Targeted disruption of the c-src proto-oncogene leads to osteopetrosis in mice
about
P1343
Comprehensive analysis of interactions between the Src-associated protein in mitosis of 68 kDa and the human Src-homology 3 proteomeAblation of the Sam68 RNA binding protein protects mice from age-related bone lossAbsence of basement membranes after targeting the LAMC1 gene results in embryonic lethality due to failure of endoderm differentiationC-terminal Src kinase associates with ligand-stimulated insulin-like growth factor-I receptorNegative Regulation of BRCA1 Gene Expression by HMGA1 Proteins Accounts for the Reduced BRCA1 Protein Levels in Sporadic Breast CarcinomaCbl associates with Pyk2 and Src to regulate Src kinase activity, alpha(v)beta(3) integrin-mediated signaling, cell adhesion, and osteoclast motilityTumor formation and inactivation of RIZ1, an Rb-binding member of a nuclear protein-methyltransferase superfamilyCoordinate interactions of Csk, Src, and Syk kinases with [alpha]IIb[beta]3 initiate integrin signaling to the cytoskeletonCbl-mediated degradation of Lyn and Fyn induced by constitutive fibroblast growth factor receptor-2 activation supports osteoblast differentiationc-Src control of chloride channel support for osteoclast HCl transport and bone resorptionRegulation of cytochrome c oxidase activity by c-Src in osteoclastsSrc kinase activation by direct interaction with the integrin beta cytoplasmic domainRegulation of c-Src by binding to the PDZ domain of AF-6Activation of Src family kinases by colony stimulating factor-1, and their association with its receptorIntroduction of p130cas signaling complex formation upon integrin-mediated cell adhesion: a role for Src family kinasesPTP-1B is an essential positive regulator of platelet integrin signalingCooperation between integrin alphavbeta3 and VEGFR2 in angiogenesisTks5-dependent formation of circumferential podosomes/invadopodia mediates cell-cell fusionSrc phosphorylation of the epidermal growth factor receptor at novel sites mediates receptor interaction with Src and P85 alphaMouse disabled (mDab1): a Src binding protein implicated in neuronal developmentRequirement of the mouse I-mfa gene for placental development and skeletal patterningMitf and Tfe3, two members of the Mitf-Tfe family of bHLH-Zip transcription factors, have important but functionally redundant roles in osteoclast development.Receptor activator of NF-kappaB ligand (RANKL) activates TAK1 mitogen-activated protein kinase kinase kinase through a signaling complex containing RANK, TAB2, and TRAF6Loss of Apc heterozygosity and abnormal tissue building in nascent intestinal polyps in mice carrying a truncated Apc geneFormin binding proteins bear WWP/WW domains that bind proline-rich peptides and functionally resemble SH3 domainsTargeted mutation in the neurotrophin-3 gene results in loss of muscle sensory neuronsRANK is essential for osteoclast and lymph node developmentA comprehensive manually curated reaction map of RANKL/RANK-signaling pathwayNoggin-mediated antagonism of BMP signaling is required for growth and patterning of the neural tube and somiteosteoprotegerin-deficient mice develop early onset osteoporosis and arterial calcificationSite-directed point mutations in embryonic stem cells: a gene-targeting tag-and-exchange strategyBmp4 is required for the generation of primordial germ cells in the mouse embryoThe 'ins' and 'outs' of podosomes and invadopodia: characteristics, formation and functionMMP-9/gelatinase B is a key regulator of growth plate angiogenesis and apoptosis of hypertrophic chondrocytesHigh-fidelity gene targeting in embryonic stem cells by using sequence replacement vectorsAssociation between B-lymphocyte membrane immunoglobulin and multiple members of the Src family of protein tyrosine kinasesTargeted disruption of a human interferon-inducible gene detected by secretion of human growth hormoneA targeted mutation in the murine gene encoding the high density lipoprotein (HDL) receptor scavenger receptor class B type I reveals its key role in HDL metabolismThe novel adaptor protein Tks4 (SH3PXD2B) is required for functional podosome formationFibronectin-stimulated signaling from a focal adhesion kinase-c-Src complex: involvement of the Grb2, p130cas, and Nck adaptor proteins
P2860
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P2860
Targeted disruption of the c-src proto-oncogene leads to osteopetrosis in mice
description
1991 nî lūn-bûn
@nan
1991 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
1991 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
1991年の論文
@ja
1991年論文
@yue
1991年論文
@zh-hant
1991年論文
@zh-hk
1991年論文
@zh-mo
1991年論文
@zh-tw
1991年论文
@wuu
name
Targeted disruption of the c-src proto-oncogene leads to osteopetrosis in mice
@ast
Targeted disruption of the c-src proto-oncogene leads to osteopetrosis in mice
@en
type
label
Targeted disruption of the c-src proto-oncogene leads to osteopetrosis in mice
@ast
Targeted disruption of the c-src proto-oncogene leads to osteopetrosis in mice
@en
prefLabel
Targeted disruption of the c-src proto-oncogene leads to osteopetrosis in mice
@ast
Targeted disruption of the c-src proto-oncogene leads to osteopetrosis in mice
@en
P2093
P3181
P1433
P1476
Targeted disruption of the c-src proto-oncogene leads to osteopetrosis in mice
@en
P2093
P304
P3181
P356
10.1016/0092-8674(91)90499-O
P407
P4510
P577
1991-02-01T00:00:00Z