A mutant Drosophila insulin receptor homolog that extends life-span and impairs neuroendocrine function
about
Statin treatment increases lifespan and improves cardiac health in Drosophila by decreasing specific protein prenylationAntagonizing Methuselah to extend life spanGenetic variation in healthy oldest-oldTranscriptional profiling of MnSOD-mediated lifespan extension in Drosophila reveals a species-general network of aging and metabolic genesDiapause in the pea aphid (Acyrthosiphon pisum) is a slowing but not a cessation of developmentIncreased proteasome activity in human embryonic stem cells is regulated by PSMD11Evidence that the gene encoding insulin degrading enzyme influences human lifespanLife extension in Drosophila by feeding a drug.High-quality life extension by the enzyme peptide methionine sulfoxide reductaseGrowth hormone receptor deficiency is associated with a major reduction in pro-aging signaling, cancer, and diabetes in humansExtreme-longevity mutations orchestrate silencing of multiple signaling pathwaysRegulation of lifespan in Drosophila by modulation of genes in the TOR signaling pathwayRole of the GH/IGF-1 axis in lifespan and healthspan: lessons from animal models.Suppression of aging in mice by the hormone KlothoKlotho and agingSHC-1/p52Shc targets the insulin/IGF-1 and JNK signaling pathways to modulate life span and stress response in C. elegansVitellogenin, juvenile hormone, insulin signaling, and queen honey bee longevityDoxycycline-induced expression of sense and inverted-repeat constructs modulates phosphogluconate mutase (Pgm) gene expression in adult Drosophila melanogasterThe Drosophila forkhead transcription factor FOXO mediates the reduction in cell number associated with reduced insulin signalingA search for doxycycline-dependent mutations that increase Drosophila melanogaster life span identifies the VhaSFD, Sugar baby, filamin, fwd and Cctl genesDissecting Nck/Dock signaling pathways in Drosophila visual system.The temporal requirements for insulin signaling during development in Drosophila.Using Drosophila to discover mechanisms underlying type 2 diabetesHormesis: Decoding Two Sides of the Same CoinLong live FOXO: unraveling the role of FOXO proteins in aging and longevityDietary Restriction and Nutrient Balance in AgingBiochemical Genetic Pathways that Modulate Aging in Multiple SpeciesRegulation of protein homeostasis in neurodegenerative diseases: the role of coding and non-coding genesWIPI-Mediated Autophagy and LongevityCaenorhabditis elegans as a model organism to study APP functionGenetics and epigenetics of aging and longevityFOXO3: A Major Gene for Human Longevity--A Mini-ReviewNutrient control of Drosophila longevityComparative approaches to the study of physiology: Drosophila as a physiological tool.dbl-1/TGF-β and daf-12/NHR Signaling Mediate Cell-Nonautonomous Effects of daf-16/FOXO on Starvation-Induced Developmental ArrestA genetic strategy to measure circulating Drosophila insulin reveals genes regulating insulin production and secretionDoes reduced IGF-1R signaling in Igf1r+/- mice alter aging?Slowed aging during reproductive dormancy is reflected in genome-wide transcriptome changes in Drosophila melanogaster.Brain IGF-1 receptors control mammalian growth and lifespan through a neuroendocrine mechanismBranched-chain amino acid catabolism is a conserved regulator of physiological ageing.
P2860
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P2860
A mutant Drosophila insulin receptor homolog that extends life-span and impairs neuroendocrine function
description
2001 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Science
@fr
artículu científicu espublizáu en 2001
@ast
im April 2001 veröffentlichter wissenschaftlicher Artikel
@de
scientific article (publication date: 6 April 2001)
@en
wetenschappelijk artikel (gepubliceerd op 2001/04/06)
@nl
наукова стаття, опублікована у квітні 2001
@uk
مقالة علمية (نشرت في 6-4-2001)
@ar
name
A mutant Drosophila insulin re ...... mpairs neuroendocrine function
@ast
A mutant Drosophila insulin re ...... mpairs neuroendocrine function
@en
type
label
A mutant Drosophila insulin re ...... mpairs neuroendocrine function
@ast
A mutant Drosophila insulin re ...... mpairs neuroendocrine function
@en
prefLabel
A mutant Drosophila insulin re ...... mpairs neuroendocrine function
@ast
A mutant Drosophila insulin re ...... mpairs neuroendocrine function
@en
P2093
P921
P3181
P356
P1433
P1476
A mutant Drosophila insulin re ...... mpairs neuroendocrine function
@en
P2093
P304
P3181
P356
10.1126/SCIENCE.1057987
P407
P577
2001-04-06T00:00:00Z