mCRY1 and mCRY2 are essential components of the negative limb of the circadian clock feedback loop
about
Genomic convergence among ERRĪ±, PROX1, and BMAL1 in the control of metabolic clock outputsMachine learning helps identify CHRONO as a circadian clock componentFrom biological clock to biological rhythms.A direct repeat of E-box-like elements is required for cell-autonomous circadian rhythm of clock genesHuman and Drosophila cryptochromes are light activated by flavin photoreduction in living cellsCLIF, a novel cycle-like factor, regulates the circadian oscillation of plasminogen activator inhibitor-1 gene expressionNucleocytoplasmic shuttling and mCRY-dependent inhibition of ubiquitylation of the mPER2 clock proteinModeling of a human circadian mutation yields insights into clock regulation by PER2Expression of the gene for Dec2, a basic helix-loop-helix transcription factor, is regulated by a molecular clock systemp75 neurotrophin receptor is a clock gene that regulates oscillatory components of circadian and metabolic networksCoupling of human circadian and cell cycles by the timeless protein.Alternative splicing yields novel BMAL2 variants: tissue distribution and functional characterizationThe transcriptional repressor ID2 can interact with the canonical clock components CLOCK and BMAL1 and mediate inhibitory effects on mPer1 expressionPML regulates PER2 nuclear localization and circadian functionSCFbeta-TRCP controls clock-dependent transcription via casein kinase 1-dependent degradation of the mammalian period-1 (Per1) proteinBiochemical analysis of the canonical model for the mammalian circadian clockA molecular mechanism for circadian clock negative feedbackProtein phosphatase 1 (PP1) is a post-translational regulator of the mammalian circadian clockFunctional analysis of the basic helix-loop-helix transcription factor DEC1 in circadian regulation. Interaction with BMAL1Mammalian TIMELESS is involved in period determination and DNA damage-dependent phase advancing of the circadian clockAUF1 contributes to Cryptochrome1 mRNA degradation and rhythmic translationCommon pathways in circadian and cell cycle clocks: light-dependent activation of Fos/AP-1 in zebrafish controls CRY-1a and WEE-1Nuclear entry mechanism of rat PER2 (rPER2): role of rPER2 in nuclear localization of CRY proteinNuclear entry of the circadian regulator mPER1 is controlled by mammalian casein kinase I epsilonNuclear export of mammalian PERIOD proteinsThe circadian regulatory proteins BMAL1 and cryptochromes are substrates of casein kinase IepsilonA noncanonical E-box enhancer drives mouse Period2 circadian oscillations in vivoDual roles of FBXL3 in the mammalian circadian feedback loops are important for period determination and robustness of the clockIdentification of functional clock-controlled elements involved in differential timing of Per1 and Per2 transcriptionInterlocked feedback loops contribute to the robustness of the Neurospora circadian clockDual modification of BMAL1 by SUMO2/3 and ubiquitin promotes circadian activation of the CLOCK/BMAL1 complexOscillating perceptions: the ups and downs of the CLOCK protein in the mouse circadian systemInteraction of circadian clock proteins PER2 and CRY with BMAL1 and CLOCKDifferential effects of PER2 phosphorylation: molecular basis for the human familial advanced sleep phase syndrome (FASPS)Differential regulation of mammalian period genes and circadian rhythmicity by cryptochromes 1 and 2Feedback repression is required for mammalian circadian clock functionFunctional redundancy of cryptochromes and classical photoreceptors for nonvisual ocular photoreception in miceTime- and exercise-dependent gene regulation in human skeletal muscleA role for cryptochromes in sleep regulationTranscriptional oscillation of canonical clock genes in mouse peripheral tissues
P2860
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P2860
mCRY1 and mCRY2 are essential components of the negative limb of the circadian clock feedback loop
description
1999 nĆ® lÅ«n-bĆ»n
@nan
1999 Õ©ÕøÖÕ”ÕÆÕ”Õ¶Õ« Õ
ÕøÖÕ¬Õ«Õ½Õ«Õ¶ Õ°ÖÕ”ÕæÕ”ÖÕ”ÕÆÕøÖÕ”Õ® Õ£Õ«ÕæÕ”ÕÆÕ”Õ¶ ÕµÖ
Õ¤ÕøÖÕ”Õ®
@hyw
1999 Õ©Õ¾Õ”ÕÆÕ”Õ¶Õ« Õ°ÕøÖÕ¬Õ«Õ½Õ«Õ¶ Õ°ÖÕ”ÕæÕ”ÖÕ”ÕÆÕ¾Õ”Õ® Õ£Õ«ÕæÕ”ÕÆÕ”Õ¶ Õ°ÕøÕ¤Õ¾Õ”Õ®
@hy
1999幓ć®č«ę
@ja
1999幓č«ę
@yue
1999幓č«ę
@zh-hant
1999幓č«ę
@zh-hk
1999幓č«ę
@zh-mo
1999幓č«ę
@zh-tw
1999幓č®ŗę
@wuu
name
mCRY1 and mCRY2 are essential ...... circadian clock feedback loop
@ast
mCRY1 and mCRY2 are essential ...... circadian clock feedback loop
@en
type
label
mCRY1 and mCRY2 are essential ...... circadian clock feedback loop
@ast
mCRY1 and mCRY2 are essential ...... circadian clock feedback loop
@en
prefLabel
mCRY1 and mCRY2 are essential ...... circadian clock feedback loop
@ast
mCRY1 and mCRY2 are essential ...... circadian clock feedback loop
@en
P2093
P3181
P1433
P1476
mCRY1 and mCRY2 are essential ...... circadian clock feedback loop
@en
P2093
Hastings MH
Maywood ES
Reppert SM
Shearman LP
P304
P3181
P356
10.1016/S0092-8674(00)81014-4
P407
P577
1999-07-23T00:00:00Z