arrow encodes an LDL-receptor-related protein essential for Wingless signalling
about
Subcellular localization of frizzled receptors, mediated by their cytoplasmic tails, regulates signaling pathway specificityThe Frizzled family: receptors for multiple signal transduction pathwaysSp1 and KLF15 regulate basal transcription of the human LRP5 geneDisulfide bond assignments of secreted Frizzled-related protein-1 provide insights about Frizzled homology and netrin modulesSecond cysteine-rich domain of Dickkopf-2 activates canonical Wnt signaling pathway via LRP-6 independently of dishevelledIdentification of the Wnt signaling activator leucine-rich repeat in Flightless interaction protein 2 by a genome-wide functional analysisHelicobacter pylori-induced activation of beta-catenin involves low density lipoprotein receptor-related protein 6 and DishevelledThe low density lipoprotein receptor-related protein 6 interacts with glycogen synthase kinase 3 and attenuates activityLDL receptor-related protein LRP6 regulates proliferation and survival through the Wnt cascade in vascular smooth muscle cellsTransmembrane protein 198 promotes LRP6 phosphorylation and Wnt signaling activationA novel set of Wnt-Frizzled fusion proteins identifies receptor components that activate beta -catenin-dependent signalingAn LRP5 receptor with internal deletion in hyperparathyroid tumors with implications for deregulated WNT/beta-catenin signalingSOST is a ligand for LRP5/LRP6 and a Wnt signaling inhibitorRegulation of secreted Frizzled-related protein-1 by heparinThe low density lipoprotein receptor-1, LRP1, interacts with the human frizzled-1 (HFz1) and down-regulates the canonical Wnt signaling pathwayThe human Frizzled 6 (HFz6) acts as a negative regulator of the canonical Wnt. beta-catenin signaling cascadeWnt induces LRP6 signalosomes and promotes dishevelled-dependent LRP6 phosphorylationThe postsynaptic density 95/disc-large/zona occludens protein syntenin directly interacts with frizzled 7 and supports noncanonical Wnt signalingA novel mechanism for Wnt activation of canonical signaling through the LRP6 receptorMutations in LRP5 or FZD4 underlie the common familial exudative vitreoretinopathy locus on chromosome 11q.Sequence requirement and subtype specificity in the high-affinity interaction between human frizzled and dishevelled proteinsWnt-5a inhibits the canonical Wnt pathway by promoting GSK-3-independent beta-catenin degradationThe pseudoreceptor BMP and activin membrane-bound inhibitor positively modulates Wnt/beta-catenin signalingRegulation of Wnt/LRP signaling by distinct domains of Dickkopf proteins.Small molecule modulation of Smoothened activityLow-density lipoprotein receptor-related protein 5 (LRP5) is essential for normal cholesterol metabolism and glucose-induced insulin secretionA mutational analysis of dishevelled in Drosophila defines novel domains in the dishevelled protein as well as novel suppressing alleles of axinA mutation in the LDL receptor-related protein 5 gene results in the autosomal dominant high-bone-mass traitA model for familial exudative vitreoretinopathy caused by LPR5 mutationsWnt/beta-catenin signaling: components, mechanisms, and diseasesShared molecular mechanisms regulate multiple catenin proteins: canonical Wnt signals and components modulate p120-catenin isoform-1 and additional p120 subfamily members.The Wnt-dependent signaling pathways as target in oncology drug discoveryLrp5 controls bone formation by inhibiting serotonin