Activation of a novel estrogen receptor, GPER, is cardioprotective in male and female rats
about
G-protein-coupled receptor 30 interacts with receptor activity-modifying protein 3 and confers sex-dependent cardioprotectionActivation of GPER Induces Differentiation and Inhibition of Coronary Artery Smooth Muscle Cell ProliferationHeart Disease in Women: Unappreciated Challenges, GPER as a New TargetSex-based differences in cardiac ischaemic injury and protection: therapeutic implicationsMaxiK channel and cell signallingThe G-protein-coupled estrogen receptor GPER in health and diseaseRole of estrogen in diastolic dysfunctionEstrogen biology: new insights into GPER function and clinical opportunitiesEstrogens in Male PhysiologyMechanistic Pathways of Sex Differences in Cardiovascular Disease.Rapid changes in cardiac myofilament function following the acute activation of estrogen receptor-alpha.A novel estrogen receptor GPER inhibits mitochondria permeability transition pore opening and protects the heart against ischemia-reperfusion injury.Role of Nongenomic Signaling Pathways Activated by Aldosterone During Cardiac Reperfusion Injury.Adenosine A1 receptor activation increases myocardial protein S-nitrosothiols and elicits protection from ischemia-reperfusion injury in male and female heartsProtein Kinases as Drug Development Targets for Heart Disease TherapyAttenuation of salt-induced cardiac remodeling and diastolic dysfunction by the GPER agonist G-1 in female mRen2.Lewis rats.Estrogen-mediated renoprotection following cardiac arrest and cardiopulmonary resuscitation is robust to GPR30 gene deletionGPER/GPR30 and Regulation of Vascular Tone and Blood Pressure.Oestrogen prevents cardiomyocyte apoptosis by suppressing p38α-mediated activation of p53 and by down-regulating p53 inhibition on p38β.Evidence that the G protein-coupled membrane receptor GPR30 contributes to the cardiovascular actions of estrogen.Deletion of G protein-coupled estrogen receptor increases endothelial vasoconstrictionHeterogeneity in MT1-MMP activity with ischemia-reperfusion and previous myocardial infarction: relation to regional myocardial function.Estrogen receptor activation and cardioprotection in ischemia reperfusion injury.Chronic activation of the G protein-coupled receptor 30 with agonist G-1 attenuates heart failure.What have we learned about GPER function in physiology and disease from knockout mice?Obligatory role for GPER in cardiovascular aging and disease.A common hypofunctional genetic variant of GPER is associated with increased blood pressure in women.Neuroprotective actions of estradiol and novel estrogen analogs in ischemia: translational implicationsGPER mediates cardiotropic effects in spontaneously hypertensive rat hearts.Both GPER and membrane oestrogen receptor-α activation protect ventricular remodelling in 17β oestradiol-treated ovariectomized infarcted rats.Estrogen, hormonal replacement therapy and cardiovascular disease.G protein-coupled oestrogen receptor 1 (GPER1)/GPR30: a new player in cardiovascular and metabolic oestrogenic signallingUnraveling the mechanisms underlying the rapid vascular effects of steroids: sorting out the receptors and the pathways.Mechanism of cardioprotection: what can we learn from females?GPR30 decreases cardiac chymase/angiotensin II by inhibiting local mast cell number.Dilation of epicardial coronary arteries by the G protein-coupled estrogen receptor agonists G-1 and ICI 182,780.Activation of G protein-coupled estrogen receptor induces endothelium-independent relaxation of coronary artery smooth muscle.The G protein-coupled estrogen receptor GPER/GPR30 as a regulator of cardiovascular function.Activation of novel estrogen receptor GPER results in inhibition of cardiocyte apoptosis and cardioprotection.Activation of GPR30 inhibits cardiac fibroblast proliferation.
P2860
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P2860
Activation of a novel estrogen receptor, GPER, is cardioprotective in male and female rats
description
2009 nî lūn-bûn
@nan
2009 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Activation of a novel estrogen ...... ective in male and female rats
@ast
Activation of a novel estrogen ...... ective in male and female rats
@en
type
label
Activation of a novel estrogen ...... ective in male and female rats
@ast
Activation of a novel estrogen ...... ective in male and female rats
@en
prefLabel
Activation of a novel estrogen ...... ective in male and female rats
@ast
Activation of a novel estrogen ...... ective in male and female rats
@en
P2860
P3181
P1476
Activation of a novel estrogen ...... ective in male and female rats
@en
P2093
Elizabeth Murphy
P2860
P304
P3181
P356
10.1152/AJPHEART.00283.2009
P577
2009-08-28T00:00:00Z