cGMP Signals Modulate cAMP Levels in a Compartment-Specific Manner to Regulate Catecholamine-Dependent Signaling in Cardiac Myocytes
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The inotropic effect of the active metabolite of levosimendan, OR-1896, is mediated through inhibition of PDE3 in rat ventricular myocardiumPhosphodiesterase 9A controls nitric-oxide-independent cGMP and hypertrophic heart diseasePhosphodiesterase Inhibition and Regulation of Dopaminergic Frontal and Striatal Functioning: Clinical ImplicationsImaging alterations of cardiomyocyte cAMP microdomains in diseaseMolecular regulation of NKCC2 in the thick ascending limbPhosphodiesterases maintain signaling fidelity via compartmentalization of cyclic nucleotidesSpatial control of cAMP signalling in health and diseaseInhibition of type 5 phosphodiesterase counteracts β2-adrenergic signalling in beating cardiomyocytesCross-regulation of Phosphodiesterase 1 and Phosphodiesterase 2 Activities Controls Dopamine-mediated Striatal α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid (AMPA) Receptor TraffickingPDE2A2 regulates mitochondria morphology and apoptotic cell death via local modulation of cAMP/PKA signallingAttenuated response of L-type calcium current to nitric oxide in atrial fibrillation.FRET biosensor uncovers cAMP nano-domains at β-adrenergic targets that dictate precise tuning of cardiac contractility.Advances in targeting cyclic nucleotide phosphodiesterasesRole of phosphodiesterase 2 in growth and invasion of human malignant melanoma cellsCyclic nucleotide phosphodiesterases: important signaling modulators and therapeutic targets.Soluble guanylate cyclase is required for systemic vasodilation but not positive inotropy induced by nitroxyl in the mouse.sGC{alpha}1 mediates the negative inotropic effects of NO in cardiac myocytes independent of changes in calcium handlingAgents increasing cyclic GMP amplify 5-HT4-elicited positive inotropic response in failing rat cardiac ventricle.Plasma membrane calcium pump (PMCA4)-neuronal nitric-oxide synthase complex regulates cardiac contractility through modulation of a compartmentalized cyclic nucleotide microdomain.Cardiac role of cyclic-GMP hydrolyzing phosphodiesterase type 5: from experimental models to clinical trials.Pathological cardiac hypertrophy alters intracellular targeting of phosphodiesterase type 5 from nitric oxide synthase-3 to natriuretic peptide signaling.PKA and PDE4D3 anchoring to AKAP9 provides distinct regulation of cAMP signals at the centrosome.Roles of phosphodiesterases in the regulation of the cardiac cyclic nucleotide cross-talk signaling networkSERCA Cys674 sulphonylation and inhibition of L-type Ca2+ influx contribute to cardiac dysfunction in endotoxemic mice, independent of cGMP synthesis.The NO/cGMP pathway inhibits transient cAMP signals through the activation of PDE2 in striatal neurons.Interactions of Calcium Fluctuations during Cardiomyocyte Contraction with Real-Time cAMP Dynamics Detected by FRET.Clinical and molecular genetics of the phosphodiesterases (PDEs).Phosphodiesterases and subcellular compartmentalized cAMP signaling in the cardiovascular system.Phosphodiesterases and cyclic GMP regulation in heart muscle.Compartmentation of cAMP signalling in cardiomyocytes in health and disease.Biophysical techniques for detection of cAMP and cGMP in living cells.Novel approaches and opportunities for cardioprotective signaling through 3',5'-cyclic guanosine monophosphate manipulation.The cGMP/PKG pathway as a common mediator of cardioprotection: translatability and mechanism.β-adrenergic receptor signalling and its functional consequences in the diseased heart.Mechanisms of the cyclic nucleotide cross-talk signaling network in cardiac L-type calcium channel regulation.Dysregulation of Neuronal Ca2+ Channel Linked to Heightened Sympathetic Phenotype in Prohypertensive StatesIdentification of a novel microRNA important for melanogenesis in alpaca (Vicugna pacos).Phosphodiesterases 3 and 4 Differentially Regulate the Funny Current, If, in Mouse Sinoatrial Node MyocytesNon-genomic effects of spironolactone and eplerenone in cardiomyocytes of neonatal Wistar rats: do they evoke cardioprotective pathways?Differential regulation of cardiac excitation-contraction coupling by cAMP phosphodiesterase subtypes.
P2860
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P2860
cGMP Signals Modulate cAMP Levels in a Compartment-Specific Manner to Regulate Catecholamine-Dependent Signaling in Cardiac Myocytes
description
2011 nî lūn-bûn
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2011 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2011年の論文
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2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
cGMP Signals Modulate cAMP Lev ...... Signaling in Cardiac Myocytes
@ast
cGMP Signals Modulate cAMP Lev ...... Signaling in Cardiac Myocytes
@en
type
label
cGMP Signals Modulate cAMP Lev ...... Signaling in Cardiac Myocytes
@ast
cGMP Signals Modulate cAMP Lev ...... Signaling in Cardiac Myocytes
@en
prefLabel
cGMP Signals Modulate cAMP Lev ...... Signaling in Cardiac Myocytes
@ast
cGMP Signals Modulate cAMP Lev ...... Signaling in Cardiac Myocytes
@en
P2093
P2860
P50
P3181
P1433
P1476
cGMP signals modulate cAMP lev ...... signaling in cardiac myocytes
@en
P2093
Anna Terrin
Anna Zoccarato
Frank Gesellchen
Godfrey Smith
Laura Ashley Fields
Marco Berrera
Margaret Anne Craig
Nicoletta Concetta Surdo
P2860
P304
P3181
P356
10.1161/CIRCRESAHA.110.230698
P577
2011-02-17T00:00:00Z