synthesis in the duodenumWnt signaling: the good and the badThe links between axin and carcinogenesisCoactivation of Rac and Rho by Wnt/Frizzled signaling is required for vertebrate gastrulationLow density lipoprotein receptor-related protein is a calreticulin coreceptor that signals focal adhesion disassemblyHMG box transcription factor TCF-4's interaction with CtBP1 controls the expression of the Wnt target Axin2/Conductin in human embryonic kidney cellsInhibition of Hedgehog signaling by direct binding of cyclopamine to SmoothenedElevated levels of beta-catenin and fibronectin in three-dimensional collagen cultures of Dupuytren's disease cells are regulated by tension in vitro
P2860
Q21092832-E88F8C9A-4F6D-4A2F-9CA5-8F29E0A6EB1DQ21092882-E7FD1D96-B6EC-4143-A2F3-7749FDDA2DE6Q21093395-BFDF99C6-30E4-4EFD-9C31-2496ED8F7BC8Q24292002-1C5A934A-EF87-465C-BD84-A6CCEFA89E28Q24292013-49B44ADB-7A23-46A9-BF44-164FF0E8FD99Q24292985-6A93624B-EDE0-44BC-B825-912748893A6EQ24298548-6D21CA65-14BC-48D0-B456-F665C7A697C8Q24299312-0C9FB964-1994-4C77-A124-26E2073EB3D8Q24299937-B2E71B37-33F2-4BE0-AC29-A41347E30705Q24300997-B407215D-865C-4B92-8D8F-D267C0E7F7E2Q24301647-BE281163-003F-408E-8EE7-9C7D4DF9008BQ24301656-A47AA518-381F-49C3-BF8C-59B3BF18F4DFQ24303393-F2EA2431-D1D5-47A0-AC62-87D6243D7E53Q24305548-686FF27E-A507-4B2F-9FB5-4DC50B4E5009Q24305980-027A0B00-BB2A-4F8C-B4AF-342E12B162ABQ24306497-9B1949A0-2932-475C-A9CF-9BCD7F962051Q24310980-06DB9982-A578-4803-A6E8-AC42CA6258F4Q24311477-906CDFFC-09AD-4E91-BE07-8BB426509CFFQ24313393-C8E0F852-8F99-4DC3-846E-65CC51A32F29Q24317292-5B5393F1-3ABE-43AF-83F8-F21D214006DCQ24318774-0AC85C17-92D3-42C4-A741-85A9DA0375B1Q24319714-43312E08-C0AF-43D3-85EB-5047DC5D4102Q24319976-EC341F2B-CA2A-490C-AC8F-406E8BF5811CQ24537749-57D86A4B-B4AA-43D0-B3F0-004B943695DCQ24540343-E092E248-054E-4EDE-8F16-CC119855F110Q24541297-CCB12A65-03A0-40A6-8FC9-A5998AEA2DEBQ24542617-A150F05F-2305-4D3B-8F0F-E1233300FF1DQ24561917-08BBF693-D080-4582-BD47-00B8C89A4CA9Q24611293-5263DACF-028F-474F-A9C8-EC4C503DF0BAQ24630938-4AD239B6-7F07-4EA6-BFDD-DCF2D722CDB3Q24632319-00DC2B05-8925-4622-9971-6C45468ECB58Q24652979-BC42D462-55C7-4E84-A77D-6056541D5D29Q24653502-B8743328-6F3A-4897-94C0-EAD9F5D58532Q24653563-371F6754-0670-48BD-9FE7-4623807D3FF2Q24672469-573AE256-A9C4-4E43-9A43-73CC601F157FQ24672832-7DCED0A3-474A-4618-B363-E9F5453E85FCQ24674992-F3059D63-2742-40B9-A32D-4B6B2D46AAAEQ24678212-70834F21-BF56-4E59-993A-D044742D1798Q24682703-1DD03045-4142-448F-8796-CCEF310133FAQ24793854-A5DCEC54-CF7D-4811-981C-1CE68195FDC1
P2860
arrow encodes an LDL-receptor-related protein essential for Wingless signalling
description
2000 nî lūn-bûn
@nan
2000 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
arrow encodes an LDL-receptor-related protein essential for Wingless signalling
@ast
arrow encodes an LDL-receptor-related protein essential for Wingless signalling
@en
type
label
arrow encodes an LDL-receptor-related protein essential for Wingless signalling
@ast
arrow encodes an LDL-receptor-related protein essential for Wingless signalling
@en
prefLabel
arrow encodes an LDL-receptor-related protein essential for Wingless signalling
@ast
arrow encodes an LDL-receptor-related protein essential for Wingless signalling
@en
P2093
P3181
P356
P1433
P1476
arrow encodes an LDL-receptor-related protein essential for Wingless signalling
@en
P2093
Caldwell K
Schejter E
Schwartz S
Tomlinson A
Vaizel-Ohayon D
P2507
P2888
P304
P3181
P356
10.1038/35035110
P407
P577
2000-09-28T00:00:00Z
P5875
P6179
1019235380