WRN mutations in Werner syndrome

WRN mutations in Werner syndrome

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http://www.wikidata.org/entity/Q29395498
Asymmetry of DNA replication fork progression in Werner's syndromeCrystal structure of the HRDC domain of human Werner syndrome protein, WRNRecQ helicases: caretakers of the genomeMechanism of Werner DNA helicase: POT1 and RPA stimulates WRN to unwind beyond gaps in the translocating strand.WRN is recruited to damaged telomeres via its RQC domain and tankyrase1-mediated poly-ADP-ribosylation of TRF1.Clinical manifestations in a cohort of 41 Rothmund-Thomson syndrome patients.Suppression of genome instability by redundant S-phase checkpoint pathways in Saccharomyces cerevisiae.Identification and characterization of a Drosophila ortholog of WRN exonuclease that is required to maintain genome integrity.The role of cellular senescence in Werner syndrome: toward therapeutic intervention in human premature aging.Homozygosity for the WRN Helicase-Inactivating Variant, R834C, does not confer a Werner syndrome clinical phenotype.Human RECQ Helicase Pathogenic Variants, Population Variation and "Missing" Diseases.Modulation of Werner syndrome protein function by a single mutation in the conserved RecQ domain.The enzymatic activities of the Werner syndrome protein are disabled by the amino acid polymorphism R834C.Werner syndrome protein contains three structure-specific DNA binding domains.Introduction to Telomeres and Telomerase.
P2860

WRN mutations in Werner syndrome

Item
http://www.wikidata.org/entity/Q29395498
description
1999 թուականին հրատարակուած գիտական յօդուած
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1999 թվականին հրատարակված գիտական հոդված
@hy
article
@en
artikull shkencor
@sq
im Jahr 1999 veröffentlichter wissenschaftlicher Artikel
@de
wetenschappelijk artikel
@nl
наукова стаття, опублікована в 1999
@uk
مقالة علمية (نشرت عام 1999)
@ar
ലേഖനം
@ml
name
WRN mutations in Werner syndrome
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WRN mutations in Werner syndrome
@en
type
label
WRN mutations in Werner syndrome
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WRN mutations in Werner syndrome
@en
prefLabel
WRN mutations in Werner syndrome
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WRN mutations in Werner syndrome
@en
P1433
P1476
P2093
P2860
P304
P31
P356
P433
P478
P577
P356
P1433
P1476
WRN mutations in Werner syndrome
@en
P2093
P2860
P304
P31
P356
10.1002/(SICI)1098-1004(1999)13:4<271::AID-HUMU2>3.0.CO;2-Q
P433
P478
P577