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Genome-wide association study identifies 12 new susceptibility loci for primary biliary cirrhosis

Genome-wide association study identifies 12 new susceptibility loci for primary biliary cirrhosis

http://www.wikidata.org/entity/Q29417041

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TNF receptor 1 genetic risk mirrors outcome of anti-TNF therapy in multiple sclerosis Immunochip analyses identify a novel risk locus for primary biliary cirrhosis at 13q14, multiple independent associations at four established risk loci and epistasis between 1p31 and 7q32 risk variants Dense fine-mapping study identifies new susceptibility loci for primary biliary cirrhosis Xenobiotics and loss of tolerance in primary biliary cholangitis The TNF-family cytokine TL1A: from lymphocyte costimulator to disease co-conspirator Primary biliary cirrhosis: From bench to bedside The immunogenetics of primary biliary cirrhosis: A comprehensive review The X-factor in primary biliary cirrhosis: monosomy X and xenobiotics Primary biliary cirrhosis and liver transplantation Interferons in Sjögren's Syndrome: Genes, Mechanisms, and Effects Skewed Helper T-Cell Responses to IL-12 Family Cytokines Produced by Antigen-Presenting Cells and the Genetic Background in Behcet's Disease Primary biliary cirrhosis: Clinical and laboratory criteria for its diagnosis The genetics of complex cholestatic disorders Fine mapping and functional studies of risk variants for type 1 diabetes at chromosome 16p13.13 Cirrhosis and autoimmune liver disease: Current understanding Recent advances in the diagnosis and treatment of primary biliary cholangitis.The Immunogenetics of Autoimmune Cholestasis A novel sarcoidosis risk locus for Europeans on chromosome 11q13.1 Genome-wide association analysis identifies 11 risk variants associated with the asthma with hay fever phenotype A general framework for meta-analyzing dependent studies with overlapping subjects in association mapping Genome-wide association study identifies susceptibility loci for dengue shock syndrome at MICB and PLCE1 Genome-wide association study identifies loci on 12q24 and 13q32 associated with tetralogy of Fallot Genome-wide association study identifies TNFSF15 and POU2AF1 as susceptibility loci for primary biliary cirrhosis in the Japanese population A genome-wide association study identifies PLCL2 and AP3D1-DOT1L-SF3A2 as new susceptibility loci for myocardial infarction in Japanese Identification of two new loci at IL23R and RAB32 that influence susceptibility to leprosy Novel rheumatoid arthritis susceptibility locus at 22q12 identified in an extended UK genome-wide association study Does pressure cause liver cirrhosis? The sinusoidal pressure hypothesis.Integration of disease association and eQTL data using a Bayesian colocalisation approach highlights six candidate causal genes in immune-mediated diseases Implications of genome-wide association studies in novel therapeutics in primary biliary cirrhosis A genome-wide association study identifies six novel risk loci for primary biliary cholangitis.STAT4 knockout mice are more susceptible to concanavalin A-induced T-cell hepatitis.Identification of the functional variant driving ORMDL3 and GSDMB expression in human chromosome 17q12-21 in primary biliary cholangitis.Genetic Polymorphisms of Cytotoxic T-Lymphocyte Antigen 4 in Primary Biliary Cholangitis: A Meta-Analysis Why Doesn't Primary Biliary Cholangitis Respond to Immunosuppressive Medications?The Emerging Role of Soluble Adenylyl Cyclase in Primary Biliary Cholangitis.Impact of microbes on autoimmune diseases.Unraveling the regulatory mechanisms underlying tissue-dependent genetic variation of gene expression.Improved statistics for genome-wide interaction analysis.Shotgun proteomics: identification of unique protein profiles of apoptotic bodies from biliary epithelial cells IL-7 in human health and disease.

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Genome-wide association study identifies 12 new susceptibility loci for primary biliary cirrhosis

http://www.wikidata.org/entity/Q29417041

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2011 nî lūn-bûn

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2011 թուականի Մարտին հրատարակուած գիտական յօդուած

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2011 թվականի մարտին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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Nature Genetics

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Agnes W Muriithi

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Christopher S Franklin

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Darren B Day

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David E Jones

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Elizabeth F Wheater

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George F Mells

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Graeme J Alexander

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Heather J Cordell

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James A B Floyd

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James M Neuberger

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P2860

Cloning of a novel tumor necrosis factor-alpha-inducible primary response gene that is differentially expressed in development and capillary tube-like formation in vitro

Primary biliary cirrhosis associated with HLA, IL12A, and IL12RB2 variants

Down-regulation of DENN/MADD, a TNF receptor binding protein, correlates with neuronal cell death in Alzheimer's disease brain and hippocampal neurons

A unified approach to genotype imputation and haplotype-phase inference for large data sets of trios and unrelated individuals

Genome-wide association study of ulcerative colitis identifies three new susceptibility loci, including the HNF4A region

PLINK: a tool set for whole-genome association and population-based linkage analyses

Principal components analysis corrects for stratification in genome-wide association studies

NF-kappaB regulation in the immune system

Genome-wide meta-analyses identify three loci associated with primary biliary cirrhosis

A genome-wide association study of global gene expression

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329-332

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43161

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10.1038/NG.789

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4

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43

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Leena Peltonen-Palotie

Christopher J. Hammond

Katherine I. Morley

Carl A Anderson

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2011-03-13T00:00:00Z

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50377256

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1003307476

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21399635

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genome-wide association study

susceptibility locus

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3071550

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