about
Centrosome dysfunction contributes to chromosome instability, chromoanagenesis, and genome reprograming in cancerWhen the genome plays dice: circumvention of the spindle assembly checkpoint and near-random chromosome segregation in multipolar cancer cell mitosesRegulation and function of the interaction between the APC tumour suppressor protein and EB1Involvement of the telomeric protein Pin2/TRF1 in the regulation of the mitotic spindleN-methyl-N'-nitro-N-nitrosoguanidine-induced senescence-like growth arrest in colon cancer cells is associated with loss of adenomatous polyposis coli protein, microtubule organization, and telomeric DNADuplication of ATR inhibits MyoD, induces aneuploidy and eliminates radiation-induced G1 arrestLoss of pRB causes centromere dysfunction and chromosomal instabilityGenome stability is ensured by temporal control of kinetochore-microtubule dynamicsHec1 sequentially recruits Zwint-1 and ZW10 to kinetochores for faithful chromosome segregation and spindle checkpoint controlNuclear pores protect genome integrity by assembling a premitotic and Mad1-dependent anaphase inhibitorHow aneuploidy affects metabolic control and causes cancerCentrosome amplification drives chromosomal instability in breast tumor development.The role of chromosomal instability in tumor initiation.Digital karyotyping identifies thymidylate synthase amplification as a mechanism of resistance to 5-fluorouracil in metastatic colorectal cancer patientsLethality to human cancer cells through massive chromosome loss by inhibition of the mitotic checkpoint.Chromosomal instability and cancer: a complex relationship with therapeutic potentialMolecular origins of cancer: Molecular basis of colorectal cancerUnbalanced replication as a major source of genetic instability in cancer cellsInfectious agents and colorectal cancer: a review of Helicobacter pylori, Streptococcus bovis, JC virus, and human papillomavirusDifferential expression of DHHC9 in microsatellite stable and instable human colorectal cancer subgroupsGenetic instability of cancer cells is proportional to their degree of aneuploidyChromatid cohesion defects may underlie chromosome instability in human colorectal cancersThe adenomatous polyposis coli-binding protein EB1 is associated with cytoplasmic and spindle microtubulesWhen 2+2=5: the origins and fates of aneuploid and tetraploid cellsGenetic reconstruction of individual colorectal tumor historiesUpregulation of tumour associated antigen RCAS1 is implicated in high stages of colorectal cancerDeregulated expression of the human tumor marker CEA and CEA family member CEACAM6 disrupts tissue architecture and blocks colonocyte differentiationThe alternative Ctf18-Dcc1-Ctf8-replication factor C complex required for sister chromatid cohesion loads proliferating cell nuclear antigen onto DNAPredominance of CIN versus MSI in the development of rectal cancer at young age.Genome characteristics of primary carcinomas, local recurrences, carcinomatoses, and liver metastases from colorectal cancer patientsThe molecular basis of lung cancer: molecular abnormalities and therapeutic implicationsMyosins as fundamental components during tumorigenesis: diverse and indispensableRare Cytogenetic Abnormalities and Alteration of microRNAs in Acute Myeloid Leukemia and Response to TherapyGenome management and mismanagement--cell-level opportunities and challenges of whole-genome duplicationMicroRNAs as growth regulators, their function and biomarker status in colorectal cancerPatterns of Chromosomal Aberrations in Solid TumorsConnecting the speckles: Splicing kinases and their role in tumorigenesis and treatment responseThe quiescent cellular state is Arf/p53-dependent and associated with H2AX downregulation and genome stabilityMAPping the Ndc80 loop in cancer: A possible link between Ndc80/Hec1 overproduction and cancer formationMolecular profile of colorectal cancer in Indonesia: is there another pathway?
P2860
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P2860
description
1997 nî lūn-bûn
@nan
1997 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
name
Genetic instability in colorectal cancers
@ast
Genetic instability in colorectal cancers
@en
type
label
Genetic instability in colorectal cancers
@ast
Genetic instability in colorectal cancers
@en
prefLabel
Genetic instability in colorectal cancers
@ast
Genetic instability in colorectal cancers
@en
P3181
P356
P1433
P1476
Genetic instability in colorectal cancers
@en
P2093
Lengauer C
P2888
P3181
P356
10.1038/386623A0
P407
P577
1997-04-10T00:00:00Z
P5875
P6179
1036879517