epithelial–mesenchymal transition in mammary gland development and breast cancer metastasis by transcriptionally repressing Snail2
about
Developmental signaling pathways regulating mammary stem cells and contributing to the etiology of triple-negative breast cancerTargeting Breast Cancer MetastasisCrosstalk of the Insulin-Like Growth Factor Receptor with the Wnt Signaling Pathway in Breast CancerTranscriptional control of cancer metastasisMammary stem cells and the differentiation hierarchy: current status and perspectivesRegulation of mesenchymal phenotype by MicroRNAs in cancerELF5 Drives Lung Metastasis in Luminal Breast Cancer through Recruitment of Gr1+ CD11b+ Myeloid-Derived Suppressor CellsD-type Cyclins are important downstream effectors of cytokine signaling that regulate the proliferation of normal and neoplastic mammary epithelial cells.Distinctive properties of metastasis-initiating cellsMammary morphogenesis and regeneration require the inhibition of EMT at terminal end buds by Ovol2 transcriptional repressorELF5 isoform expression is tissue-specific and significantly altered in cancer.Prolactin cooperates with loss of p53 to promote claudin-low mammary carcinomasCPEB1 promotes differentiation and suppresses EMT in mammary epithelial cellsMinireview: prolactin regulation of adult stem cellsFoxa1 is essential for mammary duct formation.Direct endothelial junction restoration results in significant tumor vascular normalization and metastasis inhibition in miceBRCA1 haploinsufficiency cell-autonomously activates RANKL expression and generates denosumab-responsive breast cancer-initiating cells.Ovol proteins: guardians against EMT during epithelial differentiationConcise review: breast cancer stem cells: regulatory networks, stem cell niches, and disease relevanceThe microRNA-23b/27b/24 cluster promotes breast cancer lung metastasis by targeting metastasis-suppressive gene prosaposin.The impact of microRNA-mediated PI3K/AKT signaling on epithelial-mesenchymal transition and cancer stemness in endometrial cancer.Integrin αvβ3 drives slug activation and stemness in the pregnant and neoplastic mammary gland.A therapeutically targetable mechanism of BCR-ABL-independent imatinib resistance in chronic myeloid leukemia.ΔNp63 promotes stem cell activity in mammary gland development and basal-like breast cancer by enhancing Fzd7 expression and Wnt signalling.Multilayer control of the EMT master regulators.p38 MAPK inhibits breast cancer metastasis through regulation of stromal expansion.The mammary cellular hierarchy and breast cancer.The ETS family of oncogenic transcription factors in solid tumours.Expression profiling of migrated and invaded breast cancer cells predicts early metastatic relapse and reveals Krüppel-like factor 9 as a potential suppressor of invasive growth in breast cancer.Modulation of tumor fatty acids, through overexpression or loss of thyroid hormone responsive protein spot 14 is associated with altered growth and metastasis.RUNX1, a transcription factor mutated in breast cancer, controls the fate of ER-positive mammary luminal cells.Musashi proteins are post-transcriptional regulators of the epithelial-luminal cell statePDGFRα and β play critical roles in mediating Foxq1-driven breast cancer stemness and chemoresistance.Epigenetic regulation of Elf5 is associated with epithelial-mesenchymal transition in urothelial cancer.Analysis of the TGFβ-induced program in primary airway epithelial cells shows essential role of NF-κB/RelA signaling network in type II epithelial mesenchymal transition.Paracrine Met signaling triggers epithelial-mesenchymal transition in mammary luminal progenitors, affecting their fateRewiring of an epithelial differentiation factor, miR-203, to inhibit human squamous cell carcinoma metastasis.MicroRNA-93 Promotes Epithelial-Mesenchymal Transition of Endometrial Carcinoma CellsGene regulatory network underlying the immortalization of epithelial cells.TEL2 suppresses metastasis by down-regulating SERPINE1 in nasopharyngeal carcinoma.
P2860
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P2860
Elf5 inhibits the epithelial–mesenchymal transition in mammary gland development and breast cancer metastasis by transcriptionally repressing Snail2
description
2012 nî lūn-bûn
@nan
2012 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Elf5 inhibits the epithelial–m ...... criptionally repressing Snail2
@ast
Elf5 inhibits the epithelial–m ...... criptionally repressing Snail2
@en
type
label
Elf5 inhibits the epithelial–m ...... criptionally repressing Snail2
@ast
Elf5 inhibits the epithelial–m ...... criptionally repressing Snail2
@en
prefLabel
Elf5 inhibits the epithelial–m ...... criptionally repressing Snail2
@ast
Elf5 inhibits the epithelial–m ...... criptionally repressing Snail2
@en
P2093
P2860
P50
P3181
P356
P1433
P1476
Elf5 inhibits the epithelial–m ...... criptionally repressing Snail2
@en
P2093
Bruce G. Haffty
Dino Amadori
Julie Hwang
Kirsten Smalley
Mario Andres Blanco
Qifeng Yang
Rose-Anne Romano
Rumela Chakrabarti
Satrajit Sinha
P2860
P2888
P304
P3181
P356
10.1038/NCB2607
P577
2012-10-21T00:00:00Z
P5875
P6179
1018595871