A nontoxic pain killer designed by modeling of pathological receptor conformations.
about
Polyglycerol-opioid conjugate produces analgesia devoid of side effectsBreaking barriers to novel analgesic drug development.Peripheral Interaction of Resolvin D1 and E1 with Opioid Receptor Antagonists for Antinociception in Inflammatory Pain in Rats.Basic/Translational Development of Forthcoming Opioid- and Nonopioid-Targeted Pain Therapeutics.Designing Safer Analgesics via μ-Opioid Receptor Pathways.Therapies and mechanisms of opioid withdrawal.The opioid epidemic: a central role for the blood brain barrier in opioid analgesia and abuse.Structure of the Nanobody-Stabilized Active State of the Kappa Opioid Receptor.Natural product modulators of human sensations and mood: molecular mechanisms and therapeutic potential.Towards an Effective Peripheral Visceral Analgesic: Responding to the National Opioid Crisis.Inhibitory Gi/O-coupled receptors in somatosensory neurons: Potential therapeutic targets for novel analgesics.Peripherally Acting μ-Opioid Receptor Agonists Attenuate Ongoing Pain-associated Behavior and Spontaneous Neuronal Activity after Nerve Injury in Rats.Biomolecular Simulations Under Realistic Macroscopic Salt Conditions.Opioid receptor signaling, analgesic and side effects induced by a computationally designed pH-dependent agonist.Inner Workings: Safer opioids may be on the horizon, but mitigating addiction is a long shot
P2860
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P2860
A nontoxic pain killer designed by modeling of pathological receptor conformations.
description
2017 nî lūn-bûn
@nan
2017 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2017 թվականի մարտին հրատարակված գիտական հոդված
@hy
2017年の論文
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2017年論文
@yue
2017年論文
@zh-hant
2017年論文
@zh-hk
2017年論文
@zh-mo
2017年論文
@zh-tw
2017年论文
@wuu
name
A nontoxic pain killer designed by modeling of pathological receptor conformations.
@ast
A nontoxic pain killer designed by modeling of pathological receptor conformations.
@en
type
label
A nontoxic pain killer designed by modeling of pathological receptor conformations.
@ast
A nontoxic pain killer designed by modeling of pathological receptor conformations.
@en
prefLabel
A nontoxic pain killer designed by modeling of pathological receptor conformations.
@ast
A nontoxic pain killer designed by modeling of pathological receptor conformations.
@en
P2860
P50
P356
P1433
P1476
A nontoxic pain killer designed by modeling of pathological receptor conformations.
@en
P2093
P2860
P304
P356
10.1126/SCIENCE.AAI8636
P407
P50
P577
2017-03-01T00:00:00Z